GlyT
Inibidores do Transportador de Glicina (GlyT) são compostos que bloqueiam a recaptação da glicina, um importante neurotransmissor inibitório na medula espinhal e no tronco encefálico. Ao inibir os transportadores de glicina, esses compostos aumentam a disponibilidade de glicina na fenda sináptica, aumentando seus efeitos inibitórios na atividade neuronal. Os inibidores de GlyT são de interesse por suas potenciais aplicações terapêuticas em condições como dor crônica, espasticidade e esquizofrenia. Na CymitQuimica, oferecemos inibidores de GlyT para apoiar sua pesquisa em manejo da dor, controle motor e transtornos neuropsiquiátricos.
Foram encontrados 27 produtos para "GlyT".
Filtrar por
Percentagem de pureza
0
100
|
0
|
50
|
90
|
95
|
100
- Preços em ordem crescente
- Preços em ordem decrescente
- Menor grau de pureza
- Maior grau de pureza
- Estimativa de entrega mais rápida
LY2365109 hydrochloride
CAS:LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.Fórmula:C22H28ClNO5Pureza:98.27%Cor e Forma:White SolidPeso molecular:421.91Iclepertin
CAS:Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.Fórmula:C20H18F6N2O5SPureza:99.21% - 99.66%Cor e Forma:SolidPeso molecular:512.423DCCCyb
CAS:DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.Fórmula:C22H29Cl2NO3SPureza:98%Cor e Forma:SolidPeso molecular:458.448-hydroxy Amoxapine
CAS:8-hydroxy Amoxapine is a metabolite of the tetracyclic antidepressant amoxapine .1,2Fórmula:C17H16ClN3O2Cor e Forma:SolidPeso molecular:329.78MPDC hydrochloride
MPDC hydrochloride is a competitive inhibitor of Na+-dependent, high-affinity glutamate transporters in forebrain synaptosomes.Fórmula:C7H10ClNO4Peso molecular:207.02984(Rac)-Oleoylcarnitine
CAS:(Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.Fórmula:C25H47NO4Peso molecular:425.65Org 24598 lithium salt
CAS:Org 24598 lithium salt is a GlyT-1 inhibitor of glycine transporter 1.Fórmula:C19H19F3LiNO3Cor e Forma:SolidPeso molecular:373.3SSR504734 HCl
CAS:SSR504734 inhibits GlyT1 in humans, rats, mice (IC50=18, 15, 38 nM); treats schizophrenia, anxiety, depression orally.Fórmula:C20H21Cl2F3N2OPureza:98.05% - 99.93%Cor e Forma:SolidPeso molecular:433.295Org 25543 hydrochloride
CAS:Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2).Fórmula:C24H33ClN2O4Pureza:99.26%Cor e Forma:White SolidPeso molecular:448.983Opiranserin hydrochloride
CAS:Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μMFórmula:C21H35ClN2O5Pureza:99.33%Cor e Forma:SolidPeso molecular:430.966Sarcosine
CAS:Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.Fórmula:C3H7NO2Pureza:99.90%Cor e Forma:SolidPeso molecular:89.0932SSR504734
CAS:SSR504734 is a novel potent glycine transporter 1 (GlyT1) inhibitor.Fórmula:C20H20ClF3N2OCor e Forma:SolidPeso molecular:396.83Bitopertin
CAS:Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nMFórmula:C21H20F7N3O4SPureza:98.57% - 98.71%Cor e Forma:SolidPeso molecular:543.455GSK931145
CAS:GSK931145 is a positron emission tomography (PET) radioligand, it is suitable for quantifying glycine transporter (GlyT1) availability in the living brain.Fórmula:C23H30N2OPureza:98%Cor e Forma:SolidPeso molecular:350.5PF-03463275
CAS:PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNSFórmula:C19H22ClFN4OPureza:99.95%Cor e Forma:SolidPeso molecular:376.856Tilapertin
CAS:Tilapertin is an oral glycine transporter type-1 inhibitor.Fórmula:C20H21F3N2O2Pureza:98%Cor e Forma:SolidPeso molecular:378.39Opiranserin
CAS:Opiranserin is a development as an injectable agent for the treatment of postoperative pain.Fórmula:C21H34N2O5Pureza:98%Cor e Forma:SolidPeso molecular:394.51ASP2535
CAS:ASP2535 is a potent, selective, orally bioavailable, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.ASP2535 can improve cognitiveFórmula:C22H18N6OPureza:98%Cor e Forma:SolidPeso molecular:382.42GlyT1 Inhibitor 1
CAS:GlyT1 Inhibitor 1 is a selective and potent GlyT1 inhibitor, inhibiting rGlyT1, used in research on neurological disorders.Fórmula:C22H21N5O2Cor e Forma:SolidPeso molecular:387.4344Org 24598
CAS:Potent GlyT1b inhibitor, IC50 = 6.9 nM; little effect on GlyT-2, adrenoceptors, dopamine, 5HT receptors, GABA transporters.Fórmula:C19H20F3NO3Cor e Forma:SolidPeso molecular:367.3622
