Fosfolipase
As fosfolipases são um grupo de enzimas que hidrolisam fosfolipídios em ácidos graxos e outras substâncias lipofílicas, desempenhando um papel crítico na biologia das membranas e na geração de moléculas sinalizadoras. Inibidores de fosfolipases são usados para estudar seu papel em doenças inflamatórias, distúrbios cardiovasculares e neurodegeneração. Esses inibidores também são valiosos na exploração de vias de sinalização lipídica e suas implicações nos mecanismos de doenças. Na CymitQuimica, oferecemos uma variedade de inibidores de fosfolipases para apoiar sua pesquisa em inflamação, metabolismo lipídico e sinalização celular.
Foram encontrados 86 produtos para "Fosfolipase".
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Lp-PLA2-IN-1
CAS:Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.Fórmula:C21H17F5N4O3Pureza:99.60%Cor e Forma:White SolidPeso molecular:468.38Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Fórmula:C17H19N3O3SPureza:98.43% - 98.48%Cor e Forma:Brown SolidPeso molecular:345.42Lansoprazole
CAS:Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISONFórmula:C16H14F3N3O2SPureza:99.18% - 99.84%Cor e Forma:Yellow SolidPeso molecular:369.361Tris(2,4-di-tert-butylphenyl)phosphate
CAS:Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.Fórmula:C42H63O4PPureza:99.73%Cor e Forma:SolidPeso molecular:662.92ML349
CAS:ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM).Fórmula:C23H22N2O4S2Pureza:99.59% - 99.88%Cor e Forma:SolidPeso molecular:454.56nSMase2-IN-1
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.Fórmula:C12H17N5OPureza:98%Cor e Forma:SolidPeso molecular:247.3AACOCF3
CAS:AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.Fórmula:C21H31F3OPureza:99% - 99%Cor e Forma:SolidPeso molecular:356.47A3373
CAS:A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) ofFórmula:C17H9F7N2OPureza:98%Cor e Forma:SolidPeso molecular:390.26DPTIP
CAS:DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.Fórmula:C21H18N2O3SPureza:99.88%Cor e Forma:SolidPeso molecular:378.44Ref: TM-T60043
1mg46,00€2mg59,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg144,00€25mg281,00€50mg462,00€100mg672,00€Melittin Acetate
Melittin Acetate, a PLA2 activator, enhances low-weight PLA2 activity but not high-weight PLA2.Fórmula:C133H233N39O33Pureza:99.65%Cor e Forma:SolidPeso molecular:2906.51ASM-IN-3
CAS:ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.Fórmula:C17H13ClN2O4Cor e Forma:SolidPeso molecular:344.751,2-Bis(heptanoylthio)-sn-glycero-3-PG sodium
1,2-Bis(heptanoylthio)-sn-glycero-3-PG [1,2-Bis(heptanoylthio) glycerophosphatidylglycerol] sodium is a thioesterified phosphatidylglycerol derivative. It can be utilized to mimic phospholipase activity or serve as a probe molecule in membrane fusion studies.Cor e Forma:Odour SolidLEI110
CAS:LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.Fórmula:C25H23F3N2O3Pureza:98.66% - 99.01%Cor e Forma:SolidPeso molecular:456.46Compound 48/80 trihydrochloride
CAS:Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde produced via a condensation reaction.Fórmula:C32H48Cl3N3O3Pureza:98% - 99.24%Cor e Forma:White SolidPeso molecular:629.1VU533
CAS:VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.Fórmula:C21H22FN3O3S2Pureza:99.87%Cor e Forma:SolidPeso molecular:447.546PLA2-IN-1
PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.Cor e Forma:Odour Solid1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC
CAS:1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.Fórmula:C40H76NO8PCor e Forma:SolidPeso molecular:730.01A4333
A4333, a biotinylated derivative of A3373, selectively inhibits Phospholipase D1 (PLD1) while sparing PLD2.Pureza:98%Cor e Forma:Odour SolidsPLA2 inhibitor 2
sPLA2 inhibitor 2 (compound 6a) is an sPLA2 inhibitor with an IC50 value of 0.0475 μM, making it valuable for diabetes research.Fórmula:C20H18N6O4S2Cor e Forma:SolidPeso molecular:470.52SB-435495
CAS:SB-435495 is a compound characterized by its potent, selective, reversible, and non-covalent inhibition of Lp-PLA2, demonstrating an IC50 value of 0.06 nM.Fórmula:C38H40F4N6O2SPureza:99.58%Cor e Forma:White SolidPeso molecular:720.82
