Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 289 produtos de "Desidrogenase"
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Oxycinchophen
CAS:Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.Fórmula:C16H11NO3Pureza:98%Cor e Forma:SolidPeso molecular:265.26GW648495
CAS:GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.Fórmula:C16H13N5Pureza:98%Cor e Forma:SolidPeso molecular:275.31BVT-116429
CAS:BVT-116429 is an inhibitor of 11β-HSD1.Fórmula:C13H12F4N2OSPureza:98%Cor e Forma:SolidPeso molecular:320.31AGI-14100
CAS:<p>AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.</p>Fórmula:C29H22ClF4N5O3Pureza:99.91%Cor e Forma:SolidPeso molecular:599.96SCH-451659
CAS:SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.Fórmula:C30H39Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:544.56GA11
CAS:<p>GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.</p>Fórmula:C19H14N2Pureza:98%Cor e Forma:SolidPeso molecular:270.33DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Fórmula:C22H18ClF6N3O3Cor e Forma:SolidPeso molecular:521.84CM39
CAS:CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.Fórmula:C19H15FN4OSCor e Forma:SolidPeso molecular:366.41Nitrefazole
CAS:Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.Fórmula:C10H8N4O4Cor e Forma:SolidPeso molecular:248.1911β-HSD1-IN-10
CAS:11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitiveFórmula:C16H10F3NO2Cor e Forma:SolidPeso molecular:305.25AMG-221
CAS:AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.Fórmula:C14H22N2OSPureza:98%Cor e Forma:SolidPeso molecular:266.411β-HSD1-IN-6
CAS:11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).Fórmula:C21H19ClN4OCor e Forma:SolidPeso molecular:378.86hDHODH-IN-11
CAS:hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.Fórmula:C24H23N3O3Cor e Forma:SolidPeso molecular:401.46MEDS433
CAS:<p>MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.</p>Fórmula:C20H11F4N3O2Cor e Forma:SolidPeso molecular:401.3111β-HSD1-IN-12
CAS:<p>11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome</p>Fórmula:C19H27ClN2O3SPureza:99.68%Cor e Forma:SolidPeso molecular:398.95DHODH-IN-8
CAS:<p>DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).</p>Fórmula:C17H13ClN2O2Pureza:99.78%Cor e Forma:SolidPeso molecular:312.75RS6212
CAS:<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Fórmula:C20H22N4O3SCor e Forma:SolidPeso molecular:398.48UCK2 Inhibitor-2
CAS:UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.Fórmula:C28H23N3O4SPureza:98.76% - 99.25%Cor e Forma:SolidPeso molecular:497.57RORγt/DHODH-IN-2
CAS:<p>RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).</p>Fórmula:C25H30N4OSCor e Forma:SolidPeso molecular:434.6DHODH-IN-4
CAS:DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.Fórmula:C17H12Cl2N2O2Pureza:99.34%Cor e Forma:SolidPeso molecular:347.2
