Lipoxigenase
As lipoxigenases são uma família de enzimas que catalisam a oxigenação de ácidos graxos poli-insaturados, levando à produção de mediadores lipídicos bioativos, como os leucotrienos e as lipoxinas. Esses mediadores desempenham papéis críticos na inflamação, nas respostas imunes e no câncer. Inibidores de lipoxigenase são utilizados para estudar seu papel em doenças inflamatórias, asma e câncer. Na CymitQuimica, oferecemos uma variedade de inibidores de lipoxigenase para apoiar sua pesquisa em inflamação, oncologia e metabolismo lipídico.
Foram encontrados 134 produtos para "Lipoxigenase".
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AA 863
CAS:AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.Fórmula:C21H26O5Pureza:98%Cor e Forma:SolidPeso molecular:358.43Setileuton
CAS:Setileuton (MK0633) is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.Fórmula:C22H17F4N3O4Pureza:98.85% - 99.35%Cor e Forma:SolidPeso molecular:463.38Ref: TM-T34624
1mg177,00€5mg432,00€1mL*10mM (DMSO)537,00€10mg587,00€25mg892,00€50mg1.198,00€100mg1.575,00€200mg2.133,00€PXS-6302 hydrochloride
CAS:PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3Fórmula:C10H11ClF3NO2SPureza:99.98%Cor e Forma:SolidPeso molecular:301.71CCT365623
CAS:CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.Fórmula:C18H17NO4S3Pureza:97.29% - 97.63%Cor e Forma:White SolidPeso molecular:407.53Ref: TM-T26969
1mg86,00€5mg180,00€1mL*10mM (DMSO)225,00€10mg245,00€25mg374,00€50mg504,00€100mg662,00€200mg875,00€Lobaric acid
CAS:Lobaric acid, from Stereocaulon lichen, has antioxidant and anticancer properties, inhibits PTP1B and 12(S)-LOX, and reduces TMV lesions in plants.Fórmula:C25H28O8Cor e Forma:SolidPeso molecular:456.48L 691816
CAS:L 691816 is an effective inhibitor of the 5-LO reaction.Fórmula:C36H35ClN6OSPureza:98%Cor e Forma:SolidPeso molecular:635.22Resolvin E2
CAS:RvE2, a bioactive lipid from the SPM family, is made from EPA and reduces inflammatory neutrophil infiltration and helps treat NAFLD and other diseases.Fórmula:C20H30O4Cor e Forma:SolidPeso molecular:334.455-LOX/MAOs-IN-1
CAS:Compound 3, known as 5-LOX/MAOs-IN-1, acts as an inhibitor of 5-LOX/MAOs and is an effective free radical scavenger, displaying antioxidant characteristics. It has demonstrated neuroprotective effects in cell models damaged by oxidative stress and is capable of activating the neurogenesis microenvironment in adult mouse neural stem cells. This compound is utilized in research focused on neurodegenerative diseases.Fórmula:C18H18N2O2Cor e Forma:SolidPeso molecular:294.35h15-LOX-2 inhibitor 3
CAS:Compound 13, identified as h15-LOX-2 inhibitor 3, exhibits inhibitory activity against h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively.Fórmula:C22H13N5O3Cor e Forma:SolidPeso molecular:395.37WY-50295
CAS:WY-50295 is an orally active and selective 5-lipoxygenase inhibitor. In rat whole blood leukocytes, WY-50295 inhibits LTB4 formation with an IC50 of 40 μM and an oral ED50 of 18 mg/kg. WY-50295 is applicable for research into asthma and other leukotriene-dependent conditions.Fórmula:C23H19NO3Cor e Forma:SolidPeso molecular:357.40NCTT-956
CAS:NCTT-956 is a potent and specific inhibitor of platelet 12-lipoxygenase (12-LOX) activity.Fórmula:C17H15N3O4SPeso molecular:357.384ALOX15-IN-1
ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.Fórmula:C24H31N3O5SCor e Forma:SolidPeso molecular:473.59AZD 4407
CAS:AZD 4407 is a potent inhibitor of 5-lipoxygenase.Fórmula:C19H21NO3S2Pureza:98%Cor e Forma:SolidPeso molecular:375.5ALOX15-IN-2
CAS:ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.Fórmula:C23H29N3O4SPureza:99.98%Cor e Forma:SolidPeso molecular:443.56Ref: TM-T62606
1mg46,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg160,00€25mg313,00€50mg537,00€100mg767,00€500mg1.558,00€
