Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 267 produtos de "Desidrogenase"
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Carbenoxolone disodium
CAS:<p>Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.</p>Fórmula:C34H48Na2O7Pureza:99.69%Cor e Forma:SolidPeso molecular:614.72MK-8245
CAS:<p>MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.</p>Fórmula:C17H16BrFN6O4Pureza:97.58% - 99%Cor e Forma:SolidPeso molecular:467.25NCT-501 hydrochloride
CAS:<p>NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.</p>Fórmula:C21H33ClN6O3Cor e Forma:SolidPeso molecular:452.98Vidofludimus hemicalcium
CAS:Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Fórmula:C20H18FNO4CaCor e Forma:SolidPeso molecular:375.4AG-636
CAS:<p>AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.</p>Fórmula:C21H17N3O2Pureza:99.19%Cor e Forma:SolidPeso molecular:343.38Sodium dichloroacetate
CAS:<p>Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.</p>Fórmula:C2HCl2NaO2Pureza:99.32% - 99.87%Cor e Forma:White PowderPeso molecular:150.92A939572
CAS:<p>A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.</p>Fórmula:C20H22ClN3O3Pureza:99.96% - ≥95%Cor e Forma:SolidPeso molecular:387.86Proguanil hydrochloride
CAS:<p>Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.</p>Fórmula:C11H17Cl2N5Pureza:98.34% - 98.39%Cor e Forma:SolidPeso molecular:290.19Ivosidenib
CAS:<p>Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.</p>Fórmula:C28H22ClF3N6O3Pureza:98.71% - 99.98%Cor e Forma:SolidPeso molecular:582.96Tiazofurin
CAS:<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Fórmula:C9H12N2O5SPureza:99.91%Cor e Forma:SolidPeso molecular:260.27Galloflavin
CAS:<p>Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.</p>Fórmula:C12H6O8Pureza:96.24% - 97.47%Cor e Forma:SolidPeso molecular:278.17NCT-505
CAS:<p>NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with</p>Fórmula:C27H28FN5O3SPureza:99.93%Cor e Forma:SolidPeso molecular:521.61VER-246608
CAS:<p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>Fórmula:C28H23ClF2N4O4Pureza:98.5%Cor e Forma:SolidPeso molecular:552.96Mutant IDH1-IN-1
CAS:<p>Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.</p>Fórmula:C30H31FN4O2Pureza:99.49% - >99.99%Cor e Forma:SolidPeso molecular:498.59NCT-503
CAS:<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C20H23F3N4SPureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:408.48L-Allylglycine
CAS:<p>L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.</p>Fórmula:C5H9NO2Pureza:≥98%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:115.13CM10
CAS:<p>CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.</p>Fórmula:C20H23N3OPureza:99.84%Cor e Forma:SolidPeso molecular:321.42NCT-501
CAS:<p>NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.</p>Fórmula:C21H32N6O3Pureza:99.19%Cor e Forma:SolidPeso molecular:416.52AGI-5198
CAS:<p>AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).</p>Fórmula:C27H31FN4O2Pureza:97.37% - 99.23%Cor e Forma:SolidPeso molecular:462.56Nifurtimox
CAS:<p>Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.</p>Fórmula:C10H13N3O5SPureza:99.87% - 99.89%Cor e Forma:SolidPeso molecular:287.29BAY-1436032
CAS:<p>BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).</p>Fórmula:C26H30F3N3O3Pureza:99.65% - 99.71%Cor e Forma:SolidPeso molecular:489.53WIN 18446
CAS:<p>inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)</p>Fórmula:C12H20Cl4N2O2Pureza:99.69%Cor e Forma:SolidPeso molecular:366.11Brequinar sodium
CAS:<p>Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.</p>Fórmula:C23H14F2NNaO2Pureza:98.16%Cor e Forma:SolidPeso molecular:397.36Fomepizole
CAS:<p>Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.</p>Fórmula:C4H6N2Pureza:98.1% - 99.94%Cor e Forma:Yellow <13°C Solid >13°C LiquidPeso molecular:82.1Imidazole-5-propionic acid
CAS:<p>Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.</p>Fórmula:C6H8N2O2Pureza:99.62%Cor e Forma:SolidPeso molecular:140.14AG-120 (racemic)
CAS:<p>AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.</p>Fórmula:C28H22ClF3N6O3Pureza:99.56%Cor e Forma:SolidPeso molecular:582.96Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Cor e Forma:SolidPeso molecular:355.36BVT-14225
CAS:<p>BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).</p>Fórmula:C16H20ClN3O3S2Pureza:97.78%Cor e Forma:SolidPeso molecular:401.93(R)-GNE-140
CAS:<p>(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.</p>Fórmula:C25H23ClN2O3S2Pureza:98.25% - 98.91%Cor e Forma:SolidPeso molecular:499.04Succinyl phosphonate trisodium salt
CAS:<p>Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)</p>Fórmula:C4H4Na3O6PPureza:99.8% - ≥95%Cor e Forma:SolidPeso molecular:248.01SW033291
CAS:<p>SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.</p>Fórmula:C21H20N2OS3Pureza:97.26% - 99.02%Cor e Forma:SolidPeso molecular:412.593-Hydroxybenzaldehyde
CAS:<p>3-Hydroxybenzaldehyde is a compound useful in organic synthesis.</p>Fórmula:C7H6O2Pureza:99.60%Cor e Forma:DrypowderPeso molecular:122.126PGD-IN-S3
CAS:<p>6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).</p>Fórmula:C15H10O4Pureza:99.12%Cor e Forma:SolidPeso molecular:254.24Enasidenib
CAS:<p>Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential</p>Fórmula:C19H17F6N7OPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:473.38Enasidenib mesylate
CAS:<p>Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.</p>Fórmula:C20H21F6N7O4SPureza:99.86%Cor e Forma:SolidPeso molecular:569.48DS44960156
CAS:<p>DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.</p>Fórmula:C20H15NO5Pureza:99.13%Cor e Forma:SolidPeso molecular:349.34GSK1940029
CAS:<p>GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.</p>Fórmula:C18H16Cl2N4O2Pureza:99.48% - 99.49%Cor e Forma:SolidPeso molecular:391.25Triflupromazine
CAS:<p>Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.</p>Fórmula:C18H19F3N2SCor e Forma:SolidPeso molecular:352.42hDHODH-IN-2
CAS:<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Fórmula:C19H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:304.349Nitrophenide
CAS:<p>Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.</p>Fórmula:C12H8N2O4S2Pureza:99.78%Cor e Forma:SolidPeso molecular:308.33AGI-14100
CAS:<p>AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.</p>Fórmula:C29H22ClF4N5O3Pureza:99.91%Cor e Forma:SolidPeso molecular:599.96Epostane
CAS:<p>Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.</p>Fórmula:C22H31NO3Pureza:>99.99%Cor e Forma:SolidPeso molecular:357.49DHODH-IN-24
CAS:<p>DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].</p>Fórmula:C26H26N4Cor e Forma:SolidPeso molecular:394.51IMB-XMA0038
CAS:<p>IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.</p>Fórmula:C11H10N4O6Pureza:98.94% - 99.96%Cor e Forma:SolidPeso molecular:294.22BI-4924
CAS:<p>BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.</p>Fórmula:C21H20Cl2N2O6SPureza:99.55%Cor e Forma:SolidPeso molecular:499.36NCT-506
CAS:<p>NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).</p>Fórmula:C25H23FN4O3SPureza:98%Cor e Forma:SolidPeso molecular:478.54SCH-451659
CAS:<p>SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.</p>Fórmula:C30H39Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:544.56BI-135585
CAS:<p>BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.</p>Fórmula:C28H32N2O4Pureza:99.45% - 99.57%Cor e Forma:SolidPeso molecular:460.57CM026
CAS:<p>CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.</p>Fórmula:C22H30N6O4Cor e Forma:SolidPeso molecular:442.51ML387
CAS:<p>ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>Fórmula:C20H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:335.4
