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Fosfolipase

Fosfolipase

As fosfolipases são um grupo de enzimas que hidrolisam fosfolipídios em ácidos graxos e outras substâncias lipofílicas, desempenhando um papel crítico na biologia das membranas e na geração de moléculas sinalizadoras. Inibidores de fosfolipases são usados para estudar seu papel em doenças inflamatórias, distúrbios cardiovasculares e neurodegeneração. Esses inibidores também são valiosos na exploração de vias de sinalização lipídica e suas implicações nos mecanismos de doenças. Na CymitQuimica, oferecemos uma variedade de inibidores de fosfolipases para apoiar sua pesquisa em inflamação, metabolismo lipídico e sinalização celular.

Foram encontrados 82 produtos de "Fosfolipase"

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  • Omeprazole

    CAS:
    <p>Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.</p>
    Fórmula:C17H19N3O3S
    Pureza:98.43% - 98.48%
    Cor e Forma:White Solid
    Peso molecular:345.42
  • Niflumic acid

    CAS:
    <p>Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.</p>
    Fórmula:C13H9F3N2O2
    Pureza:99.47%
    Cor e Forma:Solid
    Peso molecular:282.22
  • Tris(2,4-di-tert-butylphenyl)phosphate

    CAS:
    <p>Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.</p>
    Fórmula:C42H63O4P
    Pureza:99.73%
    Cor e Forma:Solid
    Peso molecular:662.92
  • Lp-PLA2-IN-1

    CAS:
    <p>Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.</p>
    Fórmula:C21H17F5N4O3
    Pureza:99.60%
    Cor e Forma:Solid
    Peso molecular:468.38
  • Lansoprazole

    CAS:
    <p>Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON</p>
    Fórmula:C16H14F3N3O2S
    Pureza:99.18% - 99.84%
    Cor e Forma:White Crystalline Powder
    Peso molecular:369.36
  • ML349

    CAS:
    <p>ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM).</p>
    Fórmula:C23H22N2O4S2
    Pureza:99.59% - 99.88%
    Cor e Forma:Solid
    Peso molecular:454.56
  • 1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC

    CAS:
    <p>1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.</p>
    Fórmula:C40H76NO8P
    Cor e Forma:Solid
    Peso molecular:730.01
  • VU533

    CAS:
    <p>VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.</p>
    Fórmula:C21H22FN3O3S2
    Pureza:99.08%
    Cor e Forma:Solid
    Peso molecular:447.55
  • AACOCF3

    CAS:
    <p>AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.</p>
    Fórmula:C21H31F3O
    Pureza:99% - 99%
    Cor e Forma:Yellow Liquid
    Peso molecular:356.47
  • A3373

    CAS:
    <p>A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) of</p>
    Fórmula:C17H9F7N2O
    Pureza:98%
    Cor e Forma:Soild
    Peso molecular:390.26
  • Compound 48/80 trihydrochloride

    CAS:
    <p>Compound 48/80 trihydrochloride (C48/80 trihydrochloride) 是 N-甲基对甲氧基苯乙胺和甲醛发生缩合反应后的混合物。Compound 48/80 trihydrochloride 是一种肥大细胞 (mast cell) 脱颗粒剂和组胺 (histamine) 释放剂。Compound 48/80 trihydrochloride 对人血小板磷脂酰肌醇特异性磷脂酶 C (phosphatidylinositol-specific phospholipase C) 活性有抑制作用。</p>
    Fórmula:C32H48Cl3N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:629.1
  • ASM-IN-3

    CAS:
    <p>ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.</p>
    Fórmula:C17H13ClN2O4
    Cor e Forma:Solid
    Peso molecular:344.75
  • BIRM 271

    CAS:
    <p>BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.</p>
    Fórmula:C21H25N3O
    Pureza:99.64%
    Cor e Forma:Soild
    Peso molecular:335.44
  • SB-435495

    CAS:
    <p>SB-435495 is a compound characterized by its potent, selective, reversible, and non-covalent inhibition of Lp-PLA2, demonstrating an IC50 value of 0.06 nM.</p>
    Fórmula:C38H40F4N6O2S
    Pureza:99.07%
    Cor e Forma:Solid
    Peso molecular:720.82
  • DPTIP hydrochloride

    CAS:
    <p>DPTIP hydrochloride is a potent inhibitor of neutral sphingomyelinase (N-SMase 2) that can cross the blood-brain barrier. It acts as an exosome inhibitor with an IC50 value of 30 nM.</p>
    Fórmula:C21H19ClN2O3S
    Cor e Forma:Solid
    Peso molecular:414.91
  • PLA2-IN-1


    <p>PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.</p>
    Cor e Forma:Odour Solid
  • nSMase2-IN-1


    <p>nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.</p>
    Fórmula:C12H17N5O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:247.3
  • LEI110

    CAS:
    <p>LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.</p>
    Fórmula:C25H23F3N2O3
    Pureza:98.66% - 98.8%
    Cor e Forma:Solid
    Peso molecular:456.46
  • A4333


    <p>A4333, a biotinylated derivative of A3373, selectively inhibits Phospholipase D1 (PLD1) while sparing PLD2.</p>
    Pureza:98%
    Cor e Forma:Odour Solid
  • DPTIP

    CAS:
    <p>DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.</p>
    Fórmula:C21H18N2O3S
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:378.44
  • BMS493

    CAS:
    <p>BMS493 is an inverse agonist of RAR that inhibits retinoic acid-induced differentiation and inhibits the increase in phospholipase A2 activity.</p>
    Fórmula:C29H24O2
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:404.5
  • Bromoenol lactone

    CAS:
    <p>NeurokininBromoenol lactone ((6E)-Bromoenol lactone) is an iPLA2β and serine protease inhibitor that attenuates nicotine-induced breast cancer cell proliferation.</p>
    Fórmula:C16H13BrO2
    Cor e Forma:Solid
    Peso molecular:317.18
  • PACOCF3

    CAS:
    <p>PACOCF3, a phospholipase A2 inhibitor, hinders Ca2+ signaling with an IC50 of 3.8 μM in renal cells.</p>
    Fórmula:C17H31F3O
    Pureza:99.93%
    Cor e Forma:Solid
    Peso molecular:308.42
  • MJ33 lithium salt

    CAS:
    <p>MJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, inhibits PLA2 activity, and can be used to study acute lung injury.</p>
    Fórmula:C22H43F3LiO6P
    Pureza:99%
    Cor e Forma:Solid
    Peso molecular:498.48
  • LEI-401

    CAS:
    <p>LEI-401 is a NAPE-PLD inhibitor.LEI-401 reduces the level of n-acyl ethanolamines in the brain of free-ranging mice and modulates their emotional behaviour.</p>
    Fórmula:C24H31N5O2
    Pureza:99.79% - 99.79%
    Cor e Forma:Solid
    Peso molecular:421.54
  • ML-211

    CAS:
    <p>ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)</p>
    Fórmula:C25H30N4O2
    Pureza:97.07%
    Cor e Forma:Solid
    Peso molecular:418.53
  • N-(p-amylcinnamoyl) Anthranilic Acid

    CAS:
    <p>N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker.</p>
    Fórmula:C21H23NO3
    Pureza:99.35% - 99.67%
    Cor e Forma:Solid
    Peso molecular:337.41
  • Rhamnetin

    CAS:
    <p>Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities.</p>
    Fórmula:C16H12O7
    Pureza:99.61% - 99.905%
    Cor e Forma:Solid
    Peso molecular:316.26
  • hnps-PLA Inhibitor

    CAS:
    <p>Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).</p>
    Fórmula:C21H21N3O4
    Pureza:99.68%
    Cor e Forma:Solid
    Peso molecular:379.41
  • Varespladib

    CAS:
    <p>Varespladib (LY315920) inhibits hnsPLA2 effectively (IC50=7 nM), studied for sickle cell, VOC, and acute coronary syndrome.</p>
    Fórmula:C21H20N2O5
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:380.39
  • BAPTA

    CAS:
    <p>BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.</p>
    Fórmula:C22H24N2O10
    Pureza:96.28% - ≥95%
    Cor e Forma:White Solid
    Peso molecular:476.43
  • Rapanone

    CAS:
    <p>Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) is a natural benzoquinone that is a potent and selective inhibitor of human synovial PLA2.</p>
    Fórmula:C19H30O4
    Pureza:99.56%
    Cor e Forma:Solid
    Peso molecular:322.44
  • U-73343

    CAS:
    <p>U-73343 is an inactive analog of U-73122 and can be used as a negative control. U-73122 dose-dependently inhibits acid secretion irrespective of the stimulant.</p>
    Fórmula:C29H42N2O3
    Pureza:99.06%
    Cor e Forma:Solid
    Peso molecular:466.66
  • Tanshinone I

    CAS:
    <p>Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.</p>
    Fórmula:C18H12O3
    Pureza:98.31% - 98.70%
    Cor e Forma:Solid
    Peso molecular:276.29
  • ML348

    CAS:
    <p>ML348 (GNF-Pf-1127) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).</p>
    Fórmula:C18H17ClF3N3O3
    Pureza:99% - 99.88%
    Cor e Forma:Solid
    Peso molecular:415.79
  • FIPI

    CAS:
    <p>FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.</p>
    Fórmula:C23H24FN5O2
    Pureza:97.21% - 98.68%
    Cor e Forma:Solid
    Peso molecular:421.47
  • ML-298

    CAS:
    <p>ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM).</p>
    Fórmula:C22H23F3N4O2
    Pureza:99.35%
    Cor e Forma:Solid
    Peso molecular:432.44
  • 1-Naphthaleneacetic acid

    CAS:
    <p>1-Naphthaleneacetic acid, an auxin-like synthetic plant hormone, boosts rooting in horticulture.</p>
    Fórmula:C12H10O2
    Pureza:98.67%
    Cor e Forma:Needles From Water White To Off White Crystals
    Peso molecular:186.21
  • ST271

    CAS:
    <p>ST271 is an effective protein tyrosine kinase (PTK) inhibitor.</p>
    Fórmula:C16H20N2O2
    Pureza:98.94%
    Cor e Forma:Solid
    Peso molecular:272.34
  • Darapladib

    CAS:
    <p>Darapladib (SB-480848) is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with an IC50 value of 0.25 nM.Cost-effective and quality-assured.</p>
    Fórmula:C36H38F4N4O2S
    Pureza:99.82% - >99.99%
    Cor e Forma:Solid
    Peso molecular:666.77
  • RHC 80267

    CAS:
    <p>RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)</p>
    Fórmula:C20H34N4O4
    Pureza:99.54%
    Cor e Forma:White Solid
    Peso molecular:394.51
  • GW4869

    CAS:
    <p>GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM).</p>
    Fórmula:C30H30Cl2N6O2
    Pureza:98.12% - 98.47%
    Cor e Forma:Solid
    Peso molecular:577.5
  • RPI-1

    CAS:
    <p>RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.</p>
    Fórmula:C17H15NO4
    Pureza:98.91% - ≥95%
    Cor e Forma:Solid
    Peso molecular:297.31
  • 1-Linoleoyl Glycerol

    CAS:
    <p>1-Linoleoyl Glycerol (Monolinolein) is fatty acid glycerol that has been isolated from Saururus Chinensis roots.</p>
    Fórmula:C21H38O4
    Pureza:98.95% - 99.56%
    Cor e Forma:Less Oil Colourless Oil
    Peso molecular:354.52
  • ONO-RS-082

    CAS:
    <p>ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor. </p>
    Fórmula:C21H22ClNO3
    Pureza:99.35%
    Cor e Forma:Solid
    Peso molecular:371.86
  • AA26-9

    CAS:
    <p>AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.</p>
    Fórmula:C7H10N4O
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:166.18
  • 1-Naphthaleneacetic acid potassium salt

    CAS:
    <p>1-Naphthaleneacetic acid potassium salt (1-NAA Potassium Salt) is a synthetic phytogrowth hormone that promotes plant growth and a PLA2 inhibitor.</p>
    Fórmula:C12H9O2·K
    Pureza:97.68%
    Cor e Forma:Off-White To Beige Powder
    Peso molecular:224.3
  • Difluprednate

    CAS:
    <p>Difluprednate (Myser)(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.</p>
    Fórmula:C27H34F2O7
    Pureza:99.23% - 99.86%
    Cor e Forma:Solid
    Peso molecular:508.55
  • Cambinol

    CAS:
    <p>Cambinol is a SIRT1/2 inhibitor (IC50: 56/59 μM), non-competitive with NAD, weak on SIRT5, and prompts apoptosis in lymphoma cells.</p>
    Fórmula:C21H16N2O2S
    Pureza:98.02% - 99.83%
    Cor e Forma:Solid
    Peso molecular:360.43
  • CAY10594

    CAS:
    <p>CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.</p>
    Fórmula:C26H28N4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:428.53
  • trans-Benzylideneacetone

    CAS:
    <p>trans-Benzylideneacetone (Acetocinnamone) is used in various synthetic preparations.</p>
    Fórmula:C10H10O
    Pureza:97.48%
    Cor e Forma:Light Yellow Low Melting Crystalline Mass
    Peso molecular:146.19
  • Aristolochic acid C

    CAS:
    <p>Aristolochic acid C is a derivative of Aristolochic acid which is a phospholipase A2 inhibitor.</p>
    Fórmula:C16H9NO7
    Pureza:99.8%
    Cor e Forma:White Powder
    Peso molecular:327.25
  • CAY10650

    CAS:
    <p>CAY10650 is an effective inhibitor of cytosolic phospholipase A2α (cPLA2α, IC50: 12 nM).</p>
    Fórmula:C28H25NO6
    Pureza:97.33%
    Cor e Forma:Solid
    Peso molecular:471.5
  • U-73122

    CAS:
    <p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>
    Fórmula:C29H40N2O3
    Pureza:97.50%
    Cor e Forma:Solid Off-White
    Peso molecular:464.64
  • m-3M3FBS

    CAS:
    <p>m-3M3FBS is a phospholipase C (PLC) activator.</p>
    Fórmula:C16H16F3NO2S
    Pureza:99.66%
    Cor e Forma:Solid
    Peso molecular:343.36
  • Melittin

    CAS:
    <p>Melittin: principal bee venom toxin, 26 amino acids, activates low-weight PLA2, not high-weight PLA2.</p>
    Fórmula:C131H229N39O31
    Pureza:98.37% - 99.92%
    Cor e Forma:Solid
    Peso molecular:2846.46
  • Neomycin sulfate

    CAS:
    <p>Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert</p>
    Fórmula:C23H46N6O13·3H2SO4
    Pureza:99.4% - 99.88%
    Cor e Forma:Tan Powder
    Peso molecular:908.87
  • VU0155056

    CAS:
    <p>VU0155056 is a dual PLD1/2 inhibitor with IC50 &lt; 1 µM in cellular assays, inhibits breast cancer cell invasion.</p>
    Fórmula:C25H26N4O2
    Pureza:98.6% - 99.15%
    Cor e Forma:Solid
    Peso molecular:414.5
  • LCL521

    CAS:
    <p>LCL521 inhibits lysosomal acid sphingomyelinase (ASMase).LCL521 is an acid ceramidase (ACDase) inhibitor.</p>
    Fórmula:C31H52N4O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:592.77
  • Omeprazole Sodium

    CAS:
    <p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>
    Fórmula:C17H18N3NaO3S
    Pureza:99.84%
    Cor e Forma:Clear In Water
    Peso molecular:367.4
  • 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide

    CAS:
    <p>2-Decenoylaminoethyl cyclohexylethyl sulfide prevents stress ulcers, stabilizes phospholipase A2 and prostaglandin E2.</p>
    Fórmula:C20H37NOS
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:339.58
  • ML299

    CAS:
    <p>ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 nM, respectively).</p>
    Fórmula:C23H26BrFN4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:489.38
  • Lp-PLA2-IN-3

    CAS:
    <p>Lp-PLA2-IN-3: Potent oral inhibitor of human Lp-PLA2 with a 14 nM IC50.</p>
    Fórmula:C20H13ClF3N3O3S
    Pureza:99.65%
    Cor e Forma:Solid
    Peso molecular:467.85
  • ASM-IN-1

    CAS:
    <p>ASM-IN-1: Oral acid sphingomyelinase inhibitor, IC50 = 1.5 µM; reduces lipid plaques, plasma ceramide, Ox-LDL.</p>
    Fórmula:C16H12BrN3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:390.19
  • GK187

    CAS:
    <p>GK187 is a selective and potent Group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor, used in the study of neurological disorders.</p>
    Fórmula:C14H15F5O2
    Cor e Forma:Solid
    Peso molecular:310.26
  • Halopemide

    CAS:
    <p>Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2).</p>
    Fórmula:C21H22ClFN4O2
    Pureza:96.57%
    Cor e Forma:Solid
    Peso molecular:416.88
  • Giripladib

    CAS:
    <p>Giripladib (PLA695/PLX-695) blocks radiation-boosted phosphorylation of ERK and Akt in endothelial cells.</p>
    Fórmula:C41H36ClF3N2O4S
    Pureza:99.64%
    Cor e Forma:Solid
    Peso molecular:745.25
  • VU0155069

    CAS:
    <p>VU0155069, a selective PLD1 inhibitor (IC50: 46 nM), halts cancer cell migration in transwell assays.</p>
    Fórmula:C26H27ClN4O2
    Pureza:99.5%
    Cor e Forma:Solid
    Peso molecular:462.97
  • VU0364739

    CAS:
    <p>VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces cancer cell proliferation [1].</p>
    Fórmula:C26H27FN4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:446.52
  • Lp-PLA2-IN-13

    CAS:
    <p>Lp-PLA2-IN-13 (compound 15), a potent Lp-PLA2 inhibitor, holds potential for research in neurodegenerative-related diseases [1].</p>
    Fórmula:C22H17F5N4O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:496.39
  • Lp-PLA2-IN-2

    CAS:
    <p>Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.</p>
    Fórmula:C19H23FN2O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:394.46
  • Lp-PLA2-IN-14

    CAS:
    <p>Lp-PLA2-IN-14 (Compound 19), an inhibitor of rhLp-PLA2, exhibits a potent inhibitory effect with a pIC50 value of 8.4.</p>
    Fórmula:C16H14F3N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:353.3
  • 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid

    CAS:
    <p>7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA, 5 μM) significantly impacts the response to βA(25-35) stimulation. It reduces the formation of ROS.</p>
    Fórmula:C22H40O2
    Cor e Forma:Solid
    Peso molecular:336.55
  • Varespladib methyl

    CAS:
    <p>Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.</p>
    Fórmula:C22H22N2O5
    Pureza:99.42% - 99.97%
    Cor e Forma:Solid
    Peso molecular:394.42
  • Ecopladib

    CAS:
    <p>Ecopladib inhibits cPLA2α with IC50 of 0.15 μM (micelles) &amp; 0.11 μM (rat blood).</p>
    Fórmula:C39H33Cl3N2O5S
    Pureza:95.15%
    Cor e Forma:Solid
    Peso molecular:748.11
  • Rilapladib

    CAS:
    <p>Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating</p>
    Fórmula:C40H38F5N3O3S
    Pureza:99.92%
    Cor e Forma:Solid
    Peso molecular:735.8
  • MAFP

    CAS:
    <p>MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective irreversible inhibitor of anandamide amidase.</p>
    Fórmula:C21H36FO2P
    Cor e Forma:Solid
    Peso molecular:370.48
  • GK420

    CAS:
    <p>GK420 (AVX420) is a potent inhibitor of cytoplasmic phospholipase A2α (cPLA2α), with an XI(50) value of 0.0016. It effectively inhibits the release of arachidonic acid, with an EC50 of 0.09 μM. GK420 plays a significant role in cancer research.</p>
    Fórmula:C20H25NO5S
    Cor e Forma:Solid
    Peso molecular:391.481
  • Ro 23-9358

    CAS:
    <p>Ro 23-9358 is a potent inhibitor of secretory phospholipase A2, exhibiting anti-inflammatory properties.</p>
    Fórmula:C30H51NO6
    Cor e Forma:Solid
    Peso molecular:521.729
  • Lp-PLA2-IN-16

    CAS:
    <p>Lp-PLA2-IN-16 (Example 1) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential applications in Alzheimer's disease research [1].</p>
    Fórmula:C22H17F5N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:480.39

    Ref: TM-T79076

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  • Lp-PLA2-IN-12

    CAS:
    <p>Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease (AD), glaucoma, age-</p>
    Fórmula:C24H23F2N5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:467.47

    Ref: TM-T79010

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  • Lp-PLA2-IN-15

    CAS:
    <p>Lp-PLA2-IN-15 (example 2) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential application in Alzheimer's disease research [1].</p>
    Fórmula:C22H17F5N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:480.39

    Ref: TM-T79075

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