Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 289 produtos de "Desidrogenase"
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GSK1940029
CAS:GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.Fórmula:C18H16Cl2N4O2Pureza:99.48% - 99.49%Cor e Forma:SolidPeso molecular:391.25Triflupromazine
CAS:<p>Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.</p>Fórmula:C18H19F3N2SCor e Forma:SolidPeso molecular:352.42hDHODH-IN-2
CAS:<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Fórmula:C19H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:304.349Nitrophenide
CAS:Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.Fórmula:C12H8N2O4S2Pureza:99.78%Cor e Forma:SolidPeso molecular:308.33DHODH-IN-24
CAS:<p>DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].</p>Fórmula:C26H26N4Cor e Forma:SolidPeso molecular:394.51IMB-XMA0038
CAS:IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.Fórmula:C11H10N4O6Pureza:98.94% - 99.96%Cor e Forma:SolidPeso molecular:294.22BRD9185
CAS:BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.Fórmula:C23H21F6N3O2Pureza:98%Cor e Forma:SolidPeso molecular:485.42BI-4924
CAS:BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.Fórmula:C21H20Cl2N2O6SPureza:99.55%Cor e Forma:SolidPeso molecular:499.36DHODH-IN-21
CAS:<p>DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.</p>Fórmula:C20H19ClF4N6O4Cor e Forma:SolidPeso molecular:518.85DHODH-IN-12
CAS:DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Fórmula:C10H9N3O2Pureza:99.53%Cor e Forma:SolidPeso molecular:203.2BI-135585
CAS:BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.Fórmula:C28H32N2O4Pureza:99.45% - 99.57%Cor e Forma:SolidPeso molecular:460.5711β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Fórmula:C13H9F3N2OCor e Forma:SolidPeso molecular:266.22ALDH3A1-IN-2
CAS:ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.Fórmula:C11H14N2O3Cor e Forma:SolidPeso molecular:222.24Epostane
CAS:Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.Fórmula:C22H31NO3Pureza:>99.99%Cor e Forma:SolidPeso molecular:357.49DHODH-IN-3
CAS:DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Fórmula:C17H13ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:312.75TM-1
CAS:TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.Fórmula:C26H32N2O6Cor e Forma:SolidPeso molecular:468.54CM026
CAS:<p>CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.</p>Fórmula:C22H30N6O4Cor e Forma:SolidPeso molecular:442.51ASP3662
CAS:ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.Fórmula:C19H16ClF3N4O2Cor e Forma:SolidPeso molecular:424.8ML387
CAS:ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.Fórmula:C20H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:335.4NCT-506
CAS:NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).Fórmula:C25H23FN4O3SPureza:98%Cor e Forma:SolidPeso molecular:478.54
