Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 302 produtos de "Desidrogenase"
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Succinyl phosphonate trisodium salt
CAS:Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)Fórmula:C4H4Na3O6PPureza:99.8% - ≥95%Cor e Forma:SolidPeso molecular:248.01Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Cor e Forma:SolidPeso molecular:355.36Mutant IDH1-IN-1
CAS:Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.Fórmula:C30H31FN4O2Pureza:99.49% - >99.99%Cor e Forma:SolidPeso molecular:498.59Ref: TM-T2043
2mg44,00€5mg67,00€10mg94,00€25mg173,00€50mg249,00€100mg363,00€200mg490,00€1mL*10mM (DMSO)71,00€(E/Z)-Teriflunomide
CAS:(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.Fórmula:C12H9F3N2O2Pureza:99.49% - 99.76%Cor e Forma:White SolidPeso molecular:270.21WIN 18446
CAS:inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)Fórmula:C12H20Cl4N2O2Pureza:99.69%Cor e Forma:SolidPeso molecular:366.11AGI-6780
CAS:AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.Fórmula:C21H18F3N3O3S2Pureza:98.19% - 99.7%Cor e Forma:SolidPeso molecular:481.51Ref: TM-T1809
1mg34,00€2mg49,00€5mg74,00€10mg113,00€25mg208,00€50mg371,00€100mg557,00€500mg1.198,00€1mL*10mM (DMSO)80,00€Brequinar sodium
CAS:Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.Fórmula:C23H14F2NNaO2Pureza:98.16%Cor e Forma:SolidPeso molecular:397.36Ref: TM-T8332
2mg37,00€5mg63,00€10mg92,00€25mg168,00€50mg212,00€100mg298,00€200mg420,00€1mL*10mM (DMSO)73,00€Fomepizole
CAS:Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.Fórmula:C4H6N2Pureza:98.1% - 99.94%Cor e Forma:Yellow <13°C Solid >13°C LiquidPeso molecular:82.1Imidazole-5-propionic acid
CAS:Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.Fórmula:C6H8N2O2Pureza:99.62%Cor e Forma:SolidPeso molecular:140.14R162
CAS:R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.Fórmula:C17H12O3Pureza:96.21% - 98.15%Cor e Forma:SolidPeso molecular:264.28Nifurtimox
CAS:Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.Fórmula:C10H13N3O5SPureza:99.87% - 99.89%Cor e Forma:SolidPeso molecular:287.29DS-1001b
CAS:DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)Fórmula:C29H29Cl3FN3O4Pureza:99.81%Cor e Forma:SolidPeso molecular:608.92Ref: TM-T7741
1mg34,00€5mg74,00€10mg113,00€25mg177,00€50mg268,00€100mg416,00€200mg602,00€1mL*10mM (DMSO)92,00€BAY-1436032
CAS:BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).Fórmula:C26H30F3N3O3Pureza:99.65% - 99.71%Cor e Forma:SolidPeso molecular:489.53PfDHODH-IN-2
CAS:PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.Fórmula:C13H12ClNO3SPureza:98.9%Cor e Forma:SolidPeso molecular:297.76Ref: TM-T8767
1mg46,00€5mg92,00€10mg138,00€25mg245,00€50mg363,00€100mg515,00€200mg702,00€1mL*10mM (DMSO)100,00€NCT-503
CAS:NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.Fórmula:C20H23F3N4SPureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:408.48Ref: TM-T4213
2mg39,00€5mg59,00€10mg95,00€25mg177,00€50mg321,00€100mg477,00€200mg667,00€1mL*10mM (DMSO)65,00€VER-246608
CAS:VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.Fórmula:C28H23ClF2N4O4Pureza:98.5%Cor e Forma:SolidPeso molecular:552.96Ref: TM-T17224
1mg50,00€2mg71,00€5mg105,00€10mg166,00€25mg313,00€50mg475,00€100mg692,00€1mL*10mM (DMSO)130,00€BVT-14225
CAS:BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).Fórmula:C16H20ClN3O3S2Pureza:97.78%Cor e Forma:SolidPeso molecular:401.93Ref: TM-T3542
1mg44,00€2mg56,00€5mg90,00€10mg135,00€25mg240,00€50mg389,00€100mg577,00€1mL*10mM (DMSO)100,00€AG-120 (racemic)
CAS:AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.Fórmula:C28H22ClF3N6O3Pureza:99.56%Cor e Forma:SolidPeso molecular:582.96Enasidenib
CAS:Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potentialFórmula:C19H17F6N7OPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:473.38Ref: TM-T2346
5mg44,00€10mg66,00€25mg87,00€50mg105,00€100mg137,00€200mg197,00€500mg333,00€1mL*10mM (DMSO)48,00€BI-187004
CAS:BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.Fórmula:C21H18N4OPureza:98.63%Cor e Forma:SolidPeso molecular:342.39G6PDi-1
CAS:G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.Fórmula:C14H12N4OSPureza:98.69%Cor e Forma:SolidPeso molecular:284.34Tiazofurin
CAS:Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Fórmula:C9H12N2O5SPureza:99.91%Cor e Forma:SolidPeso molecular:260.27BMS-823778 hydrochloride
CAS:BMS-823778 hydrochloride is a potent, selective, and orally active inhibitor of 11β-HSD1 (11β-Hydroxysteroid Dehydrogenase Type 1), demonstrating an IC50 (half
Fórmula:C18H19Cl2N3OCor e Forma:SolidPeso molecular:364.27Proguanil hydrochloride
CAS:Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.Fórmula:C11H17Cl2N5Pureza:98.34% - 98.39%Cor e Forma:SolidPeso molecular:290.19MK-8245
CAS:MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.Fórmula:C17H16BrFN6O4Pureza:97.58% - 99%Cor e Forma:SolidPeso molecular:467.25Ref: TM-T2650
1mg37,00€5mg90,00€10mg144,00€25mg259,00€50mg440,00€100mg615,00€200mg853,00€1mL*10mM (DMSO)92,00€NCT-501 hydrochloride
CAS:NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.Fórmula:C21H33ClN6O3Cor e Forma:SolidPeso molecular:452.98AZD7545
CAS:AZD7545 is a potent PDHK inhibitor.Fórmula:C19H18ClF3N2O5SPureza:99.12% - 99.96%Cor e Forma:SolidPeso molecular:478.87AGI-5198
CAS:AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).Fórmula:C27H31FN4O2Pureza:97.37% - 99.23%Cor e Forma:SolidPeso molecular:462.56Ivosidenib
CAS:Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.Fórmula:C28H22ClF3N6O3Pureza:98.71% - 99.98%Cor e Forma:SolidPeso molecular:582.96NCT-505
CAS:NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 withFórmula:C27H28FN5O3SPureza:99.93%Cor e Forma:SolidPeso molecular:521.61Ref: TM-T12196
1mg109,00€5mg224,00€10mg334,00€25mg532,00€50mg718,00€100mg964,00€200mg1.288,00€1mL*10mM (DMSO)256,00€AKR1C3-IN-4
CAS:AKR1C3-IN-4: potent, selective AKR1C3 inhibitor, IC50 = 0.56 μM, potential for CRPC research.Fórmula:C14H10F3NO2Pureza:98.59%Cor e Forma:SolidPeso molecular:281.23A939572
CAS:A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.Fórmula:C20H22ClN3O3Pureza:99.96% - ≥95%Cor e Forma:SolidPeso molecular:387.86Ref: TM-T4515
1mg34,00€5mg73,00€10mg109,00€25mg213,00€50mg341,00€100mg537,00€200mg777,00€1mL*10mM (DMSO)77,00€Sodium dichloroacetate
CAS:Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.Fórmula:C2HCl2NaO2Pureza:99.32% - 99.87%Cor e Forma:White PowderPeso molecular:150.92LDHA-IN-4
CAS:LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA expressed in E.coli BL21 (DE3) by SPR analysis with an active value of 93 nM.Fórmula:C25H27N3O6SPureza:98.17% - 99.68%Cor e Forma:SolidPeso molecular:497.56AKR1C3-IN-1
CAS:AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).Fórmula:C16H15NO4SPureza:98.02%Cor e Forma:SolidPeso molecular:317.36Galloflavin
CAS:Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.Fórmula:C12H6O8Pureza:96.24% - 97.47%Cor e Forma:SolidPeso molecular:278.17L-Allylglycine
CAS:L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.Fórmula:C5H9NO2Pureza:≥98%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:115.13AG-636
CAS:AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Fórmula:C21H17N3O2Pureza:99.19%Cor e Forma:SolidPeso molecular:343.38Nitrofen
CAS:Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.Fórmula:C12H7Cl2NO3Pureza:99.92%Cor e Forma:Less Crystals Or Black Solid Used As A Pre- Or Post-Emergence HerbicidePeso molecular:284.09CM10
CAS:CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.Fórmula:C20H23N3OPureza:99.84%Cor e Forma:SolidPeso molecular:321.42Carbenoxolone disodium
CAS:Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.Fórmula:C34H48Na2O7Pureza:99.69%Cor e Forma:SolidPeso molecular:614.72Vidofludimus hemicalcium
CAS:Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Fórmula:C20H18FNO4CaCor e Forma:SolidPeso molecular:375.4PHGDH-inactive
CAS:PHGDH inactive is inactive against PHGDH and serves as a negative control for NCT-502 and NCT-503 [1].Fórmula:C17H21N5SPureza:99.83%Cor e Forma:SolidPeso molecular:327.45Ref: TM-T23150
5mg35,00€10mg57,00€25mg111,00€50mg172,00€100mg248,00€200mg348,00€1mL*10mM (DMSO)44,00€PfDHODH-IN-1
CAS:PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Fórmula:C14H11F3N2O2Pureza:99.87%Cor e Forma:SolidPeso molecular:296.24Ref: TM-T12438
1mg52,00€5mg101,00€10mg152,00€25mg295,00€50mg447,00€100mg658,00€200mg888,00€1mL*10mM (DMSO)92,00€Dihydrouracil
CAS:5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.Fórmula:C4H6N2O2Pureza:99.75%Cor e Forma:SolidPeso molecular:114.1NCT-501
CAS:NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.Fórmula:C21H32N6O3Pureza:99.19%Cor e Forma:SolidPeso molecular:416.52DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Fórmula:C20H15NO5Pureza:99.13%Cor e Forma:SolidPeso molecular:349.34Ref: TM-T37655
1mg73,00€5mg160,00€10mg236,00€25mg409,00€50mg595,00€100mg858,00€1mL*10mM (DMSO)170,00€Enasidenib mesylate
CAS:Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.Fórmula:C20H21F6N7O4SPureza:99.85%Cor e Forma:SolidPeso molecular:569.48GSK1940029
CAS:GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.Fórmula:C18H16Cl2N4O2Pureza:99.48% - 99.49%Cor e Forma:SolidPeso molecular:391.25Triflupromazine
CAS:Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.Fórmula:C18H19F3N2SCor e Forma:SolidPeso molecular:352.42
