COX
Os inibidores da ciclooxigenase (COX) são compostos que bloqueiam a atividade das enzimas COX, envolvidas na produção de prostaglandinas, mediadores chave da inflamação e dor. Em neurociências, os inibidores de COX são estudados por seu potencial em reduzir a neuroinflamação, que está implicada em várias doenças neurodegenerativas, como a doença de Alzheimer, Parkinson e esclerose múltipla. Ao inibir a COX, esses compostos podem ajudar a mitigar os processos inflamatórios no cérebro e proteger contra danos neuronais. Na CymitQuimica, oferecemos uma variedade de inibidores de COX para apoiar sua pesquisa em neuroinflamação, gestão da dor e doenças neurodegenerativas.
Foram encontrados 562 produtos de "COX"
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Pranoprofen
CAS:Fórmula:C15H13NO3Pureza:>98.0%(GC)(T)Cor e Forma:White to Light yellow powder to crystalPeso molecular:255.27Imatinib Mesylate
CAS:Fórmula:C29H31N7O·CH4O3SPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:589.722-Hydroxy Ibuprofen
CAS:<p>2-Hydroxy Ibuprofen is a metabolite of ibuprofen, applicable in biochemical experiments and drug synthesis research. Ibuprofen inhibits both COX-1 and COX-2.</p>Fórmula:C13H18O3Cor e Forma:SolidPeso molecular:222.28(S)-Ketorolac
CAS:<p>(S)-Ketorolac is a potent inhibitor of COX1 and COX2 enzyme, and is nonsteroidal anti-inflammatory agent.</p>Fórmula:C15H13NO3Cor e Forma:SolidPeso molecular:255.27Betamethasone Valerate
CAS:Fórmula:C27H37FO6Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:476.59Nimesulide D5
CAS:<p>Nimesulide D5 is a deuterium labeled Nimesulide. Nimesulide is a selective inhibitor OF COX-2(IC50s of 70 nM-70 μM)</p>Fórmula:C13H12N2O5SPureza:98%Cor e Forma:SolidPeso molecular:313.34Parecoxib
CAS:Fórmula:C19H18N2O4SPureza:>97.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:370.42Tepoxalin
CAS:<p>Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.</p>Fórmula:C20H20ClN3O3Pureza:99.94%Cor e Forma:SolidPeso molecular:385.84Tiaprofenic acid
CAS:<p>Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.</p>Fórmula:C14H12O3SPureza:99.51%Cor e Forma:SolidPeso molecular:260.31Macelignan
CAS:<p>Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus.</p>Fórmula:C20H24O4Pureza:98.01% - >99.99%Cor e Forma:SolidPeso molecular:328.4anemarsaponin B
CAS:<p>Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity</p>Fórmula:C45H74O18Pureza:99.06% - 99.81%Cor e Forma:SolidPeso molecular:903.06Hexahydrocurcumin
CAS:<p>Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.</p>Fórmula:C21H26O6Pureza:99.43% - 99.88%Cor e Forma:SolidPeso molecular:374.43Dehydroevodiamine
CAS:<p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>Fórmula:C19H15N3OPureza:99.54%Cor e Forma:SolidPeso molecular:301.34Rebamipide mofetil
CAS:<p>Rebamipide mofetil is an orally active prodrug of Rebamipide which is a mucoprotective agent.</p>Fórmula:C25H26ClN3O5Pureza:98.17%Cor e Forma:SolidPeso molecular:483.94Metyrosine
CAS:<p>Metyrosine: antihypertensive, tyrosine hydroxylase inhibitor, controls COX-2, lowers blood pressure.</p>Fórmula:C10H13NO3Pureza:98.68% - 99.72%Cor e Forma:SolidPeso molecular:195.22Ginsenoside Rg5
CAS:<p>Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.</p>Fórmula:C42H70O12Pureza:98% - 99.65%Cor e Forma:SolidPeso molecular:767γ-Tocopherol
CAS:<p>(+)-γ-Tocopherol ((+)-γ-Tocopherol) is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.</p>Fórmula:C28H48O2Pureza:99.31% - 99.39%Cor e Forma:Clear Viscous Pale Yellow Oil Which Oxidises And Darkens On Exposure To Air Or LightPeso molecular:416.68Iguratimod
CAS:<p>Iguratimod (T614) is a COX-2 inhibitor (IC50: 20 μM), does not affect COX-1, and inhibits MIF (IC50: 6.81 μM).</p>Fórmula:C17H14N2O6SPureza:99.93%Cor e Forma:White PowderPeso molecular:374.37Tolmetin sodium
CAS:<p>Tolmetin sodium is an NSAID, orally active COX inhibitor with IC50 of 0.35 μM (COX-1) and 0.82 μM (COX-2).</p>Fórmula:C15H14NNaO3Cor e Forma:SolidPeso molecular:279.271Ampiroxicam
CAS:<p>Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.</p>Fórmula:C20H21N3O7SPureza:97.27% - 99.2%Cor e Forma:PowderPeso molecular:447.46Bromfenac
CAS:<p>Bromfenac, a potent COX inhibitor, targets ocular inflammation with IC50s of 5.56 nM for COX-1 and 7.45 nM for COX-2.</p>Fórmula:C15H12BrNO3Cor e Forma:SolidPeso molecular:334.16Zaltoprofen
CAS:<p>Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.</p>Fórmula:C17H14O3SPureza:99.72%Cor e Forma:Off-White To Pale Yellow Crystalline SolidPeso molecular:298.36α-Humulene
CAS:<p>α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory</p>Fórmula:C15H24Pureza:97.18% - 97.18%Cor e Forma:LiquidPeso molecular:204.35Ginsenoside Rd
CAS:<p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>Fórmula:C48H82O18Pureza:99.13% - 99.92%Cor e Forma:SolidPeso molecular:947.15(±)-Catechin
CAS:<p>(±)-Catechin ((±)-Catechin hydrate) hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.</p>Fórmula:C15H14O6Pureza:98.46%Cor e Forma:White To Yellow PowderPeso molecular:290.27Mavacoxib
CAS:<p>Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity.</p>Fórmula:C16H11F4N3O2SPureza:99.90%Cor e Forma:SolidPeso molecular:385.34Choline Fenofibrate
CAS:<p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>Fórmula:C22H28ClNO5Pureza:98.82%Cor e Forma:SolidPeso molecular:421.91Tolmetin sodium dihydrate
CAS:<p>Tolmetin sodium dihydrate is an oral NSAID inhibiting COX-1 and COX-2, widely used in studies of prostaglandin synthesis and anti-inflammatory mechanisms.</p>Fórmula:C15H18NNaO5Pureza:99.57%Cor e Forma:Crystalline SolidPeso molecular:315.3Bromfenac Sodium
CAS:<p>Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID) and an orally available COX inhibitor, which has anti-inflammatory activity.</p>Fórmula:C15H11BrNO3·NaPureza:99.93%Cor e Forma:SolidPeso molecular:356.15Regaloside B
CAS:<p>Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric</p>Fórmula:C20H26O11Pureza:99.4% - 99.57%Cor e Forma:SolidPeso molecular:442.41α-Demethylnaproxen
CAS:<p>α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)</p>Fórmula:C13H12O3Pureza:97.57%Cor e Forma:Off-White SolidPeso molecular:216.23FR 122047
CAS:<p>FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM</p>Fórmula:C23H26ClN3O3SPureza:99.93%Cor e Forma:SolidPeso molecular:459.99Jaceosidin
CAS:<p>Jaceosidin: anti-oxidant, anti-inflammatory, anti-cancer, immunosuppressive; affects CYP1A2/UGT1A1/UGT1A7 metabolism.</p>Fórmula:C17H14O7Pureza:98.23% - 99.28%Cor e Forma:SolidPeso molecular:330.29Dexketoprofen trometamol
CAS:<p>Dexketoprofen trometamol is a modified non-selective COX inhibitor with a rapid onset of action that is available as both oral and parenteral formulations.</p>Fórmula:C20H25NO6Pureza:99.97% - 99.98%Cor e Forma:SolidPeso molecular:375.42Hamaudol
CAS:<p>Hamaudol, from Saposhnikovia divaricata, has pain-relief and anti-inflammatory effects, inhibits COX-1/COX-2 (0.30/0.57 mM).</p>Fórmula:C15H16O5Pureza:99.62%Cor e Forma:SolidPeso molecular:276.28Indomethacin heptyl ester
CAS:<p>Indomethacin heptyl ester is a non-selective inhibitor of both COX-1 and COX-2</p>Fórmula:C26H30ClNO4Pureza:99.86%Cor e Forma:SolidPeso molecular:455.97Harpagoside
CAS:<p>Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.</p>Fórmula:C24H30O11Pureza:99.71% - ≥95%Cor e Forma:White To Off-White PowderPeso molecular:494.49Suprofen
CAS:<p>Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic.</p>Fórmula:C14H12O3SPureza:99.23% - 99.33%Cor e Forma:SolidPeso molecular:260.31Chlorthenoxazine
CAS:<p>Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity.</p>Fórmula:C10H10ClNO2Pureza:99.64%Cor e Forma:SolidPeso molecular:211.6420(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Fórmula:C42H72O13Pureza:98.11% - 99.93%Cor e Forma:SolidPeso molecular:785.01Ginsenoside C-K
CAS:<p>Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.</p>Fórmula:C36H62O8Pureza:99.65% - 99.97%Cor e Forma:SolidPeso molecular:622.87NB-598 Maleate
CAS:<p>NB-598 Maleate is a competitive squalene epoxidase (SE) inhibitor.</p>Fórmula:C31H35NO5S2Pureza:98%Cor e Forma:SolidPeso molecular:565.74Haloperidol decanoate
CAS:<p>Haloperidol decanoate (KD 16), an antipsychotic, treats schizophrenia and mood disorders as an intramuscular ester.</p>Fórmula:C31H41ClFNO3Pureza:99.57% - 99.72%Cor e Forma:SolidPeso molecular:530.11syringaldehyde
CAS:<p>Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species, moderately inhibiting COX-2 activity.</p>Fórmula:C9H10O4Pureza:99.24%Cor e Forma:Light Yellow-Green To Brown Crystalline PowderPeso molecular:182.17Ibuprofen Piconol
CAS:<p>Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.</p>Fórmula:C19H23NO2Pureza:99.21%Cor e Forma:SolidPeso molecular:297.39EIPA
CAS:<p>EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.</p>Fórmula:C11H18ClN7OPureza:96.62% - 99.981%Cor e Forma:Off-White To Yellow SolidPeso molecular:299.76Crocin II
CAS:<p>Crocin II combats gastric and liver injuries, reduces inflammation, apoptosis, oxidative stress, and may lower lipid levels and have antidepressant effects.</p>Fórmula:C38H54O19Pureza:98% - 99.00%Cor e Forma:SolidPeso molecular:814.82β-Elemonic Acid
CAS:<p>β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.</p>Fórmula:C30H46O3Pureza:99.61% - 99.8%Cor e Forma:SolidPeso molecular:454.68Tryptanthrin
CAS:<p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>Fórmula:C15H8N2O2Pureza:99.64% - 99.94%Cor e Forma:SolidPeso molecular:248.24Polmacoxib
CAS:<p>Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.</p>Fórmula:C18H16FNO4SPureza:97.88%Cor e Forma:SolidPeso molecular:361.39
