Anidrase carbónica
A anidrase carbônica é uma enzima que catalisa a conversão reversível de dióxido de carbono e água em bicarbonato e prótons. Esta enzima desempenha um papel crucial na manutenção do equilíbrio ácido-base, respiração e transporte de dióxido de carbono no sangue. Inibidores da anidrase carbônica são usados no tratamento de glaucoma, epilepsia e mal da altitude, bem como em pesquisas sobre homeostase ácido-base e troca gasosa. Na CymitQuimica, oferecemos uma gama de inibidores e reagentes de anidrase carbônica de alta qualidade para apoiar sua pesquisa em enzimologia, fisiologia respiratória e desenvolvimento terapêutico.
Foram encontrados 198 produtos para "Anidrase carbónica".
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hCAIX/XII-IN-2
CAS:Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).Fórmula:C19H14N2O4Cor e Forma:SolidPeso molecular:334.33hCAIX-IN-5
CAS:hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.Fórmula:C18H12FNO3Pureza:99.25%Cor e Forma:Red SolidPeso molecular:309.29Ref: TM-T60745
1mg152,00€1mL*10mM (DMSO)245,00€5mg356,00€10mg512,00€25mg802,00€50mg1.108,00€100mg1.468,00€hCAIX-IN-6
CAS:6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.Fórmula:C18H12N2O4SCor e Forma:SolidPeso molecular:352.36DTP348
CAS:DTP348: Oral carbonic anhydrase IX inhibitor & hypoxic cell radiosensitizer with sulfamide & 5-nitroimidazole components.Fórmula:C6H11N5O4SCor e Forma:SolidPeso molecular:249.25Carbonic anhydrase inhibitor 11
CAS:Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.Fórmula:C19H15F3N4O3S2Cor e Forma:SolidPeso molecular:468.47hCAIX/XII-IN-4
CAS:hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and >10000 nM (CAI/CAII).Fórmula:C20H16N2O5Cor e Forma:SolidPeso molecular:364.35hCAIX-IN-10
CAS:hCAIX-IN-10 is a selective hCA IX inhibitor; Ki=7.1 nM; pH regulator; inhibits tumor metastasis; cancer research.Fórmula:C28H21N3O3SPureza:99.33%Cor e Forma:White SolidPeso molecular:479.55Carbonic anhydrase inhibitor 6
CAS:Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.Fórmula:C26H25N3O5SPureza:99.38%Cor e Forma:Yellow SolidPeso molecular:491.56Ref: TM-T63305
1mg164,00€2mg234,00€5mg389,00€10mg532,00€25mg820,00€50mg1.063,00€100mg1.350,00€200mg1.783,00€Sultiame
CAS:Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.Fórmula:C10H14N2O4S2Pureza:99.91%Cor e Forma:SolidPeso molecular:290.36hCAII-IN-9
CAS:hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.Fórmula:C15H16ClN3O5S2Pureza:99.87%Cor e Forma:SolidPeso molecular:417.89hCAI/II-IN-6
CAS:hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).Fórmula:C19H24N4O3SPureza:98.49%Cor e Forma:SolidPeso molecular:388.48COX-2-IN-30
CAS:COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =Fórmula:C17H16N6O3SPureza:98%Cor e Forma:SolidPeso molecular:384.41CAXII-IN-1
CAS:CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.Fórmula:C13H7Cl2NO3SCor e Forma:SolidPeso molecular:328.17TSPO/Carbonic Anhydrase Modulator 1
CAS:TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.Fórmula:C35H51N3O3Cor e Forma:SolidPeso molecular:561.798N-Desethyl Brinzolamide oxalate
CAS:N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].Fórmula:C12H19N3O9S3Cor e Forma:SolidPeso molecular:445.49Sezolamide hydrochloride
CAS:Sezolamide hydrochloride is a potent topical carbonic anhydrase inhibitor.Fórmula:C11H19ClN2O4S3Cor e Forma:SolidPeso molecular:374.93Sezolamide
CAS:Sezolamide is a carbonic anhydrase inhibitor.Fórmula:C11H18N2O4S3Cor e Forma:SolidPeso molecular:338.47Carbonic anhydrase inhibitor 12
CAS:CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.Fórmula:C27H22BrN5O5S2Pureza:98%Cor e Forma:SolidPeso molecular:640.53hCAIX-IN-16
CAS:hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.Fórmula:C20H20N8O2SPureza:98%Cor e Forma:SolidPeso molecular:436.49ALP/Carbonic anhydrase-IN-1
CAS:Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkalineFórmula:C15H16N2Pureza:98%Cor e Forma:SolidPeso molecular:224.3
