Beta Amilóide
Os inibidores de beta-amiloide são compostos que visam especificamente inibir a formação ou agregação de peptídeos beta-amiloides, que desempenham um papel crítico na patogênese da doença de Alzheimer. O acúmulo de placas de beta-amiloide no cérebro é uma característica marcante da doença, levando à disfunção neuronal e ao declínio cognitivo. Ao impedir a agregação de beta-amiloide, esses inibidores estão sendo explorados como potenciais agentes terapêuticos para retardar ou prevenir a progressão da doença de Alzheimer. Na CymitQuimica, oferecemos uma variedade de inibidores de beta-amiloide de alta qualidade para apoiar sua pesquisa em neurodegeneração, agregação de proteínas e terapia para Alzheimer.
Foram encontrados 205 produtos de "Beta Amilóide"
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JLK6
CAS:<p>JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signalling</p>Fórmula:C10H8ClNO3Pureza:96.50%Cor e Forma:SolidPeso molecular:225.63PBD-150
CAS:PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)Fórmula:C15H20N4O2SPureza:99.68%Cor e Forma:SolidPeso molecular:320.41CRANAD 2
CAS:<p>CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.</p>Fórmula:C23H25BF2N2O2Pureza:99.44%Cor e Forma:Dark Blue To Black PowderPeso molecular:410.271,1'-Methylenedi-2-naphthol
CAS:<p>1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).</p>Fórmula:C21H16O2Pureza:98.91%Cor e Forma:Light Pink To Light Brown Crystalline PowderPeso molecular:300.35Azeliragon HCl
CAS:<p>Azeliragon: potent oral RAGE inhibitor, blocks Alzheimer's-linked amyloid brain entry.</p>Fórmula:C32H40Cl3N3O2Cor e Forma:SolidPeso molecular:605.04Semagacestat
CAS:<p>Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).</p>Fórmula:C19H27N3O4Pureza:97.1% - 99.9%Cor e Forma:SolidPeso molecular:361.44FPS-ZM1
CAS:<p>FPS-ZM1 is a high-affinity RAGE specific inhibitor that blocks Aβ binding to the V domain of RAGE.</p>Fórmula:C20H22ClNOPureza:99.32% - 99.52%Cor e Forma:SolidPeso molecular:327.85Dihydroergocristine mesylate
CAS:<p>DHEC mesylate is a vasodilator and α-adrenergic antagonist used for vascular dementia and as a geroprotector.</p>Fórmula:C36H45N5O8SPureza:98.9% - 99.65%Cor e Forma:SolidPeso molecular:707.84Miridesap
CAS:<p>Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.</p>Fórmula:C16H24N2O6Pureza:≥95%Cor e Forma:SolidPeso molecular:340.37Pyridoxal 5'-phosphate hydrate
CAS:<p>Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,</p>Fórmula:C8H10NO6PPureza:97.52%Cor e Forma:SolidPeso molecular:247.14PiB
CAS:<p>PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.</p>Fórmula:C14H12N2OSPureza:97.02%Cor e Forma:SolidPeso molecular:256.32Cromoglicic acid
CAS:<p>Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.</p>Fórmula:C23H16O11Pureza:99.55% - >99.99%Cor e Forma:Colorless Crystals From Ethanol + Ether Physical Description Solid (Ntp 1992)Peso molecular:468.37Benzenesulfonamide
CAS:<p>Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.</p>Fórmula:C6H7NO2SPureza:99.42% - 99.99%Cor e Forma:White Crystalline PowderPeso molecular:157.19Semax acetate(80714-61-0 free base)
CAS:<p>Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.</p>Fórmula:C39H55N9O12SPureza:99.46%Cor e Forma:SolidPeso molecular:873.98Azeliragon
CAS:<p>Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-</p>Fórmula:C32H38ClN3O2Pureza:96.7% - 98.33%Cor e Forma:SolidPeso molecular:532.12ARN2966
CAS:<p>ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.</p>Fórmula:C12H12N2OPureza:99.52% - 99.86%Cor e Forma:SolidPeso molecular:200.24Edonerpic maleate
CAS:<p>Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).</p>Fórmula:C20H25NO6SPureza:98.24%Cor e Forma:SolidPeso molecular:407.48LX2343
CAS:<p>LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.</p>Fórmula:C22H19ClN2O6SPureza:99.45%Cor e Forma:SolidPeso molecular:474.91Aftin-4
CAS:<p>Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.</p>Fórmula:C20H28N6OPureza:98.51%Cor e Forma:SolidPeso molecular:368.48RO4929097
CAS:<p>RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).</p>Fórmula:C22H20F5N3O3Pureza:98.5% - 99.51%Cor e Forma:SolidPeso molecular:469.4
