GluR
Inibidores do Receptor de Glutamato são compostos que bloqueiam a atividade dos receptores de glutamato, os principais receptores de neurotransmissores excitatórios no cérebro. Esses receptores desempenham um papel crucial na transmissão sináptica, plasticidade, aprendizado e memória. A desregulação da sinalização do glutamato está associada a vários distúrbios neurológicos, como epilepsia, AVC e doenças neurodegenerativas. Os inibidores dos receptores de glutamato são essenciais para investigar os mecanismos de excitotoxicidade e desenvolver estratégias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de receptores de glutamato para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.
Foram encontrados 265 produtos de "GluR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
γ-DGG acetate(6729-55-1 free base)
CAS:gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.Fórmula:C9H16N2O7Pureza:99.81%Cor e Forma:SolidPeso molecular:264.23NBQX disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Fórmula:C12H6N4Na2O6SPureza:97.32% - 97.6%Cor e Forma:SolidPeso molecular:380.2415AZD-8529 mesylate
CAS:AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).Fórmula:C25H28F3N5O6SPureza:99.19%Cor e Forma:SolidPeso molecular:583.58Ref: TM-T10432L
1mg57,00€5mg120,00€10mg188,00€25mg432,00€50mg747,00€100mg1.093,00€200mg1.454,00€1mL*10mM (DMSO)156,00€(R)-ADX-47273
CAS:(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).
Fórmula:C20H17F2N3O2Pureza:99.87%Cor e Forma:SolidPeso molecular:369.36(R)-3,4-DCPG HCl
(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal
Fórmula:C10H10ClNO6Pureza:98.80% - 99.89%Cor e Forma:SoildPeso molecular:275.64Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Fórmula:C11H12N2O2Pureza:99.67%Cor e Forma:SolidPeso molecular:204.23Decoglurant
CAS:Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.Fórmula:C21H11F6N5Pureza:99.77%Cor e Forma:SolidPeso molecular:447.34Ref: TM-T15090
1mg52,00€5mg111,00€10mg164,00€25mg294,00€50mg411,00€100mg572,00€200mg772,00€1mL*10mM (DMSO)152,00€Basimglurant
CAS:Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).Fórmula:C18H13ClFN3Pureza:98.35%Cor e Forma:SolidPeso molecular:325.77Ref: TM-T12717
1mg71,00€5mg152,00€10mg222,00€25mg358,00€50mg532,00€100mg665,00€200mg898,00€1mL*10mM (DMSO)167,00€DHPG
CAS:DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.Fórmula:C8H9NO4Pureza:99.55%Cor e Forma:SolidPeso molecular:183.16Piracetam
CAS:Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.Fórmula:C6H10N2O2Pureza:97.16%Cor e Forma:Crystals From Isopropanol SolidPeso molecular:142.16VU0650786
CAS:VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.Fórmula:C18H15ClFN5O2Pureza:99.09%Cor e Forma:SolidPeso molecular:387.8Ref: TM-T13318
1mg90,00€5mg222,00€10mg313,00€25mg530,00€50mg757,00€100mg1.044,00€1mL*10mM (DMSO)245,00€KM02894
CAS:KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.Fórmula:C7H9N3OS2Pureza:99.98%Cor e Forma:SolidPeso molecular:215.3LY339434 HCl
LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)Fórmula:C18H20ClNO4Pureza:97.10% - 97.19%Cor e Forma:SoildPeso molecular:349.81MMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Fórmula:C19H16ClN3O3Pureza:99.88%Cor e Forma:SolidPeso molecular:369.8Ref: TM-T23008L
1mg56,00€5mg119,00€10mg192,00€25mg394,00€50mg585,00€100mg833,00€200mg1.134,00€1mL*10mM (DMSO)133,00€mGluR3 modulator-1
CAS:1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.Fórmula:C16H21N3OPureza:98.99%Cor e Forma:SolidPeso molecular:271.36GYKI-47261 dihydrochloride
CAS:GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.
Fórmula:C18H17Cl3N4Pureza:98.32% - 99.14%Cor e Forma:SolidPeso molecular:395.71(±)-LY367385
CAS:(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.Fórmula:C10H11NO4Cor e Forma:SolidPeso molecular:209.201Pomaglumetad methionil anhydrous
CAS:LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.Fórmula:C12H18N2O7S2Pureza:98%Cor e Forma:SolidPeso molecular:366.41MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Fórmula:C8H8FNO5Cor e Forma:SolidPeso molecular:217.15MPPG
CAS:MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).Fórmula:C9H12NO5PCor e Forma:SolidPeso molecular:245.171LY2812223
CAS:LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Fórmula:C10H12N4O4SPureza:98%Cor e Forma:SolidPeso molecular:284.29VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
Fórmula:C20H10Cl3N3O3Pureza:99.61%Cor e Forma:SolidPeso molecular:446.67STX-107
CAS:STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.
Fórmula:C18H10FN3SPureza:99.17%Cor e Forma:SolidPeso molecular:319.36(S,S)-BMS-984923
CAS:(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Fórmula:C22H15ClN2O2Cor e Forma:SolidPeso molecular:374.82MGS0274
CAS:MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.Fórmula:C21H32FNO7Cor e Forma:SolidPeso molecular:429.485LY3027788
CAS:LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.Fórmula:C25H31F2NO11SCor e Forma:SolidPeso molecular:591.58DD205-291
CAS:DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.Fórmula:C38H38ClF3N10O3Cor e Forma:SolidPeso molecular:775.22(S)-3,4-DCPG HCl
(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.Fórmula:C10H10ClNO6Pureza:99.53% - 99.86%Cor e Forma:SoildPeso molecular:275.64Ref: TM-T23288L
1mg183,00€5mg462,00€10mg660,00€25mg1.035,00€50mg1.415,00€100mg1.872,00€500mg3.763,00€1mL*10mM (DMSO)415,00€KRP-199 sodium
KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.Fórmula:C22H12F3N5Na2O7Pureza:97.27%Cor e Forma:SoildPeso molecular:561.33mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Fórmula:C18H19ClFN3O2Cor e Forma:SolidPeso molecular:363.82LY3020371
CAS:LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.Fórmula:C15H15F2NO5SCor e Forma:SolidPeso molecular:359.341H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.
Fórmula:C10H12N2O2SPureza:99.96%Cor e Forma:SoildPeso molecular:224.28L-AP3
CAS:L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).Fórmula:C3H8NO5PCor e Forma:White Hygroscopic SolidPeso molecular:169.073(S)-3,4-DCPG
CAS:(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Fórmula:C10H9NO6Pureza:98%Cor e Forma:SolidPeso molecular:239.18JF-NP-26
Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.Cor e Forma:SolidLY3027788 hydrochloride
CAS:LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.Fórmula:C25H32ClF2NO11SCor e Forma:SolidPeso molecular:628.03(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Fórmula:C7H11ClN2O4Pureza:99.18%Cor e Forma:SolidPeso molecular:222.63ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.Fórmula:C19H15FN2OPureza:99.98% - 99.98%Cor e Forma:SoildPeso molecular:306.33Ref: TM-T67917
5mg49,00€10mg79,00€25mg120,00€50mg164,00€100mg230,00€200mg314,00€1mL*10mM (DMSO)52,00€NS-102
CAS:NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.Fórmula:C12H11N3O4Pureza:98.48% - 98.95%Cor e Forma:SolidPeso molecular:261.23VU0422288
CAS:VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.Fórmula:C17H11Cl2N3O2Pureza:99.77%Cor e Forma:SolidPeso molecular:360.19LY487379
CAS:LY487379: human mGluR2 PAM, boosts glutamate binding, aids cognitive flexibility, may treat schizophrenia. EC50: 1.7 μM (mGlu2), >10 μM (mGlu3).Fórmula:C21H19F3N2O4SCor e Forma:SolidPeso molecular:452.45JNJ-46778212
CAS:JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.Fórmula:C20H17FN2O3Pureza:99.24%Cor e Forma:SolidPeso molecular:352.36Ro 01-6128
CAS:Positive allosteric modulator of mGlu1 receptorsFórmula:C17H17NO3Pureza:98%Cor e Forma:SolidPeso molecular:283.32AMN082
CAS:AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.Fórmula:C28H30Cl2N2Pureza:97.13% - 98.63%Cor e Forma:SolidPeso molecular:465.46VU0364770 hydrochloride
CAS:VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).Fórmula:C12H10Cl2N2OPureza:98%Cor e Forma:SolidPeso molecular:269.13LY341495
CAS:LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological disorders.Fórmula:C20H19NO5Pureza:98.53% - 99.37%Cor e Forma:SolidPeso molecular:353.37γ-DGG
CAS:gamma-DGG is a competitive blocker of AMPA receptor.Fórmula:C7H12N2O5Pureza:98%Cor e Forma:SolidPeso molecular:204.18GYKI 52466 dihydrochloride
CAS:GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.Fórmula:C17H17Cl2N3O2Pureza:99.38%Cor e Forma:SolidPeso molecular:366.24GYKI 53655 hydrochloride
CAS:GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.Fórmula:C19H21ClN4O3Pureza:98.02%Cor e Forma:SolidPeso molecular:388.85EGLU
CAS:EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.Fórmula:C7H13NO4Pureza:99.98%Cor e Forma:SolidPeso molecular:175.18CFMTI
CAS:CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.Fórmula:C19H16FN5OPureza:97.23%Cor e Forma:SolidPeso molecular:349.36Ref: TM-T3482
1mg57,00€2mg82,00€5mg120,00€10mg170,00€25mg304,00€50mg432,00€100mg602,00€1mL*10mM (DMSO)133,00€(S)-ATPO
CAS:(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
Fórmula:C11H19N2O7PPureza:98.37% - 99.41%Cor e Forma:SolidPeso molecular:322.25Chelidamic acid
CAS:Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.Fórmula:C7H5NO5Pureza:98.11%Cor e Forma:Pale Yellow PowderPeso molecular:183.12FTIDC
CAS:FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.Fórmula:C18H23FN6OPureza:94.58%Cor e Forma:SolidPeso molecular:358.41Ref: TM-T3483
1mg105,00€2mg154,00€5mg227,00€10mg359,00€25mg597,00€50mg842,00€100mg1.130,00€1mL*10mM (DMSO)250,00€VU-29
CAS:VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes.Fórmula:C22H16N4O3Pureza:99.63%Cor e Forma:SolidPeso molecular:384.39Ref: TM-T23515
2mg33,00€5mg50,00€10mg86,00€25mg161,00€50mg259,00€100mg371,00€200mg530,00€1mL*10mM (DMSO)55,00€JNJ16259685
CAS:JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19Fórmula:C20H23NO3Pureza:98.31%Cor e Forma:SolidPeso molecular:325.4Ref: TM-T5512
1mg46,00€2mg62,00€5mg95,00€10mg133,00€25mg278,00€50mg424,00€100mg620,00€1mL*10mM (DMSO)95,00€DNQX
CAS:DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
Fórmula:C8H4N4O6Pureza:97.27% - 99.1%Cor e Forma:Off-White Powder With A Yellow TingePeso molecular:252.14Farampator
CAS:Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.Fórmula:C12H13N3O2Pureza:99.84% - >99.99%Cor e Forma:SolidPeso molecular:231.25VU0361737
CAS:VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.Fórmula:C13H11ClN2O2Pureza:99.60% - 99.85%Cor e Forma:SolidPeso molecular:262.69(RS)-3-Hydroxyphenylglycine
CAS:(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.Fórmula:C8H9NO3Pureza:99.29%Cor e Forma:SolidPeso molecular:167.16PHCCC
CAS:PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.Fórmula:C17H14N2O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:294.3E4CPG
CAS:E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG.Fórmula:C11H13NO4Pureza:99.96%Cor e Forma:SolidPeso molecular:223.23CX614
CAS:CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.Fórmula:C13H13NO4Pureza:97.37%Cor e Forma:SolidPeso molecular:247.25Ref: TM-T19698
5mg52,00€10mg78,00€25mg119,00€50mg172,00€100mg259,00€200mg388,00€1mL*10mM (DMSO)55,00€ADX-47273
CAS:ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).Fórmula:C20H17F2N3O2Pureza:97% - 99.18%Cor e Forma:SolidPeso molecular:369.36ADX88178
CAS:ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.Fórmula:C12H12N6SPureza:99.55%Cor e Forma:SolidPeso molecular:272.33Ref: TM-T4500
2mg35,00€5mg55,00€10mg92,00€25mg147,00€50mg230,00€100mg335,00€200mg479,00€1mL*10mM (DMSO)57,00€AZD-8529
CAS:AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.Fórmula:C24H24F3N5O3Cor e Forma:SolidPeso molecular:487.47XAP044
CAS:XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.Fórmula:C15H9IO4Pureza:97.41%Cor e Forma:SolidPeso molecular:380.13Ref: TM-T21995
1mg58,00€2mg82,00€5mg107,00€10mg197,00€25mg350,00€50mg528,00€100mg755,00€1mL*10mM (DMSO)146,00€NBQX
CAS:NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.Fórmula:C12H8N4O6SPureza:97.66% - 99.93%Cor e Forma:SolidPeso molecular:336.28Ref: TM-T4113
1mg38,00€2mg50,00€5mg84,00€10mg114,00€25mg222,00€50mg334,00€100mg497,00€200mg717,00€1mL*10mM (DMSO)92,00€(RS)-MCPG
CAS:(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.Fórmula:C10H11NO4Pureza:99.96%Cor e Forma:SolidPeso molecular:209.2Ro 67-7476
CAS:Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors.Fórmula:C17H18FNO2SPureza:99.69%Cor e Forma:SolidPeso molecular:319.39Ref: TM-T3478
1mg34,00€2mg48,00€5mg88,00€10mg124,00€25mg244,00€50mg442,00€100mg643,00€1mL*10mM (DMSO)78,00€CTEP
CAS:CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-foldFórmula:C19H13ClF3N3OPureza:99.17%Cor e Forma:SolidPeso molecular:391.77Ref: TM-T6457
2mg37,00€5mg52,00€10mg93,00€25mg145,00€50mg256,00€100mg349,00€200mg495,00€1mL*10mM (DMSO)58,00€MPEP hydrochloride
CAS:MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).
Fórmula:C14H12ClNPureza:99.87% - >99.99%Cor e Forma:SolidPeso molecular:229.7(S)-3-Hydroxyphenylglycine
CAS:(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).Fórmula:C8H9NO3Pureza:99.65%Cor e Forma:SolidPeso molecular:167.16TAT-GluA2 3Y acetate(1404188-93-7 free base)
TAT-GluA2 3Y acetate is an inhibitor of AMPA receptor endocytosis.Systemic administration of Tat-GluA2(3Y) during the induction phase of d-amphetamine blockedFórmula:C115H185N43O29Pureza:99.43%Cor e Forma:SolidPeso molecular:2634.02SIB-1757
CAS:SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)Fórmula:C12H11N3OPureza:97.37%Cor e Forma:SolidPeso molecular:213.24MTEP hydrochloride
CAS:MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)Fórmula:C11H9ClN2SPureza:99.58%Cor e Forma:SolidPeso molecular:236.72HBT1
CAS:HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neuronsFórmula:C16H17F3N4O2SPureza:99.52%Cor e Forma:SolidPeso molecular:386.391-BCP
CAS:1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.Fórmula:C13H15NO3Pureza:99.60%Cor e Forma:SolidPeso molecular:233.26Lu AF21934
CAS:Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).
Fórmula:C14H16Cl2N2O2Pureza:99.79%Cor e Forma:SolidPeso molecular:315.2trans-ACPD
CAS:trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.Fórmula:C7H11NO4Pureza:99.53%Cor e Forma:SolidPeso molecular:173.17Ref: TM-T3484
1mg48,00€2mg63,00€5mg89,00€10mg147,00€25mg279,00€50mg505,00€100mg730,00€1mL*10mM (DMSO)74,00€IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Fórmula:C8H9ClN2O2SPureza:99.73%Cor e Forma:SolidPeso molecular:232.69LY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFórmula:C19H22N2O2SPureza:99.34%Cor e Forma:SolidPeso molecular:342.46Ref: TM-T7706
2mg35,00€5mg52,00€10mg90,00€25mg164,00€50mg239,00€100mg339,00€200mg472,00€1mL*10mM (DMSO)58,00€VU-1545
CAS:VU-1545 is mGlu5 positive allosteric modulator.Fórmula:C22H15FN4O3Pureza:98.8%Cor e Forma:SolidPeso molecular:402.38Ro0711401
CAS:Ro0711401 is an agonist of mGlu1 receptor.Fórmula:C18H11F3N2O3Pureza:97.57%Cor e Forma:SolidPeso molecular:360.29VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Fórmula:C17H17F2NO2Pureza:99% - >99.99%Cor e Forma:SolidPeso molecular:305.32YM90K
CAS:YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.Fórmula:C11H8ClN5O4Pureza:98.23%Cor e Forma:SolidPeso molecular:309.66Ref: TM-T8435
1mg73,00€5mg160,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€1mL*10mM (DMSO)170,00€VU0364770
CAS:VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGluFórmula:C12H9ClN2OPureza:99.65% - >99.99%Cor e Forma:SolidPeso molecular:232.67FITM
CAS:FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).Fórmula:C18H18FN5OSPureza:97.25%Cor e Forma:SolidPeso molecular:371.43Ref: TM-T7292
1mg34,00€2mg44,00€5mg66,00€10mg92,00€25mg177,00€50mg268,00€100mg394,00€1mL*10mM (DMSO)62,00€AMN082 free base
CAS:AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.Fórmula:C28H28N2Pureza:97.75% - 97.79%Cor e Forma:SolidPeso molecular:392.54Ref: TM-T21935L
5mg50,00€10mg74,00€25mg135,00€50mg212,00€100mg340,00€200mg475,00€1mL*10mM (DMSO)52,00€MPEP
CAS:MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.Fórmula:C14H11NPureza:99.54%Cor e Forma:SolidPeso molecular:193.24pep2-SVKI acetate
Pep2-SVKI acetate(pep2-SVKI acetate (328944-75-8 free base)) is a synthetic peptide salt that prevents internalization of AMPA-type glutamate receptor.Fórmula:C62H97N13O20Pureza:97.14%Cor e Forma:SolidPeso molecular:1344.51TCN238
CAS:TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).Fórmula:C12H11N3Pureza:99.9% - 99.92%Cor e Forma:SolidPeso molecular:197.24CNQX
CAS:CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)Fórmula:C9H4N4O4Pureza:99.70%Cor e Forma:Pale Yellow SolidPeso molecular:232.15MTEP
CAS:MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.Fórmula:C11H8N2SCor e Forma:SolidPeso molecular:200.26CX516
CAS:CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.Fórmula:C14H15N3OPureza:99.04% - ≥95%Cor e Forma:Tan SolidPeso molecular:241.293-MATIDA
CAS:3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).Fórmula:C8H9NO4SPureza:99.75% - 99.96%Cor e Forma:SolidPeso molecular:215.23Ref: TM-T3486
2mg34,00€5mg49,00€10mg79,00€25mg145,00€50mg227,00€100mg339,00€200mg482,00€1mL*10mM (DMSO)49,00€VU0155094
CAS:VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.
Fórmula:C24H24N2O4SPureza:97.21%Cor e Forma:SolidPeso molecular:436.52Caroverine hydrochloride
CAS:Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Fórmula:C22H28ClN3O2Pureza:98.37% - 98.75%Cor e Forma:SolidPeso molecular:401.9VU 0364439
CAS:VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).Fórmula:C18H13Cl2N3O3SPureza:97.9%Cor e Forma:SolidPeso molecular:422.29
![1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT60224.webp&w=3840&q=75)
