Anidrase carbónica
A anidrase carbônica é uma enzima que catalisa a conversão reversível de dióxido de carbono e água em bicarbonato e prótons. Esta enzima desempenha um papel crucial na manutenção do equilíbrio ácido-base, respiração e transporte de dióxido de carbono no sangue. Inibidores da anidrase carbônica são usados no tratamento de glaucoma, epilepsia e mal da altitude, bem como em pesquisas sobre homeostase ácido-base e troca gasosa. Na CymitQuimica, oferecemos uma gama de inibidores e reagentes de anidrase carbônica de alta qualidade para apoiar sua pesquisa em enzimologia, fisiologia respiratória e desenvolvimento terapêutico.
Foram encontrados 197 produtos de "Anidrase carbónica"
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Disulfamide
CAS:Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.Fórmula:C7H9ClN2O4S2Pureza:98.65%Cor e Forma:SolidPeso molecular:284.74AHR-15010
CAS:AHR-15010 is a novel anti-arthritic agent.Fórmula:C10H16N2O8S2Pureza:98%Cor e Forma:SolidPeso molecular:356.37L-693612 HCl
CAS:L-693612 HCl is an inhibitor of carbonic anhydrase.Fórmula:C14H25ClN2O5S3Pureza:98%Cor e Forma:SolidPeso molecular:433.01hCAIX-IN-5
CAS:hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.Fórmula:C18H12FNO3Pureza:99.25%Cor e Forma:SolidPeso molecular:309.29hCAIX-IN-7
CAS:hCAIX-IN-7 (6c) selectively inhibits tumor-related isoform hCAIX (KI: 410.6 nM) and weakly affects hCAI/II (KI: >10000 nM).Fórmula:C18H12FNO3Cor e Forma:SolidPeso molecular:309.29Carbonic anhydrase inhibitor 13
CAS:Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).Fórmula:C17H15N5O3S2Cor e Forma:SolidPeso molecular:401.46WES-1
CAS:WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,Fórmula:C20H20N4O3SPureza:98%Cor e Forma:SolidPeso molecular:396.46hCAIX-IN-3
CAS:hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.Fórmula:C21H21BrN6O4SCor e Forma:SolidPeso molecular:533.4hCAIX-IN-14
CAS:hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM .Fórmula:C11H17ClN6O2SCor e Forma:SolidPeso molecular:332.81Carbonic anhydrase inhibitor 7
CAS:Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.Fórmula:C23H17N3O5SCor e Forma:SolidPeso molecular:447.46hCAXII-IN-1
CAS:hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.Fórmula:C20H17NO5Cor e Forma:SolidPeso molecular:351.35Quinethazone
CAS:Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.Fórmula:C10H12ClN3O3SCor e Forma:Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)Peso molecular:289.74hCAIX-IN-10
CAS:"hCAIX-IN-10 (6i) selectively inhibits carbonic anhydrase IX/XII (Ki: 61.5/586.8 nM), markers in tumor cells, affecting acid-base balance."Fórmula:C28H21N3O3SCor e Forma:SolidPeso molecular:479.55hCAIX-IN-6
CAS:6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.Fórmula:C18H12N2O4SCor e Forma:SolidPeso molecular:352.36DTP348
CAS:DTP348: Oral carbonic anhydrase IX inhibitor & hypoxic cell radiosensitizer with sulfamide & 5-nitroimidazole components.Fórmula:C6H11N5O4SCor e Forma:SolidPeso molecular:249.25Carbonic anhydrase inhibitor 11
CAS:Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.Fórmula:C19H15F3N4O3S2Cor e Forma:SolidPeso molecular:468.47hCAIX/XII-IN-4
CAS:hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and >10000 nM (CAI/CAII).Fórmula:C20H16N2O5Cor e Forma:SolidPeso molecular:364.35HCAIX-IN-2
CAS:HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).Fórmula:C19H16N8O4SCor e Forma:SolidPeso molecular:452.45hCAXII-IN-4
CAS:hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.Fórmula:C22H27N5O6SCor e Forma:SolidPeso molecular:489.54hCAIX-IN-11
CAS:hCAIX-IN-11 inhibits carbonic anhydrases IX & XII with Ki of 32.7 nM & 623.5 nM, respectively.Fórmula:C21H15ClN4O3Cor e Forma:SolidPeso molecular:406.82
