GluR
Inibidores do Receptor de Glutamato são compostos que bloqueiam a atividade dos receptores de glutamato, os principais receptores de neurotransmissores excitatórios no cérebro. Esses receptores desempenham um papel crucial na transmissão sináptica, plasticidade, aprendizado e memória. A desregulação da sinalização do glutamato está associada a vários distúrbios neurológicos, como epilepsia, AVC e doenças neurodegenerativas. Os inibidores dos receptores de glutamato são essenciais para investigar os mecanismos de excitotoxicidade e desenvolver estratégias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de receptores de glutamato para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.
Foram encontrados 255 produtos de "GluR"
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(±)-LY367385
CAS:<p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>Fórmula:C10H11NO4Cor e Forma:SolidPeso molecular:209.201MPPG
CAS:<p>MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).</p>Fórmula:C9H12NO5PCor e Forma:SolidPeso molecular:245.171KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Fórmula:C22H12F3N5Na2O7Pureza:97.27%Cor e Forma:SoildPeso molecular:561.33LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Fórmula:C25H31F2NO11SCor e Forma:SolidPeso molecular:591.58(S,S)-BMS-984923
CAS:<p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.</p>Fórmula:C22H15ClN2O2Cor e Forma:SolidPeso molecular:374.82STX-107
CAS:<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Fórmula:C18H10FN3SPureza:99.17%Cor e Forma:SolidPeso molecular:319.36JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Cor e Forma:SolidLY2812223
CAS:<p>LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).</p>Fórmula:C10H12N4O4SPureza:98%Cor e Forma:SolidPeso molecular:284.29MGS0274
CAS:<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Fórmula:C21H32FNO7Cor e Forma:SolidPeso molecular:429.485ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Fórmula:C19H15FN2OPureza:99.98% - 99.98%Cor e Forma:SoildPeso molecular:306.331H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Fórmula:C10H12N2O2SPureza:99.96%Cor e Forma:SoildPeso molecular:224.28LY3020371
CAS:<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Fórmula:C15H15F2NO5SCor e Forma:SolidPeso molecular:359.34LY3027788 hydrochloride
CAS:<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Fórmula:C25H32ClF2NO11SCor e Forma:SolidPeso molecular:628.03(S)-3,4-DCPG
CAS:<p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>Fórmula:C10H9NO6Pureza:98%Cor e Forma:SolidPeso molecular:239.18MGS0028
CAS:<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Fórmula:C8H8FNO5Cor e Forma:SolidPeso molecular:217.15L-AP3
CAS:<p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>Fórmula:C3H8NO5PCor e Forma:White Hygroscopic SolidPeso molecular:169.073(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Fórmula:C10H10ClNO6Pureza:99.53% - 99.9%Cor e Forma:SoildPeso molecular:275.64NS-102
CAS:<p>NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.</p>Fórmula:C12H11N3O4Pureza:98.48% - 98.95%Cor e Forma:SolidPeso molecular:261.23VU0422288
CAS:<p>VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.</p>Fórmula:C17H11Cl2N3O2Pureza:95.48%Cor e Forma:SolidPeso molecular:360.19VU0364770 hydrochloride
CAS:VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).Fórmula:C12H10Cl2N2OPureza:98%Cor e Forma:SolidPeso molecular:269.13
![1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT60224.webp&w=3840&q=75)
