Beta Amilóide
Os inibidores de beta-amiloide são compostos que visam especificamente inibir a formação ou agregação de peptídeos beta-amiloides, que desempenham um papel crítico na patogênese da doença de Alzheimer. O acúmulo de placas de beta-amiloide no cérebro é uma característica marcante da doença, levando à disfunção neuronal e ao declínio cognitivo. Ao impedir a agregação de beta-amiloide, esses inibidores estão sendo explorados como potenciais agentes terapêuticos para retardar ou prevenir a progressão da doença de Alzheimer. Na CymitQuimica, oferecemos uma variedade de inibidores de beta-amiloide de alta qualidade para apoiar sua pesquisa em neurodegeneração, agregação de proteínas e terapia para Alzheimer.
Foram encontrados 205 produtos de "Beta Amilóide"
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Buntanetap
CAS:<p>Buntanetap ((+)-Phenserine) is an inhibitor of TINAPs used in the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular disease</p>Fórmula:C20H23N3O2Pureza:98.2%Cor e Forma:SolidPeso molecular:337.42Glutaminyl Cyclase Inhibitor 1
CAS:Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.Fórmula:C21H24FN3O2Pureza:99.81%Cor e Forma:SolidPeso molecular:369.43Aβ-IN-1
CAS:<p>Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).</p>Fórmula:C35H49NPureza:99.1%Cor e Forma:SoildPeso molecular:483.77amyloid P-IN-1
CAS:<p>amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, and</p>Fórmula:C30H44N2O14Pureza:99.76%Cor e Forma:SolidPeso molecular:656.68Fenlean
CAS:<p>"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."</p>Fórmula:C26H27NO6Pureza:98.99%Cor e Forma:SolidPeso molecular:449.5Ezeprogind disulfate
CAS:<p>Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.</p>Fórmula:C25H48N6O8S2Pureza:99.72%Cor e Forma:SolidPeso molecular:624.81DSS30
CAS:<p>DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid secretion to help prevent Alzheimer's.</p>Fórmula:C16H14ClNO3S2Pureza:99.19% - 99.4%Cor e Forma:SolidPeso molecular:367.87MAO-B-IN-9
CAS:<p>MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.</p>Fórmula:C18H24N2O2Pureza:99.93%Cor e Forma:SolidPeso molecular:300.4BI-1408
CAS:<p>BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).</p>Fórmula:C22H23FN6Pureza:99.63%Cor e Forma:SolidPeso molecular:390.46MK-3328
CAS:<p>MK-3328, a potential Alzheimer's drug, binds β-Amyloid with strong affinity (IC50:10.5 nM) and may serve as a PET ligand to gauge plaque load.</p>Fórmula:C14H9FN4OPureza:99.70% - >99.99%Cor e Forma:SolidPeso molecular:268.25PPI-1019
CAS:<p>PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).</p>Fórmula:C36H54N6O5Pureza:95.16% - 98.16%Cor e Forma:SolidPeso molecular:650.85QM-FN-SO3
CAS:<p>QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].</p>Fórmula:C29H25N4NaO3S2Cor e Forma:SolidPeso molecular:564.65Anti-amyloid agent-1
CAS:<p>Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].</p>Fórmula:C21H17F3N2O3Cor e Forma:SolidPeso molecular:402.37PQM130
CAS:<p>PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.</p>Fórmula:C23H27NO4Pureza:98.73%Cor e Forma:SolidPeso molecular:381.46ELND007
CAS:<p>ELND007 is a Gamma secretase inhibitor.</p>Fórmula:C19H14F4N4O2SCor e Forma:SolidPeso molecular:438.4Aβ/tau aggregation-IN-3
CAS:<p>Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional</p>Fórmula:C23H22N4O3Cor e Forma:SolidPeso molecular:402.45TRV-1387
CAS:<p>TRV-1387, a benzofurazan derivative, inhibits the aggregation of tau and amyloid-β [1].</p>Fórmula:C23H25F3N4O2Cor e Forma:SolidPeso molecular:446.47BMS 433796
CAS:<p>BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.</p>Fórmula:C21H20F2N4O4Pureza:99.17%Cor e Forma:SolidPeso molecular:430.4RAGE/SERT-IN-1
CAS:<p>RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and</p>Fórmula:C38H41ClN4OSCor e Forma:SolidPeso molecular:637.28QR-0217
CAS:<p>QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.</p>Fórmula:C19H13NO3Cor e Forma:SolidPeso molecular:303.31
