Anidrase carbónica
A anidrase carbônica é uma enzima que catalisa a conversão reversível de dióxido de carbono e água em bicarbonato e prótons. Esta enzima desempenha um papel crucial na manutenção do equilíbrio ácido-base, respiração e transporte de dióxido de carbono no sangue. Inibidores da anidrase carbônica são usados no tratamento de glaucoma, epilepsia e mal da altitude, bem como em pesquisas sobre homeostase ácido-base e troca gasosa. Na CymitQuimica, oferecemos uma gama de inibidores e reagentes de anidrase carbônica de alta qualidade para apoiar sua pesquisa em enzimologia, fisiologia respiratória e desenvolvimento terapêutico.
Foram encontrados 197 produtos de "Anidrase carbónica"
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EMAC10101d
CAS:compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with anFórmula:C17H15Cl2N3O2S2Pureza:99.96%Cor e Forma:SolidPeso molecular:428.36Dimethylfraxetin
CAS:Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki：0.0097 μM)Fórmula:C12H12O5Pureza:99.96% - ≥95%Cor e Forma:SolidPeso molecular:236.22Trichlormethiazide sodium
CAS:Trichlormethiazide sodium: oral thiazide diuretic, antihypertensive, boosts urine, Na/K excretion, may enhance renal clearance.Fórmula:C8H8Cl3N3NaO4S2Cor e Forma:SolidPeso molecular:403.63Clofenamide
CAS:Clofenamide is a low-ceiling sulfonamide diuretic.Fórmula:C6H7ClN2O4S2Cor e Forma:SolidPeso molecular:270.71hCAII-IN-2
CAS:hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.Fórmula:C25H18ClN5O4SCor e Forma:SolidPeso molecular:519.96hCAIX/XII-IN-3
CAS:Compound 6q inhibits hCAIX/CAXII; K i : hCAI >10000 nM, hCAII >10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.Fórmula:C20H13F3N2O4Cor e Forma:SolidPeso molecular:402.32hCAIX-IN-8
CAS:hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.Fórmula:C19H16N4O6Cor e Forma:SolidPeso molecular:396.35hCAXII-IN-2
CAS:hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.Fórmula:C21H18ClN3O4Cor e Forma:SolidPeso molecular:411.84CDK2-IN-11
CAS:CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.Fórmula:C18H14ClN7O2SCor e Forma:SolidPeso molecular:427.87hCA I-IN-2
CAS:hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).Fórmula:C26H20BrN5O3SCor e Forma:SolidPeso molecular:562.44FC11409B
CAS:FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.Fórmula:C29H23BF4N2O3SCor e Forma:SolidPeso molecular:566.38hCA I-IN-1
CAS:hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).Fórmula:C27H23N5O4SCor e Forma:SolidPeso molecular:513.57hCAXII-IN-3
CAS:hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).Fórmula:C26H20BrN5O3SCor e Forma:SolidPeso molecular:562.44L-693612
CAS:L-693612 is an inhibitor of carbonic anhydrase.Fórmula:C14H24N2O5S3Pureza:98%Cor e Forma:SolidPeso molecular:396.55hCAI/II-IN-4
CAS:hCAI/II-IN-4 inhibits hCA I & II (Ki: 16.95 & 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.Fórmula:C15H15N3O5S2Cor e Forma:SolidPeso molecular:381.43GV2-20
CAS:GV2-20 is an effective carbonic anhydrase 2 inhibitors.Fórmula:C15H13N3O6Pureza:98%Cor e Forma:SolidPeso molecular:331.28Carbonic anhydrase inhibitor 14
CAS:CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.Fórmula:C18H17N7O2SCor e Forma:SolidPeso molecular:395.44hCAXII-IN-5
CAS:hCAXII-IN-5, or compound 6o, is a potent, selective hCAXII inhibitor with Ki values: hCAI & II >10000, hCAIX 286.1, hCAXII 1.0 nM.Fórmula:C23H22N2O4Cor e Forma:SolidPeso molecular:390.43Methazolamide-d6
CAS:Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.Fórmula:C5H2D6N4O3S2Cor e Forma:SolidPeso molecular:242.31L 645151
CAS:L 645151 is an inhibitor of lipophilic CA.Fórmula:C12H14N2O4S2Cor e Forma:SolidPeso molecular:314.38
