Beta Amilóide
Os inibidores de beta-amiloide são compostos que visam especificamente inibir a formação ou agregação de peptídeos beta-amiloides, que desempenham um papel crítico na patogênese da doença de Alzheimer. O acúmulo de placas de beta-amiloide no cérebro é uma característica marcante da doença, levando à disfunção neuronal e ao declínio cognitivo. Ao impedir a agregação de beta-amiloide, esses inibidores estão sendo explorados como potenciais agentes terapêuticos para retardar ou prevenir a progressão da doença de Alzheimer. Na CymitQuimica, oferecemos uma variedade de inibidores de beta-amiloide de alta qualidade para apoiar sua pesquisa em neurodegeneração, agregação de proteínas e terapia para Alzheimer.
Foram encontrados 205 produtos de "Beta Amilóide"
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OAB-14
CAS:<p>OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.</p>Fórmula:C32H46N4O2Cor e Forma:SolidPeso molecular:518.73Caprospinol
CAS:<p>Caprospinol inhibits β-Amyloid (Aβ) protein neurotoxicity.</p>Fórmula:C33H52O4Pureza:98%Cor e Forma:SolidPeso molecular:512.76AZ4800
CAS:<p>AZD4800 is a gamma secretase modulators.</p>Fórmula:C24H29N5O3Cor e Forma:SolidPeso molecular:435.52RS-0466
CAS:<p>RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.</p>Fórmula:C17H17N5O2Pureza:98%Cor e Forma:SolidPeso molecular:323.35YIAD-0205
CAS:<p>YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familial</p>Fórmula:C26H16Br2ClN3Cor e Forma:SolidPeso molecular:565.69K 01-162
CAS:<p>K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.</p>Fórmula:C15H14BrNCor e Forma:SolidPeso molecular:288.18KMS88009
CAS:<p>KMS88009 is an amyloid-β aggregation inhibitor that acts by ameliorating neurodegenerative disorder.</p>Fórmula:C19H19NO2Cor e Forma:SolidPeso molecular:293.36Chrysamine G
CAS:<p>Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.</p>Fórmula:C26H16N4Na2O6Cor e Forma:SolidPeso molecular:526.416Glutaminyl Cyclase Inhibitor 2
CAS:<p>Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor (IC50: 1.23 μM).</p>Fórmula:C19H20FN3Pureza:98%Cor e Forma:SolidPeso molecular:309.38JNJ-40418677
CAS:<p>JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.</p>Fórmula:C26H22F6O2Pureza:98%Cor e Forma:SolidPeso molecular:480.44BChE-IN-8
CAS:<p>BChE-IN-8, compound 20, is a potent oral BChE inhibitor effective on eqBChE and hBChE, crosses blood-brain barrier, and may help in Alzheimer's research.</p>Fórmula:C18H12BrN7O2Cor e Forma:SolidPeso molecular:438.24BACE1/2-IN-1
CAS:<p>BACE1/2-IN-1 inhibits BACE1/2 with IC50s of 0.01μM/0.0053μM, has better permeability and lower Pgp efflux but reduced metabolic stability.</p>Fórmula:C21H31N5OSCor e Forma:SolidPeso molecular:401.57Antioxidant agent-2
CAS:<p>Antioxidant agent-2 (3c), BBB-permeable, selectively chelates metals; shows neuroprotection, fights liver damage in Alzheimer's research.</p>Fórmula:C23H26N2O7Cor e Forma:SolidPeso molecular:442.46SV5
CAS:<p>SV5: potent anti-Alzheimer's, protects SHSY-5Y from Aβ1-42 death, stable with optimal pharmacology in plasma, antioxidant, neuroprotective.</p>Fórmula:C21H30N2O4S2Cor e Forma:SolidPeso molecular:438.6γ-Secretase modulator 12
CAS:<p>γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM.</p>Fórmula:C25H23N3O2Cor e Forma:SolidPeso molecular:397.47AY1511
CAS:<p>AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].</p>Fórmula:C17H14O6Cor e Forma:SolidPeso molecular:314.29TML-6
CAS:<p>TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.</p>Fórmula:C30H37NO7Pureza:99.71%Cor e Forma:SolidPeso molecular:523.62BuChE-IN-2
CAS:<p>BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.</p>Fórmula:C28H20F4N6O3Cor e Forma:SolidPeso molecular:564.49Glutaminyl Cyclase Inhibitor 5
<p>Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) of</p>Fórmula:C22H30N6OCor e Forma:SolidPeso molecular:394.51Aleplasinin
CAS:<p>Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic</p>Fórmula:C28H27NO3Pureza:99.21%Cor e Forma:SolidPeso molecular:425.52
