COX
Os inibidores da ciclooxigenase (COX) são compostos que bloqueiam a atividade das enzimas COX, envolvidas na produção de prostaglandinas, mediadores chave da inflamação e dor. Em neurociências, os inibidores de COX são estudados por seu potencial em reduzir a neuroinflamação, que está implicada em várias doenças neurodegenerativas, como a doença de Alzheimer, Parkinson e esclerose múltipla. Ao inibir a COX, esses compostos podem ajudar a mitigar os processos inflamatórios no cérebro e proteger contra danos neuronais. Na CymitQuimica, oferecemos uma variedade de inibidores de COX para apoiar sua pesquisa em neuroinflamação, gestão da dor e doenças neurodegenerativas.
Foram encontrados 562 produtos de "COX"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
FPL 62064
CAS:<p>FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin</p>Fórmula:C16H15N3OPureza:98.79%Cor e Forma:SolidPeso molecular:265.31CAFESTOL
CAS:<p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>Fórmula:C20H28O3Pureza:97.06% - 99.08%Cor e Forma:SolidPeso molecular:316.43NS-398
CAS:<p>NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.</p>Fórmula:C13H18N2O5SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:314.36TFAP
CAS:<p>TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor</p>Fórmula:C13H10F3N3OPureza:99.87%Cor e Forma:SolidPeso molecular:281.23Revaprazan hydrochloride
CAS:<p>Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.</p>Fórmula:C22H24ClFN4Pureza:99.62% - 99.91%Cor e Forma:SolidPeso molecular:398.9Byakangelicol
CAS:<p>Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.</p>Fórmula:C17H16O6Pureza:98.78% - 99.55%Cor e Forma:SolidPeso molecular:316.31Pectolinarigenin
CAS:<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Fórmula:C17H14O6Pureza:98.67% - 99.88%Cor e Forma:SolidPeso molecular:314.29Compound Lup-20(29)-en-3-yl acetate
<p>Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.</p>Fórmula:C32H52O2Pureza:98%Cor e Forma:SolidPeso molecular:468.75N-tert-butyl-α-Phenylnitrone
CAS:<p>N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.</p>Fórmula:C11H15NOPureza:99.46% - 99.84%Cor e Forma:SolidPeso molecular:177.24CAY10404
CAS:<p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>Fórmula:C17H12F3NO3SPureza:99.02%Cor e Forma:SolidPeso molecular:367.34Tinoridine hydrochloride
CAS:<p>Tinoridine HCl is an NSAID that inhibits lipid peroxides and renin release, unlike indomethacin and corticosteroids.</p>Fórmula:C17H21ClN2O2SPureza:97.49%Cor e Forma:SolidPeso molecular:352.88Isofraxidin
CAS:<p>Isofraxidin combats leukemia, ALI, and inflammation by modulating ROS, COX-2, PGE2, TNF-α, and p38/ERK1/2 pathways.</p>Fórmula:C11H10O5Pureza:99.51% - ≥95%Cor e Forma:SolidPeso molecular:222.19Tolmetin
CAS:<p>Tolmetin (Tolectin) NSAID; acts as a cyclooxygenase inhibitor; classified as an anti-inflammatory.</p>Fórmula:C15H15NO3Pureza:99.74% - >99.99%Cor e Forma:Off-White Crystalline PowerPeso molecular:257.28[10]-Shogaol
CAS:<p>[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.</p>Fórmula:C21H32O3Pureza:97.64% - 98.65%Cor e Forma:SolidPeso molecular:332.48α-Spinasterol
CAS:<p>α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects.</p>Fórmula:C29H48OPureza:97.03% - 99.58%Cor e Forma:SolidPeso molecular:412.69Mofezolac
CAS:<p>Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000</p>Fórmula:C19H17NO5Pureza:99.29%Cor e Forma:SolidPeso molecular:339.34Firocoxib
CAS:<p>Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.</p>Fórmula:C17H20O5SPureza:99.84%Cor e Forma:SolidPeso molecular:336.4Parecoxib
CAS:<p>Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.</p>Fórmula:C19H18N2O4SPureza:99.71% - 99.78%Cor e Forma:SolidPeso molecular:370.42Tazofelone
CAS:<p>Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.</p>Fórmula:C18H27NO2SPureza:99.89%Cor e Forma:SolidPeso molecular:321.48(E)-Ethyl p-methoxycinnamate
CAS:<p>1. (E)-Ethyl p-methoxycinnamate (EPMC) is an anticarcinogenic agent. 2. (E)-Ethyl p-methoxycinnamate (EPMC) is a glutathion S tranferase inhibitor.</p>Fórmula:C12H14O3Pureza:97.43%Cor e Forma:SolidPeso molecular:206.24RK33
CAS:<p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>Fórmula:C23H20N6O3Pureza:99.04% - 99.72%Cor e Forma:SolidPeso molecular:428.44Cis-5-Dodecenoic Acid
CAS:<p>Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position.</p>Fórmula:C12H22O2Pureza:98% - 99.37%Cor e Forma:SolidPeso molecular:198.3Madecassic acid
CAS:<p>Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.</p>Fórmula:C30H48O6Pureza:98.80% - 99.69%Cor e Forma:SolidPeso molecular:504.7Gnetol
CAS:<p>Gnetol inhibits butyrylcholinesterase (IC50: 1.3 μM), tyrosinase, melanin synthesis in B16 cells, and AA-induced platelet aggregation.</p>Fórmula:C14H12O4Pureza:98.55% - ≥95%Cor e Forma:SolidPeso molecular:244.24Columbin
CAS:<p>Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.</p>Fórmula:C20H22O6Pureza:99.34% - 99.74%Cor e Forma:SolidPeso molecular:358.39S-(+)-Marmesin
CAS:<p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>Fórmula:C14H14O4Pureza:98.00% - ≥98%Cor e Forma:SolidPeso molecular:246.26Losartan Carboxaldehyde
CAS:<p>Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.</p>Fórmula:C22H21ClN6OPureza:99.1%Cor e Forma:SolidPeso molecular:420.89Esculentoside A
CAS:<p>Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.</p>Fórmula:C42H66O16Pureza:98% - 99.85%Cor e Forma:SolidPeso molecular:826.96Isoorientin
CAS:<p>Isoorientin (Homoorientin) has antioxidant activity.</p>Fórmula:C21H20O11Pureza:98.84% - 99.93%Cor e Forma:SolidPeso molecular:448.38Psoralidin
CAS:<p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>Fórmula:C20H16O5Pureza:98% - 99.61%Cor e Forma:SolidPeso molecular:336.342,5-Di-tert-butylhydroquinone
CAS:<p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>Fórmula:C14H22O2Pureza:97.11%Cor e Forma:PelletslargecrystalsPeso molecular:222.32(+)-Catechin Hydrate
CAS:<p>(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological</p>Fórmula:C15H16O7Pureza:99.03% - 99.96%Cor e Forma:SolidPeso molecular:308.28Chlorotrianisene
CAS:<p>Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.</p>Fórmula:C23H21ClO3Pureza:98.88% - 99.03%Cor e Forma:Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)Peso molecular:380.86Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Fórmula:C20H18O11Pureza:97.02% - 99.94%Cor e Forma:White PowderPeso molecular:434.35[8]-Shogaol
CAS:<p>[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.</p>Fórmula:C19H28O3Pureza:97.01%Cor e Forma:SolidPeso molecular:304.42Diclofenac Potassium
CAS:<p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>Fórmula:C14H10Cl2KNO2Pureza:99.51%Cor e Forma:White To Yellowish Crystalline PowderPeso molecular:334.24Lumiracoxib
CAS:<p>Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.</p>Fórmula:C15H13ClFNO2Pureza:96.64% - 99.77%Cor e Forma:Pale Yellow SolidPeso molecular:293.72(-)-Catechin gallate
CAS:<p>(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.</p>Fórmula:C22H18O10Pureza:97.74% - >99.99%Cor e Forma:SolidPeso molecular:442.37Adelmidrol
CAS:<p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Cor e Forma:SolidPeso molecular:274.367,3',4'-Tri-O-methylluteolin
CAS:<p>7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).</p>Fórmula:C18H16O6Pureza:98.66% - 99.79%Cor e Forma:SolidPeso molecular:328.32sphondin
CAS:<p>Sphondin inhibits IL-1beta, reduces COX-2 and PGE(2) in A549 cells, and has anticonvulsant, anti-inflammatory, anti-proliferative properties.</p>Fórmula:C12H8O4Pureza:99.9% - ≥95%Cor e Forma:SolidPeso molecular:216.19Ginsenoside Rb3
CAS:<p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>Fórmula:C53H90O22Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:1079.27SC-58125
CAS:<p>SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor. SC-58125 exhibits antitumor activity, and also inhibits oedema at sites of inflammation.</p>Fórmula:C17H12F4N2O2SPureza:99.57%Cor e Forma:SolidPeso molecular:384.35Roburic acid
CAS:<p>Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.</p>Fórmula:C30H48O2Pureza:98.765% - 99.88%Cor e Forma:SolidPeso molecular:440.7Tinoridine
CAS:<p>Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2).</p>Fórmula:C17H20N2O2SPureza:99.08%Cor e Forma:SolidPeso molecular:316.42FK 3311
CAS:<p>FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (</p>Fórmula:C15H13F2NO4SPureza:97.98%Cor e Forma:SolidPeso molecular:341.33Propyphenazone
CAS:<p>Propyphenazone: an anti-inflammatory, analgesic, antipyretic pyrazolone; prodrug; COX-2 inhibitor.</p>Fórmula:C14H18N2OPureza:99.64%Cor e Forma:SolidPeso molecular:230.31Teriflunomide impurity 3
CAS:<p>Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM).</p>Fórmula:C14H11F3N2OPureza:99.62%Cor e Forma:SolidPeso molecular:280.25Otenaproxesul
CAS:<p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>Fórmula:C21H19NO3SPureza:98.76% - 99.13%Cor e Forma:SolidPeso molecular:365.45Fenoprofen Calcium
CAS:<p>Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.</p>Fórmula:C30H26CaO6Pureza:99.24% - 99.66%Cor e Forma:SolidPeso molecular:522.6
![[10]-Shogaol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT5431.webp&w=3840&q=75)
![[8]-Shogaol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT5430.webp&w=3840&q=75)
