ROR
Os receptores órfãos relacionados ao ácido retinoico (RORs) são receptores nucleares que regulam vários processos fisiológicos, incluindo ritmo circadiano, resposta imune e metabolismo. Inibidores de RORs são de grande interesse no estudo de doenças autoimunes, distúrbios metabólicos e câncer, pois podem modular a expressão gênica e influenciar as funções celulares. Na CymitQuimica, oferecemos inibidores de RORs para apoiar sua pesquisa em imunologia, endocrinologia e oncologia.
Foram encontrados 51 produtos para "ROR".
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RORγt inverse agonist 14
CAS:RORγt inverse agonist 14 (8e) is a potent, selective, and orally active compound with an EC50 of 2.5 nM, exhibiting anti-inflammatory activity.Fórmula:C26H26F8N2O6S2Pureza:98%Cor e Forma:SolidPeso molecular:678.61RORγt Inverse agonist 6
CAS:RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases.Fórmula:C28H29ClN6O5Pureza:99.52%Cor e Forma:SolidPeso molecular:565.02JTE-151
CAS:JTE-151, a RORγ inhibitor, suppresses the overactive immune response by inhibiting RORγ, which is linked to the activation of Th17 cells. This action positions JTE-151 as a potential candidate for autoimmune disease research [1].Fórmula:C28H37ClN2O4Peso molecular:501.06LDR102
CAS:LDR102 (Compound 19h) is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) with a Ki value of 0.10 μM.Fórmula:C33H27N5O3Pureza:97.42% - 99.52%Cor e Forma:SolidPeso molecular:541.6RORγt inverse agonist 32
CAS:RORγt inverse agonist 32 (compound b14) exhibits oral activity and can be utilized in inflammatory research studies.Fórmula:C24H28F3NO5SCor e Forma:SolidPeso molecular:499.54TAK-828F
CAS:TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.Fórmula:C28H32FN3O5Pureza:98%Cor e Forma:SolidPeso molecular:509.57RORγ-IN-2
CAS:RORγ-IN-2 (Compound 22) is an inhibitor of RORγ, with a Ki value of 16.6 nM for hRORγ. It is useful for research in IL-17-dependent autoimmune diseases.Fórmula:C28H32F3N5O4S2Cor e Forma:SolidPeso molecular:623.71RORγt inhibitor 4
CAS:RORγt inhibitor 4 (Compound 9a) is an orally active RORγt inhibitor capable of penetrating the central nervous system. It has been shown to improve experimental autoimmune encephalomyelitis.Fórmula:C22H16Cl2F3NO4SCor e Forma:SolidPeso molecular:518.333RORγt inverse agonist 34
CAS:RORγt inverse agonist 34 (compound 5a) is an inverse agonist for RORγt, exhibiting an IC50 of 0.094 μM for the inhibition of RORγt-LBD. This compound is utilized in psoriasis research.Fórmula:C31H37N3O3SCor e Forma:SolidPeso molecular:531.709Hexyl 4-hydroxybenzoate
CAS:Hexyl 4-hydroxybenzoate (Hexylparaben) is an agonist of the retinoic acid-related orphan receptor RORγ(t) with an EC50 of 144 nM. It is applicable in the study of autoimmune diseases.Fórmula:C13H18O3Peso molecular:222.2802Vimirogant
CAS:Vimirogant is a RORγ inhibitor (Ki: <100 nM).Fórmula:C27H35F3N4O3SPureza:98%Cor e Forma:SolidPeso molecular:552.65
