Caseína quinase
As caseína quinases são uma família de proteínas quinases serina/treonina que regulam vários processos celulares, incluindo a reparação do DNA, os ritmos circadianos e a transdução de sinais. Essas quinases estão envolvidas na fosforilação de numerosas proteínas e estão implicadas em doenças como o câncer, distúrbios neurodegenerativos e síndromes metabólicas. Na CymitQuimica, oferecemos uma seleção de inibidores de caseína quinase para apoiar sua pesquisa em transdução de sinais, regulação do ciclo celular e desenvolvimento terapêutico.
Foram encontrados 138 produtos de "Caseína quinase"
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Epiblastin A
CAS:Epiblastin A inhibits CK1, targets its isoenzymes, and converts EpiSCs to cESCs.Fórmula:C12H10ClN7Pureza:99.45%Cor e Forma:SolidPeso molecular:287.71Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Fórmula:C16H16F3N5Pureza:99.97%Cor e Forma:SolidPeso molecular:335.33PF-670462
CAS:PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.Fórmula:C19H22Cl2FN5Pureza:99.42% - 99.72%Cor e Forma:SolidPeso molecular:410.32XL413
CAS:XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.Fórmula:C14H12ClN3O2Pureza:98.40% - 99.94%Cor e Forma:SolidPeso molecular:289.72SSTC3
CAS:SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.Fórmula:C23H17F3N4O3S2Pureza:98.65% - 99.94%Cor e Forma:SolidPeso molecular:518.53Ref: TM-T13004
1mg99,00€5mg235,00€10mg376,00€25mg615,00€50mg867,00€100mg1.159,00€1mL*10mM (DMSO)238,00€AMG-548
CAS:AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.Fórmula:C29H27N5OPureza:99.91%Cor e Forma:SolidPeso molecular:461.56SR-1277
CAS:SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor, regulating Wee1 activity at the G2/M cell-cycle interface, and antiproliferative.Fórmula:C21H19N9O3SCor e Forma:SolidPeso molecular:477.5CK2/PIM1-IN-1
CAS:CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.Fórmula:C15H9NO4S2Pureza:98%Cor e Forma:SolidPeso molecular:331.374,5,6,7-Tetrabromobenzimidazole
CAS:4,5,6,7-Tetrabromobenzimidazole is a selective and ATP-competitive inhibitor of protein kinase CK2 [1].Fórmula:C7H2Br4N2Cor e Forma:SolidPeso molecular:433.72CK2-IN-9
CAS:CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporterFórmula:C23H29N9OCor e Forma:SolidPeso molecular:447.54Quinalizarin
CAS:Quinalizarin, the most selective CK2 inhibitor, is superior to CX-4945 which is the first-in-class CK2 inhibitor.Fórmula:C14H8O6Pureza:98%Cor e Forma:SolidPeso molecular:272.21Tyrphostin AG 1112
CAS:Tyrphostin AG 1112 is a Bcr-Abl kinase blocker. It can activate the terminal differentiation of K562 cells and the purging of Ph+ cells.Fórmula:C15H10N6Cor e Forma:SolidPeso molecular:274.28PF 4800567 hydrochloride
CAS:casein kinase 1ε inhibitorFórmula:C17H19Cl2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:396.27IQA
CAS:IQA is a casein kinase 2 (CK2) inhibitor.Fórmula:C17H12N2O3Cor e Forma:SolidPeso molecular:292.29(R)-DRF053 dihydrochloride
CAS:cdk/CK1 inhibitor,potent and ATP-competitiveFórmula:C23H29Cl2N7OPureza:98%Cor e Forma:SolidPeso molecular:490.43CK2-IN-6
CAS:CK2-IN-6: Potent CK2 inhibitor for cancer, inflammation, pain, and immune research.Fórmula:C19H16ClN7O2Cor e Forma:SolidPeso molecular:409.83SRPIN-803
CAS:SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.Fórmula:C14H9F3N4O3SPureza:98%Cor e Forma:SolidPeso molecular:370.31Umbralisib sulfate
CAS:Umbralisib sulfate, an oral dual PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), targets CLL T cells for blood cancer research.Fórmula:C31H26F3N5O7SCor e Forma:SolidPeso molecular:669.63Umbralisib tosylate
CAS:Umbralisib tosylate, an oral PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), shows promise for CLL research.Fórmula:C38H32F3N5O6SCor e Forma:SolidPeso molecular:743.75
