Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 267 produtos de "Desidrogenase"
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AZD 4017
CAS:<p>AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).</p>Fórmula:C22H33N3O3SPureza:99.61%Cor e Forma:SolidPeso molecular:419.5815-PGDH-IN-1
CAS:<p>15-PGDH-IN-1: potent oral 15-PGDH inhibitor, IC50=3nM, useful for tissue repair research.</p>Fórmula:C24H22N4O2Cor e Forma:SolidPeso molecular:398.46GSK321
CAS:<p>GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.</p>Fórmula:C28H28FN5O3Pureza:99.73%Cor e Forma:SolidPeso molecular:501.55CHK-336
CAS:<p>CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluria</p>Fórmula:C24H20F2N4O4S2Cor e Forma:SolidPeso molecular:530.5715-PGDH-IN-2
CAS:<p>15-PGDH-IN-2 (Compound 2) is an inhibitor of 15-PGDH with an IC50 value of 0.274 nM. This compound is useful for research into hair loss, bone formation, gastric ulcer healing, and dermal wound healing [1].</p>Fórmula:C16H13NO3S2Cor e Forma:SolidPeso molecular:331.41hDHODH-IN-1
CAS:<p>hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.</p>Fórmula:C17H14N2O2Pureza:99.97%Cor e Forma:SolidPeso molecular:278.31YG1702
CAS:<p>YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.</p>Fórmula:C23H30N2O7SCor e Forma:SolidPeso molecular:478.56PF-915275
CAS:<p>PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.</p>Fórmula:C18H14N4O2SPureza:99.58% - 99.61%Cor e Forma:SolidPeso molecular:350.39Anticancer agent 121
CAS:<p>Anticancer agent 121, a human lactate dehydrogenase A (hLDHA) inhibitor, exhibits potent anticancer activities, suitable for use in anticancer research [1].</p>Fórmula:C19H18N2O3SCor e Forma:SolidPeso molecular:354.42MK-0736
CAS:<p>MK-0736 is a potent and selective 11β-HSD-1 inhibitor.</p>Fórmula:C23H30F3N3O2SCor e Forma:SolidPeso molecular:469.56HSD17B13-IN-3
CAS:<p>HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].</p>Fórmula:C22H21NO6S2Cor e Forma:SolidPeso molecular:459.54Tetrahydro-11-dehydrocorticosterone
CAS:<p>Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].</p>Fórmula:C21H32O4Cor e Forma:SolidPeso molecular:348.48DHODH-IN-22
CAS:<p>DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.</p>Fórmula:C21H21ClF4N6O5Cor e Forma:SolidPeso molecular:548.88DHODH-IN-14
CAS:<p>DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726.</p>Fórmula:C15H7F4N3O3Pureza:99.81%Cor e Forma:SolidPeso molecular:353.23IDH889
CAS:<p>IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).</p>Fórmula:C23H25FN6O2Pureza:≥98%Cor e Forma:SolidPeso molecular:436.48Anticancer agent 122
CAS:<p>Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use in</p>Fórmula:C18H15ClN2O2SCor e Forma:SolidPeso molecular:358.84KB-74935
CAS:<p>KB-74935: enzyme inhibitor, mineralocorticoid blocker, treats cholesterol, hypolipidemia, neurological issues, Alzheimer's.</p>Fórmula:C19H18ClF4N3O3SPureza:99.4%Cor e Forma:SolidPeso molecular:479.88ALDH2 modulator 1
CAS:<p>ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.</p>Fórmula:C18H18ClFN2O3Pureza:99.68%Cor e Forma:SoildPeso molecular:364.8CB29
CAS:<p>CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).</p>Fórmula:C15H15N3O5SPureza:99.36%Cor e Forma:SolidPeso molecular:349.36BI-3231
CAS:<p>BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.</p>Fórmula:C16H14F2N4O3SPureza:98.2%Cor e Forma:SolidPeso molecular:380.37
