Factor Xa
O fator Xa é uma enzima crucial na cascata de coagulação que converte a protrombina em trombina, levando à formação de coágulos sanguíneos. A inibição do fator Xa é uma estratégia terapêutica amplamente utilizada para prevenir e tratar distúrbios tromboembólicos, como trombose venosa profunda, embolia pulmonar e AVC. Na CymitQuimica, oferecemos inibidores do fator Xa para apoiar sua pesquisa em hematologia, saúde cardiovascular e terapia anticoagulante.
Foram encontrados 80 produtos de "Factor Xa"
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Ciraparantag TFA
CAS:<p>Ciraparantag TFA reverses anticoagulants by inhibiting thrombin and factor Xa.</p>Fórmula:C26H50F6N12O6Pureza:98%Cor e Forma:SolidPeso molecular:740.74Ciraparantag
CAS:<p>Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.</p>Fórmula:C22H48N12O2Pureza:98%Cor e Forma:SolidPeso molecular:512.7Darexaban glucuronide
CAS:<p>Darexaban glucuronide is the major component in plasma after oral administration of darexaban to humans. Darexaban (YM150) is a direct inhibitor of factor Xa.</p>Fórmula:C33H38N4O10Cor e Forma:SolidPeso molecular:650.68Tanogitran
CAS:<p>Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.</p>Fórmula:C25H31N7O3Pureza:98%Cor e Forma:SolidPeso molecular:477.56DPC-423
CAS:<p>DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.</p>Fórmula:C25H21ClF4N4O3SPureza:98%Cor e Forma:SolidPeso molecular:568.97Razaxaban hydrochloride
CAS:<p>Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.</p>Fórmula:C24H21ClF4N8O2Pureza:98%Cor e Forma:SolidPeso molecular:564.92Otamixaban
CAS:<p>Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.</p>Fórmula:C25H26N4O4Pureza:98.08%Cor e Forma:SolidPeso molecular:446.5Eribaxaban
CAS:<p>Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.</p>Fórmula:C24H22ClFN4O4Pureza:98.99% - 99.13%Cor e Forma:SolidPeso molecular:484.91Fidexaban
CAS:<p>Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays</p>Fórmula:C25H24F2N6O5Pureza:98.64% - 99.43%Cor e Forma:SolidPeso molecular:526.49LY 517717
CAS:<p>LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).</p>Fórmula:C27H33N5O2Pureza:99.77% - 99.88%Cor e Forma:SolidPeso molecular:459.58Edoxaban
CAS:<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Fórmula:C24H30ClN7O4SPureza:97.67% - 99.71%Cor e Forma:SolidPeso molecular:548.06Zifaxaban
CAS:<p>Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.</p>Fórmula:C20H16ClN3O4SPureza:97.46% - 99.82%Cor e Forma:SolidPeso molecular:429.88BMS-262084
CAS:<p>BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.</p>Fórmula:C18H31N7O5Cor e Forma:SolidPeso molecular:425.48FXIa-IN-1
CAS:<p>FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.</p>Fórmula:C20H19F3N4O5Pureza:98%Cor e Forma:SolidPeso molecular:452.38Frunexian
CAS:<p>Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.</p>Fórmula:C19H26N4O4Pureza:98%Cor e Forma:SolidPeso molecular:374.43AS1468240
CAS:<p>AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.</p>Fórmula:C25H25Cl2N5O3Cor e Forma:SolidPeso molecular:514.4BI-11634
CAS:<p>BI-11634 is a factor Xa inhibitor.</p>Fórmula:C22H23ClN4NaO4Pureza:98%Cor e Forma:SolidPeso molecular:465.89BMS-962212
CAS:<p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>Fórmula:C32H28ClFN8O5Pureza:98%Cor e Forma:SolidPeso molecular:659.07FXIa-IN-7
CAS:<p>FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.</p>Fórmula:C28H28N2O4Pureza:98.55%Cor e Forma:SolidPeso molecular:456.53BMS-654457
CAS:<p>BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).</p>Fórmula:C36H37N5O4Pureza:98%Cor e Forma:SolidPeso molecular:603.71FXa-IN-1
CAS:<p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>Fórmula:C24H18F5N5OCor e Forma:SolidPeso molecular:487.42Dechloro Rivaroxaban
CAS:<p>Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.</p>Fórmula:C19H19N3O5SPureza:98.63%Cor e Forma:SolidPeso molecular:401.44DX-9065A HCl hydrate
CAS:<p>DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.</p>Fórmula:C26H39ClN4O8Pureza:98%Cor e Forma:SolidPeso molecular:571.06BAY 3389934
CAS:<p>BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.</p>Fórmula:C26H30ClN5O7S2Cor e Forma:SolidPeso molecular:624.129RWJ-445167
CAS:<p>RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.</p>Fórmula:C18H24N6O5SPureza:98%Cor e Forma:SolidPeso molecular:436.49FXIa-6f
CAS:<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Fórmula:C31H29ClF2N4O4Cor e Forma:SolidPeso molecular:595.04FXIa-IN-6
CAS:<p>FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.</p>Fórmula:C31H29ClF2N4O4Cor e Forma:SolidPeso molecular:595.04FXIa-IN-9
CAS:<p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>Fórmula:C23H18Cl2F3N9O2Cor e Forma:SolidPeso molecular:580.35FXIa-IN-8
<p>FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.</p>Cor e Forma:Solid5-Chlorothiophene-2-carboxylic acid
CAS:<p>5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.</p>Fórmula:C5H3ClO2SCor e Forma:SolidPeso molecular:162.59
