Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 267 produtos de "Desidrogenase"
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CAY10566
CAS:<p>CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.</p>Fórmula:C18H17ClFN5O2Pureza:99.5% - 99.54%Cor e Forma:SolidPeso molecular:389.81Olutasidenib
CAS:<p>Olutasidenib (FT-2102), an IDH1 inhibitor (IC50: 21.2/114 nM), is studied for treating AML/MDS and can cross the blood-brain barrier.</p>Fórmula:C18H15ClN4O2Pureza:98.57%Cor e Forma:SolidPeso molecular:354.79LY 345899
CAS:<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Fórmula:C20H21N7O7Pureza:99.7%Cor e Forma:SolidPeso molecular:471.42MTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Fórmula:C26H21F6N2O5Cor e Forma:SolidPeso molecular:555.45LDHA-IN-3
CAS:<p>LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.</p>Fórmula:C13H9F3SePureza:99.71%Cor e Forma:SolidPeso molecular:301.17IGUANA-1 free base
CAS:<p>IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.</p>Fórmula:C26H24ClN3O2Cor e Forma:SolidPeso molecular:445.94CM121
CAS:<p>CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.</p>Fórmula:C24H17FN4O3SCor e Forma:SolidPeso molecular:460.48PDK-IN-1
CAS:<p>PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.</p>Fórmula:C20H16BrN7OCor e Forma:SolidPeso molecular:450.29WAY-311610
CAS:<p>WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.</p>Fórmula:C16H13F3N4O2Pureza:98.01%Cor e Forma:SolidPeso molecular:350.3MTHFD2-IN-1
<p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Fórmula:C24H21NO6Cor e Forma:SolidPeso molecular:419.43Necroptosis-IN-3
CAS:<p>Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.</p>Fórmula:C12H17NOSPureza:99.85%Cor e Forma:SoildPeso molecular:223.33hDHODH-IN-13
CAS:<p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>Cor e Forma:SoildAscochlorin A
CAS:<p>Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitor</p>Fórmula:C23H31ClO4Cor e Forma:SolidPeso molecular:406.95D-Lactate dehydrogenase
CAS:<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Cor e Forma:SolidMTHFD2-IN-2
<p>MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Fórmula:C22H18N4O5Cor e Forma:SolidPeso molecular:418.4MTHFD2-IN-4 sodium
<p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>Fórmula:C26H21F6N2NaO5Cor e Forma:SolidPeso molecular:578.44Octanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Fórmula:C29H49N7NaO17P3SCor e Forma:SolidPeso molecular:915.7111β-HSD1-IN-11
CAS:<p>11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13</p>Fórmula:C15H11F3O3SPureza:99.61%Cor e Forma:SoildPeso molecular:328.31DSM705
CAS:<p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>Fórmula:C19H19F3N6OCor e Forma:SolidPeso molecular:404.397SCD1 inhibitor-3
CAS:<p>SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.</p>Fórmula:C19H16FN7O2Pureza:99.5%Cor e Forma:SolidPeso molecular:393.37
