Lipoxigenase
As lipoxigenases são uma família de enzimas que catalisam a oxigenação de ácidos graxos poli-insaturados, levando à produção de mediadores lipídicos bioativos, como os leucotrienos e as lipoxinas. Esses mediadores desempenham papéis críticos na inflamação, nas respostas imunes e no câncer. Inibidores de lipoxigenase são utilizados para estudar seu papel em doenças inflamatórias, asma e câncer. Na CymitQuimica, oferecemos uma variedade de inibidores de lipoxigenase para apoiar sua pesquisa em inflamação, oncologia e metabolismo lipídico.
Foram encontrados 133 produtos de "Lipoxigenase"
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2-TEDC
CAS:2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.Fórmula:C16H13NO4SPureza:99.97%Cor e Forma:SolidPeso molecular:315.34LY 269415
CAS:LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.Fórmula:C19H28N2O2SCor e Forma:SolidPeso molecular:348.5Butibufen
CAS:Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.Fórmula:C14H20O2Pureza:98.11% - 98.91%Cor e Forma:SolidPeso molecular:220.315-LOX-IN-1
CAS:5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.
Fórmula:C20H18N2O2SPureza:97.45%Cor e Forma:SolidPeso molecular:350.43A-69412
CAS:A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.Fórmula:C7H10N2O3Pureza:99.54%Cor e Forma:SolidPeso molecular:170.17Ref: TM-T10208
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)188,00€Lonapalene
CAS:Lonapalene is a topically effective inhibitor of 5-lipoxygenase.Fórmula:C16H15ClO6Pureza:98.67% - 99.33%Cor e Forma:SolidPeso molecular:338.74Ref: TM-T16802
1mg100,00€2mg160,00€5mg290,00€10mg424,00€25mg642,00€50mg858,00€100mg1.153,00€200mg1.558,00€1mL*10mM (DMSO)318,00€A 78773
CAS:A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.Fórmula:C15H13FN2O4Cor e Forma:SolidPeso molecular:304.27MLS000545091
CAS:MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.Fórmula:C14H15ClN2OPureza:99.84%Cor e Forma:SolidPeso molecular:262.731-Stearoyl-2-Oleoyl-3-Linoleoyl-rac-glycerol
CAS:1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol is a triacylglycerol consisting of stearic acid, oleic acid, and linoleic acid esterified at the sn-1, sn-2, and sn-3 positions, respectively. This compound is present in peanut and soybean oils as well as in ostrich and emu oils. Additionally, it serves as a substrate for soybean lipoxygenase in cell-free assays.Fórmula:C57H104O6Cor e Forma:SolidPeso molecular:885.4317(S)-HpDHA
CAS:17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].Fórmula:C22H32O4Cor e Forma:SolidPeso molecular:360.49CMI-392
CAS:CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).Fórmula:C31H37ClN2O8SPureza:98%Cor e Forma:SolidPeso molecular:633.1515(S)-HEDE
CAS:15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 μM.Fórmula:C20H36O3Cor e Forma:SolidPeso molecular:324.5Benoxaprofen
CAS:Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.Fórmula:C16H12ClNO3Pureza:98.87%Cor e Forma:SolidPeso molecular:301.72Ref: TM-T19679
1mg202,00€5mg472,00€10mg707,00€25mg1.035,00€50mg1.311,00€100mg1.663,00€1mL*10mM (DMSO)469,00€TA-270
CAS:TA-720, a 5-lipoxygenase inhibitor, is used potentially for the treatment of asthma.Fórmula:C29H36N2O7Cor e Forma:SolidPeso molecular:524.61L 670630
CAS:L 670630 is a potent and orally active 5-lipoxygenase inhibitor.Fórmula:C25H26O3Pureza:98%Cor e Forma:SolidPeso molecular:374.47A 79175
CAS:A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.Fórmula:C15H13FN2O4Pureza:98%Cor e Forma:SolidPeso molecular:304.275-Lipoxygenase-In-1
CAS:5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.Fórmula:C23H28N4O2SCor e Forma:SolidPeso molecular:424.56h15-LOX-2 inhibitor 1
CAS:Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].Fórmula:C17H13F3N2SPureza:98%Cor e Forma:SolidPeso molecular:334.36(2E,9Z)-Octadeca-2,9-dienoic acid
CAS:(2E,9Z)-Octadeca-2,9-dienoic acid, a polyunsaturated fatty acid, is utilized in the study of lipoxygenase-dependent metabolism [1].Fórmula:C18H32O2Cor e Forma:SolidPeso molecular:280.455,6-dehydro Arachidonic Acid
CAS:5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.Fórmula:C20H30O2Cor e Forma:SolidPeso molecular:302.45
