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Anidrase carbónica

Anidrase carbónica

A anidrase carbônica é uma enzima que catalisa a conversão reversível de dióxido de carbono e água em bicarbonato e prótons. Esta enzima desempenha um papel crucial na manutenção do equilíbrio ácido-base, respiração e transporte de dióxido de carbono no sangue. Inibidores da anidrase carbônica são usados no tratamento de glaucoma, epilepsia e mal da altitude, bem como em pesquisas sobre homeostase ácido-base e troca gasosa. Na CymitQuimica, oferecemos uma gama de inibidores e reagentes de anidrase carbônica de alta qualidade para apoiar sua pesquisa em enzimologia, fisiologia respiratória e desenvolvimento terapêutico.

Foram encontrados 177 produtos de "Anidrase carbónica"

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  • Benzthiazide

    CAS:
    <p>Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.</p>
    Fórmula:C15H14ClN3O4S3
    Pureza:99.34% - 99.79%
    Cor e Forma:Crystals From Acetone Solid
    Peso molecular:431.94
  • Brinzolamide

    CAS:
    <p>Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.</p>
    Fórmula:C12H21N3O5S3
    Pureza:99.84% - >99.99%
    Cor e Forma:Crystalline Solid
    Peso molecular:383.51
  • Topiramate

    CAS:
    <p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>
    Fórmula:C12H21NO8S
    Pureza:99.79% - 99.92%
    Cor e Forma:White To Off-White Crystalline Powder
    Peso molecular:339.36
  • Actarit

    CAS:
    <p>Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.</p>
    Fórmula:C10H11NO3
    Pureza:99.64% - 99.74%
    Cor e Forma:White Or Off-White Crystal Or Crystalline Solid
    Peso molecular:193.2
  • Methazolamide

    CAS:
    <p>Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.</p>
    Fórmula:C5H8N4O3S2
    Pureza:99.31% - 99.77%
    Cor e Forma:Crystals From Water Solid
    Peso molecular:236.27
  • pNNP

    CAS:
    <p>pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.</p>
    Fórmula:C6H6NO6P
    Pureza:99.73%
    Cor e Forma:Solid
    Peso molecular:219.09
  • Acipimox

    CAS:
    <p>Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.</p>
    Fórmula:C6H6N2O3
    Pureza:98.98%
    Cor e Forma:Low Yellow Liquid Or Crystalline
    Peso molecular:154.12
  • Zonisamide

    CAS:
    <p>Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.</p>
    Fórmula:C8H8N2O3S
    Pureza:99.05% - 99.9%
    Cor e Forma:Off-White Powder
    Peso molecular:212.23
  • Tioxolone

    CAS:
    <p>Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.</p>
    Fórmula:C7H4O3S
    Pureza:97.79%
    Cor e Forma:Light Yellow To Beige Powder
    Peso molecular:168.17
  • Methocarbamol

    CAS:
    <p>Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.</p>
    Fórmula:C11H15NO5
    Pureza:99.96%
    Cor e Forma:Crystals From Benzene Solid
    Peso molecular:241.24
  • Carbonic anhydrase inhibitor 30


    <p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>
    Fórmula:C23H22FN3O5S
    Cor e Forma:Solid
    Peso molecular:471.12642
  • CAIX Inhibitor S4

    CAS:
    <p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>
    Fórmula:C15H17N3O4S
    Pureza:99.07%
    Cor e Forma:Solid
    Peso molecular:335.38
  • hCA/VEGFR-2-IN-4


    <p>hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/</p>
    Fórmula:C22H23FN6O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:502.52
  • Chlorothiazide

    CAS:
    <p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>
    Fórmula:C7H6ClN3O4S2
    Pureza:98.46% - 98.91%
    Cor e Forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)
    Peso molecular:295.72
  • 2-Methoxy-4-propylphenol

    CAS:
    <p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>
    Fórmula:C10H14O2
    Cor e Forma:Solid
    Peso molecular:166.22
  • CAIX/CAXII-IN-4


    <p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>
    Fórmula:C23H21N5O3S
    Cor e Forma:Solid
    Peso molecular:447.51
  • hCA/VEGFR-2-IN-2


    <p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>
    Fórmula:C23H26N6O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:498.55
  • Pyrocatechol

    CAS:
    <p>Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.</p>
    Fórmula:C6H6O2
    Cor e Forma:Solid
    Peso molecular:110.11
  • hCAIX-IN-19


    <p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>
    Cor e Forma:Odour Solid
  • DOTA-XYIMSR-01

    CAS:
    <p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>
    Fórmula:C61H88N16O22S2
    Cor e Forma:Solid
    Peso molecular:1461.57