PPAR
Os receptores ativados por proliferadores de peroxissomas (PPARs) são um grupo de proteínas receptoras nucleares que funcionam como fatores de transcrição, regulando a expressão de genes envolvidos no metabolismo, particularmente no armazenamento de ácidos graxos e no metabolismo da glicose. Inibidores de PPAR são ferramentas importantes para o estudo de distúrbios metabólicos como diabetes, obesidade e doenças cardiovasculares. Esses inibidores podem modular o metabolismo lipídico, a sensibilidade à insulina e a inflamação, tornando-os valiosos na pesquisa terapêutica. Na CymitQuimica, oferecemos uma gama de inibidores de PPAR para apoiar sua pesquisa em doenças metabólicas, endocrinologia e desenvolvimento de medicamentos.
Foram encontrados 172 produtos para "PPAR".
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Leriglitazone
CAS:Leriglitazone is a brain-permeable PPARγ agonist (EC50=9 μM) and mitochondrial modulator with neuroprotective and anti-inflammatory properties.Fórmula:C19H20N2O4SPureza:99.67%Cor e Forma:SolidPeso molecular:372.44Ref: TM-T15736
1mg147,00€5mg356,00€1mL*10mM (DMSO)393,00€10mg572,00€25mg1.063,00€50mg1.459,00€100mg1.963,00€Anti-obesity agent 1
Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.Fórmula:C21H22N2O6Cor e Forma:SolidPeso molecular:398.409CUDA
CAS:CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.Fórmula:C19H36N2O3Pureza:97.58%Cor e Forma:SolidPeso molecular:340.5MCC-555
CAS:MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.Fórmula:C21H16FNO3SPureza:99.07% - 99.82%Cor e Forma:SolidPeso molecular:381.42Ref: TM-T21764
5mg66,00€1mL*10mM (DMSO)73,00€10mg105,00€25mg215,00€50mg356,00€100mg530,00€500mg1.153,00€CC618
CAS:CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.Fórmula:C20H15F6N3O3S2Pureza:99.94%Cor e Forma:SolidPeso molecular:523.47Ref: TM-T9767
1mg102,00€5mg235,00€1mL*10mM (DMSO)298,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€Anti-osteoporosis agent-10
Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.Cor e Forma:Odour SolidAZD-9574
CAS:AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs.Fórmula:C21H22F2N6O2Pureza:98.46% - 99.39%Cor e Forma:SolidPeso molecular:428.44Lipid Metabolism Compound Library
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Cor e Forma:Odour SolidSulotroban potassium
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.Fórmula:C16H16KNO5SPureza:98.02%Cor e Forma:SoildPeso molecular:373.46Sulotroban
CAS:sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.Fórmula:C16H17NO5SPureza:98.86% - 99.98%Cor e Forma:SolidPeso molecular:335.378-iso Prostaglandin F1β
CAS:8-iso Prostaglandin F1β,inducet vasoconstrictor effects in (PA), (PV) and (MA) through the activation of TXA2R, tyrosine kinase and Rho kinase.Fórmula:C20H36O5Cor e Forma:SolidPeso molecular:356.5Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
CAS:Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.Fórmula:C24H23NO5SPureza:99.59%Cor e Forma:SolidPeso molecular:437.51Ref: TM-T63898
1mg175,00€5mg404,00€1mL*10mM (DMSO)447,00€10mg593,00€25mg888,00€50mg1.251,00€100mg1.693,00€GQ-16
CAS:GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.Fórmula:C19H16BrNO3SPureza:99.84%Cor e Forma:SolidPeso molecular:418.3Ref: TM-T21955
1mL*10mM (DMSO)34,00€10mg37,00€25mg75,00€50mg110,00€100mg177,00€200mg265,00€500mg425,00€8-iso Prostaglandin F1α
CAS:8-iso Prostaglandin F1α induces vasoconstrictor effects in (PA),(PV) and (MA) through activation of TXA2R, tyrosine kinases and Rho kinases.Fórmula:C20H36O5Cor e Forma:SolidPeso molecular:356.5Balaglitazone
CAS:Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Fórmula:C20H17N3O4SPureza:99.74%Cor e Forma:SolidPeso molecular:395.43CP-868388 free base
CAS:CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.Fórmula:C26H33NO5Pureza:99.84%Cor e Forma:White SolidPeso molecular:439.54PPAR α/PPARA Protein, Human, Recombinant (His)
PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.Cor e Forma:Lyophilized PowderPeso molecular:31.36 kDa (predicted)Ref: TM-TMPY-06830
5µg102,00€10µg169,00€20µg266,00€50µg540,00€100µg945,00€200µg1.648,00€500µg3.520,00€Candesartan-D4
CAS:Candesartan-d4 is the deuterated Candesartan; AT1 receptor blocker and PPAR-γ agonist; antihypertensive; internal standard for PK analysis.Fórmula:C24H20N6O3Pureza:98%Cor e Forma:SolidPeso molecular:444.479PPAR α/PPARA Protein, Mouse, Recombinant (His)
PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.Cor e Forma:White Lyophilized PowderPeso molecular:31.49 kDa (predicted)Ref: TM-TMPY-06837
5µg101,00€10µg166,00€20µg266,00€50µg540,00€100µg954,00€200µg1.665,00€500µg4.078,00€GW6471
CAS:GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.Fórmula:C35H36F3N3O4Pureza:98.23% - 99.55%Cor e Forma:SolidPeso molecular:619.67Ref: TM-T8486
2mg34,00€5mg50,00€10mg84,00€1mL*10mM (DMSO)93,00€25mg167,00€50mg295,00€100mg505,00€200mg760,00€
![Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT63898.webp&w=3840&q=75)
