AhR
O Receptor de Hidrocarbonetos Aromáticos (AhR) é um fator de transcrição ativado por ligantes que desempenha um papel crítico na regulação das respostas biológicas a contaminantes ambientais, como dioxinas. O AhR também está envolvido no metabolismo de xenobióticos e na regulação das respostas imunológicas, proliferação e diferenciação celular. A desregulação da sinalização do AhR está associada a várias doenças, incluindo câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma gama de inibidores de AhR para apoiar sua pesquisa em toxicologia, biologia do câncer e imunologia.
Foram encontrados 42 produtos de "AhR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Leflunomide
CAS:Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.Fórmula:C12H9F3N2O2Pureza:99.52% - 99.96%Cor e Forma:Off White Crystalline SolidPeso molecular:270.21Mexiletine hydrochloride
CAS:Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.Fórmula:C11H18ClNOPureza:99.88%Cor e Forma:White To Off-White SolidPeso molecular:215.72BAY 2416964
CAS:BAY 2416964 is a small molecule inhibitor that selectively targets aromatic receptor (AhR) and is commonly used in tumor research. Cost-effective and quality-assured.Fórmula:C18H18ClN5O3Pureza:99.15% - 99.85%Cor e Forma:SolidPeso molecular:387.82Ref: TM-T10270
1mg48,00€5mg85,00€10mg120,00€25mg235,00€50mg354,00€100mg567,00€200mg793,00€1mL*10mM (DMSO)87,00€Nimodipine
CAS:Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.Fórmula:C21H26N2O7Pureza:99.64% - 99.79%Cor e Forma:SolidPeso molecular:418.44GNF351
CAS:GNF351: Full AHR antagonist, inhibits DRE-dependent/independent activity, low toxicity, binds AHR (IC50: 62 nM).Fórmula:C24H25N7Pureza:98.43%Cor e Forma:SolidPeso molecular:411.5Ref: TM-T15410
1mg44,00€5mg94,00€10mg144,00€25mg283,00€50mg520,00€100mg700,00€200mg945,00€1mL*10mM (DMSO)105,00€Diosmin
CAS:Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.Fórmula:C28H32O15Pureza:97.90%Cor e Forma:Greyish-Yellow Or Light Yellow Hygroscopic PowderPeso molecular:608.54WAY-605471
CAS:WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.Fórmula:C14H15NO3S2Pureza:99.62%Cor e Forma:SolidPeso molecular:309.4Ref: TM-T9822
1mg109,00€2mg163,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.043,00€1mL*10mM (DMSO)235,00€KYN-101
CAS:KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.
Fórmula:C22H19FN6Pureza:98.35%Cor e Forma:SolidPeso molecular:386.43AHR Inhibitor I-103
CAS:AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.Fórmula:C21H17FN6Pureza:98.70%Cor e Forma:SoildPeso molecular:372.43',4'-Dimethoxyflavone
CAS:3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.Fórmula:C17H14O4Pureza:98.05%Cor e Forma:SolidPeso molecular:282.29StemRegenin 1 Hydrochloride
CAS:StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.Fórmula:C24H24ClN5OSPureza:99.94%Cor e Forma:SolidPeso molecular:466MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Fórmula:C17H12BrN3O2Pureza:99.64%Cor e Forma:SolidPeso molecular:370.2Ref: TM-T21966
1mg39,00€5mg74,00€10mg117,00€25mg220,00€50mg354,00€100mg520,00€500mg1.130,00€1mL*10mM (DMSO)86,00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Fórmula:C16H13NO3Pureza:98.63% - >99.99%Cor e Forma:Yellow SolidPeso molecular:267.28Ref: TM-T2623
5mg40,00€10mg52,00€25mg82,00€50mg106,00€100mg177,00€200mg264,00€500mg444,00€1mL*10mM (DMSO)58,00€Indole-3-pyruvic acid
CAS:Indole-3-pyruvic acid is a precursor for the plant growth hormone indole-3-acetic acid.Fórmula:C11H9NO3Pureza:98.89% - 99.21%Cor e Forma:Off White CrystalsPeso molecular:203.19VAF347
CAS:VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects.Fórmula:C17H11ClF3N3Pureza:98.75% - 99.55%Cor e Forma:SolidPeso molecular:349.74Ref: TM-T13276
1mg40,00€2mg51,00€5mg85,00€10mg119,00€25mg210,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)113,00€5-fluoro 203
CAS:5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts.Fórmula:C14H11FN2SPureza:97.61%Cor e Forma:SolidPeso molecular:258.31Ref: TM-T21704
5mg47,00€10mg67,00€25mg123,00€50mg182,00€100mg263,00€200mg374,00€1mL*10mM (DMSO)46,00€Indole-3-carbinol
CAS:Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFórmula:C9H9NOPureza:98.59% - >99.99%Cor e Forma:SolidPeso molecular:147.17Benzyl butyl phthalate
CAS:Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.Fórmula:C19H20O4Pureza:99.02%Cor e Forma:Colourless Liquid Oily LiquidPeso molecular:312.36FICZ
CAS:FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).Fórmula:C19H12N2OPureza:98.97%Cor e Forma:SolidPeso molecular:284.31Ref: TM-TQ0257
1mg49,00€5mg92,00€10mg138,00€25mg261,00€50mg442,00€100mg625,00€200mg892,00€1mL*10mM (DMSO)140,00€CH-223191
CAS:CH-223191, a specific aryl hydrocarbon receptor (AhR) antagonist, inhibited TCDD-induced luciferase activity with an IC50 of 0.03 μM. High-Quality, Low-Cost!Fórmula:C19H19N5OPureza:99.01% - 99.71%Cor e Forma:SolidPeso molecular:333.39L-Kynurenine
CAS:L-Kynurenine ((S)-Kynurenine)) is an endogenous agonist of aryl hydrocarbon receptor (AHR) ,inhibits allogeneic T cell proliferation. High-Quality, Low-Cost!Fórmula:C10H12N2O3Pureza:98.44% - 99.91%Cor e Forma:Light Yellow CrystallinePeso molecular:208.21BAY-218
CAS:Bindarit (AF2838) is an aryl hydrocarbon receptor (AHR) antagonist.Cost-effective and quality-assured.Fórmula:C20H17ClFN3O3Pureza:99.46% - 99.85%Cor e Forma:SolidPeso molecular:401.82Ref: TM-T5622
1mg40,00€2mg50,00€5mg72,00€10mg115,00€25mg250,00€50mg424,00€100mg630,00€500mg1.320,00€1mL*10mM (DMSO)79,00€Carbidopa
CAS:Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM).
Fórmula:C10H14N2O4Pureza:98.01% - ≥98%Cor e Forma:SolidPeso molecular:226.23Tapinarof
CAS:Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.Fórmula:C17H18O2Pureza:99.64% - >99.99%Cor e Forma:SolidPeso molecular:254.32PDM11
CAS:PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)Fórmula:C16H15ClO2Pureza:99.88%Cor e Forma:SolidPeso molecular:274.74ITE
CAS:ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.Fórmula:C14H10N2O3SPureza:97.91% - 99.14%Cor e Forma:SolidPeso molecular:286.31CAY 10465
CAS:CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).Fórmula:C15H9Cl2F3Pureza:98.80%Cor e Forma:SolidPeso molecular:317.13Ref: TM-T4607
1mg35,00€2mg52,00€5mg77,00€10mg110,00€25mg227,00€50mg430,00€100mg652,00€1mL*10mM (DMSO)86,00€Carbidopa monohydrate
CAS:Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.Fórmula:C10H16N2O5Pureza:98.11% - 98.30%Cor e Forma:SolidPeso molecular:244.24StemRegenin 1
CAS:StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.Fórmula:C24H23N5OSPureza:98% - 99.89%Cor e Forma:SolidPeso molecular:429.54PDM2
CAS:PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.Fórmula:C14H9Cl3Pureza:99.44%Cor e Forma:SolidPeso molecular:283.58Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Fórmula:C9H9NPureza:99.74%Cor e Forma:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecular:131.17Brevifolincarboxylic acid
CAS:Natural α-glucosidase inhibitor from Polygonum capitatum; blocks AhR with 323.46 μM IC50.Fórmula:C13H8O8Pureza:99.42% - 99.59%Cor e Forma:SolidPeso molecular:292.201,4-Chrysenequinone
CAS:1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR).Fórmula:C18H10O2Pureza:99.07% - 99.84%Cor e Forma:SolidPeso molecular:258.27Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Fórmula:C16H18N2OS·HBrPureza:97.71% - >99.99%Cor e Forma:SolidPeso molecular:367.3YL-109
CAS:YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.Fórmula:C14H11NO2SPureza:99.77% - ≥95%Cor e Forma:SolidPeso molecular:257.31Ref: TM-T1960
2mg35,00€5mg52,00€10mg80,00€25mg120,00€50mg188,00€100mg274,00€200mg406,00€500mg663,00€1mL*10mM (DMSO)52,00€DiMNF
CAS:Imigliptin (KBP 3853) is a dipeptidyl peptidase-4 inhibitor used in the study of type 2 diabetes.Fórmula:C21H16O4Pureza:97.60%Cor e Forma:SolidPeso molecular:332.35L-Kynurenine-d4
CAS:L-Kynurenine-d4 is a deuterated isotope compound of L-Kynurenine. L-Kynurenine is a metabolite of tryptophan and an endogenous agonist of the AHR.Fórmula:C10H8D4N2O3Cor e Forma:SolidPeso molecular:212.24D-Kynurenine
CAS:D-Kynurenine, ZINC901103, metabolizes from D-tryptophan, activates AhR, changes epithelium to mesenchyme, and tests for D-amino acid oxidase.Fórmula:C10H12N2O3Pureza:99.68%Cor e Forma:SolidPeso molecular:208.21Phortress
CAS:Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumorFórmula:C20H25Cl2FN4OSPureza:99.89%Cor e Forma:SolidPeso molecular:459.41Prochloraz
CAS:Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Fórmula:C15H16Cl3N3O2Pureza:99.75% - 99.79%Cor e Forma:Colorless SolidPeso molecular:376.67CAY10464
CAS:CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.Fórmula:C15H12Cl2OPureza:99.96%Cor e Forma:SolidPeso molecular:279.16AhR agonist 2
AhR agonist 2 is aryl hydrocarbon receptor (AhR) agonist,oral, inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair,psoriasis.Fórmula:C12H7Br2N3Cor e Forma:SolidPeso molecular:353.01
