PPAR
Os receptores ativados por proliferadores de peroxissomas (PPARs) são um grupo de proteínas receptoras nucleares que funcionam como fatores de transcrição, regulando a expressão de genes envolvidos no metabolismo, particularmente no armazenamento de ácidos graxos e no metabolismo da glicose. Inibidores de PPAR são ferramentas importantes para o estudo de distúrbios metabólicos como diabetes, obesidade e doenças cardiovasculares. Esses inibidores podem modular o metabolismo lipídico, a sensibilidade à insulina e a inflamação, tornando-os valiosos na pesquisa terapêutica. Na CymitQuimica, oferecemos uma gama de inibidores de PPAR para apoiar sua pesquisa em doenças metabólicas, endocrinologia e desenvolvimento de medicamentos.
Foram encontrados 170 produtos de "PPAR"
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K-111
CAS:K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.Fórmula:C18H25Cl3O2Pureza:99.64% - 99.88%Cor e Forma:SolidPeso molecular:379.75BAY-4931
CAS:BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.Fórmula:C22H16ClN3O4Pureza:99.73%Cor e Forma:SoildPeso molecular:421.83Ref: TM-T67933
1mg38,00€5mg84,00€10mg119,00€25mg260,00€50mg409,00€100mg605,00€500mg1.288,00€1mL*10mM (DMSO)93,00€Linotroban
CAS:Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.Fórmula:C14H15NO5S2Pureza:97.95% - >99.99%Cor e Forma:SolidPeso molecular:341.4Imiglitazar
CAS:Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.Fórmula:C28H26N2O5Pureza:97.33%Cor e Forma:SolidPeso molecular:470.52Darglitazone
CAS:Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.Fórmula:C23H20N2O4SPureza:99.76%Cor e Forma:SolidPeso molecular:420.48LCB-2853
CAS:LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.Fórmula:C21H24ClNO4SPureza:97.15%Cor e Forma:SolidPeso molecular:421.94KD-3010
CAS:KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.Fórmula:C30H33F3N2O8S2Pureza:99.61%Cor e Forma:SolidPeso molecular:670.72PPARγ agonist 8
CAS:PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferatorFórmula:C19H12F4O2SPureza:98%Cor e Forma:SolidPeso molecular:380.36U-46619
CAS:U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (Fórmula:C21H34O4Pureza:98%Cor e Forma:SolidPeso molecular:350.49PPARδ agonist 9
CAS:PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atheroscleroticFórmula:C26H28ClF3N4O3SPureza:98%Cor e Forma:SolidPeso molecular:569.04PPAR agonist 1
CAS:PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.Fórmula:C20H25NO6SPureza:98%Cor e Forma:SolidPeso molecular:407.48CRX000227
CAS:CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].Fórmula:C25H24N4O2SPureza:98%Cor e Forma:SolidPeso molecular:444.55Edaglitazone
CAS:Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.Fórmula:C24H20N2O4S2Pureza:98%Cor e Forma:SolidPeso molecular:464.56Inolitazone
CAS:Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.Fórmula:C27H26N4O4SPureza:99.41% - 99.53%Cor e Forma:SolidPeso molecular:502.58Ref: TM-T15581
1mg70,00€5mg149,00€10mg230,00€25mg374,00€50mg532,00€100mg713,00€500mgA consultar1mL*10mM (DMSO)178,00€Ragaglitazar
CAS:Ragaglitazar(NNC-61-0029) is a potent dual activator of PPARγ and PPARα.Cost-effective and quality-assured.Fórmula:C25H25NO5Pureza:97.46% - 98.56%Cor e Forma:SolidPeso molecular:419.47PPARγ phosphorylation inhibitor 1
CAS:PPARγ phosphorylation inhibitor 1, PPARγ agonist (IC50=24 nM), inhibits CDK5-mediated Ser273 phosphorylation, antidiabetic activity.Fórmula:C22H14Cl2N2O4Pureza:99.86%Cor e Forma:SolidPeso molecular:441.26Ref: TM-T62554
1mgA consultar5mgA consultar10mg505,00€25mg982,00€50mg1.603,00€1mL*10mM (DMSO)A consultarSR 11023
CAS:SR 11023, an orally active PPAR γ antagonist, exhibits an IC 50 value of 109 nM and is significant in diabetes research [1].Fórmula:C33H36N2O3Cor e Forma:SolidPeso molecular:508.65Anti-NASH agent 2
CAS:Anti-NASH agent 2 (compound 21) is an inhibitor of neolipogenesis activity and α-SMA gene expression. It improves hepatic steatosis, edema, inflammatory infiltration, and liver fibrosis in NASH mouse models.
Fórmula:C32H51N3O2Cor e Forma:SolidPeso molecular:509.766PPARγ agonist 17
CAS:PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.Fórmula:C48H63NO7Cor e Forma:SolidPeso molecular:766.016PPARγ modulator-2
CAS:PPARγmodulator-2 (Compound (R)-2n) is a reversible modulator of PPARγ, inhibiting the PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. It helps lower blood glucose levels, improves glucose tolerance and insulin sensitivity, and demonstrates antidiabetic activity in db/db mouse models.Fórmula:C26H21NO7S3SeCor e Forma:SolidPeso molecular:634.6
