GluR
Inibidores do Receptor de Glutamato são compostos que bloqueiam a atividade dos receptores de glutamato, os principais receptores de neurotransmissores excitatórios no cérebro. Esses receptores desempenham um papel crucial na transmissão sináptica, plasticidade, aprendizado e memória. A desregulação da sinalização do glutamato está associada a vários distúrbios neurológicos, como epilepsia, AVC e doenças neurodegenerativas. Os inibidores dos receptores de glutamato são essenciais para investigar os mecanismos de excitotoxicidade e desenvolver estratégias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de receptores de glutamato para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.
Foram encontrados 263 produtos para "GluR".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
pep2-SVKI acetate
Pep2-SVKI acetate(pep2-SVKI acetate (328944-75-8 free base)) is a synthetic peptide salt that prevents internalization of AMPA-type glutamate receptor.Fórmula:C62H97N13O20Pureza:97.14%Cor e Forma:SolidPeso molecular:1344.51ADX-47273
CAS:ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).Fórmula:C20H17F2N3O2Pureza:97% - 99.22%Cor e Forma:White SolidPeso molecular:369.36AZD-8529
CAS:AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.Fórmula:C24H24F3N5O3Cor e Forma:SolidPeso molecular:487.47VU0361737
CAS:VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.Fórmula:C13H11ClN2O2Pureza:99.60% - 99.85%Cor e Forma:SolidPeso molecular:262.69CX614
CAS:CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.Fórmula:C13H13NO4Pureza:97.37%Cor e Forma:White SolidPeso molecular:247.25Ref: TM-T19698
5mg52,00€1mL*10mM (DMSO)55,00€10mg78,00€25mg119,00€50mg172,00€100mg259,00€200mg388,00€LY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFórmula:C19H22N2O2SPureza:99.34%Cor e Forma:White SolidPeso molecular:342.46Ref: TM-T7706
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg86,00€25mg156,00€50mg225,00€100mg321,00€200mg447,00€NBQX
CAS:NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.Fórmula:C12H8N4O6SPureza:97.66% - 99.93%Cor e Forma:SolidPeso molecular:336.28Ref: TM-T4113
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg114,00€25mg222,00€50mg334,00€100mg497,00€200mg717,00€trans-ACPD
CAS:trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.Fórmula:C7H11NO4Pureza:99.98%Cor e Forma:White SolidPeso molecular:173.17Ref: TM-T3484
1mg46,00€2mg59,00€1mL*10mM (DMSO)71,00€5mg94,00€10mg140,00€25mg264,00€50mg477,00€100mg692,00€MPEP
CAS:MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.Fórmula:C14H11NPureza:99.54%Cor e Forma:White SolidPeso molecular:193.24HBT1
CAS:HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neuronsFórmula:C16H17F3N4O2SPureza:99.52%Cor e Forma:White SolidPeso molecular:386.39VU0364770
CAS:VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGluFórmula:C12H9ClN2OPureza:99.65% - 99.96%Cor e Forma:White SolidPeso molecular:232.67TCN238
CAS:TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).Fórmula:C12H11N3Pureza:99.9% - 99.92%Cor e Forma:White SolidPeso molecular:197.24pep2-EVKI acetate(1315378-67-6 free base)
Pep2-EVKI acetate, a cell-permeable peptide, disrupts PICK1-GluR2 AMPA receptor binding.Fórmula:C64H99N13O21Pureza:99.85%Cor e Forma:SolidPeso molecular:1386.55Ro 67-7476
CAS:Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors.Fórmula:C17H18FNO2SPureza:99.69%Cor e Forma:SolidPeso molecular:319.39Lu AF21934
CAS:Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).Fórmula:C14H16Cl2N2O2Pureza:99.01%Cor e Forma:SolidPeso molecular:315.2IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Fórmula:C8H9ClN2O2SPureza:99.73%Cor e Forma:White SolidPeso molecular:232.69Ro0711401
CAS:Ro0711401 is an agonist of mGlu1 receptor.Fórmula:C18H11F3N2O3Pureza:97.57%Cor e Forma:SolidPeso molecular:360.29VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Fórmula:C17H17F2NO2Pureza:99% - 99.98%Cor e Forma:SolidPeso molecular:305.32YM90K
CAS:YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.Fórmula:C11H8ClN5O4Pureza:98.23%Cor e Forma:SolidPeso molecular:309.66Ref: TM-T8435
1mg73,00€5mg160,00€1mL*10mM (DMSO)170,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€FITM
CAS:FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).Fórmula:C18H18FN5OSPureza:97.25% - 99.23%Cor e Forma:White SolidPeso molecular:371.43Ref: TM-T7292
1mg34,00€2mg44,00€1mL*10mM (DMSO)62,00€5mg66,00€10mg92,00€25mg177,00€50mg268,00€100mg394,00€
