AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 632 produtos de "AChR"
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SSR 180
CAS:SSR 180 is a potent and subtype-selective α7 agonist with applications in the study of Alzheimer;s disease and schizophrenia.Fórmula:C14H17BrN2O2Pureza:98.82%Cor e Forma:SoildPeso molecular:325.20Ref: TM-T84293
1mg115,00€2mg169,00€5mg275,00€10mg394,00€25mg615,00€50mg848,00€100mg1.121,00€200mg1.510,00€Carbetapentane citrate
CAS:Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.Fórmula:C20H31NO3·C6H8O7Pureza:99.46%Cor e Forma:White To Off-White SolidPeso molecular:525.59Diphenidol hydrochloride
CAS:Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.Fórmula:C21H28ClNOPureza:99.15% - 99.33%Cor e Forma:Crystals Soluble In Methanol WaterPeso molecular:345.91Tazomeline
CAS:Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.Fórmula:C14H23N3S2Pureza:99.63%Cor e Forma:SolidPeso molecular:297.48Promethazine hydrochloride
CAS:Promethazine HCl: First-gen antihistamine, H1 and mACh blocker, affects 5-HT2A/C, D2, α1 receptors.Fórmula:C17H20N2S·HClPureza:99.85%Cor e Forma:Crystals In Water Has A Ph Of 3 5-5 0 (Ntp 1992)Peso molecular:320.88Zelminemab
CAS:Zelminemab (AMG-301) is a human monoclonal antibody designed to target and inhibit the PACAP type I (PAC1) receptor [1].Pureza:98.8% (SDS-PAGE); 97% (SEC-HPLC) - 98.8% (SDS-PAGE); 97% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.17 kDaAtropine methyl bromide
CAS:Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist.Fórmula:C18H26BrNO3Pureza:99.7%Cor e Forma:SolidPeso molecular:384.308Ref: TM-T14345
1mg35,00€5mg66,00€10mg100,00€25mg177,00€50mg261,00€100mg383,00€200mg557,00€1mL*10mM (DMSO)73,00€Orphenadrine Citrate
CAS:Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.Fórmula:C18H23NO·C6H8O7Pureza:99.58%Cor e Forma:White SolidPeso molecular:461.5Dipivefrin hydrochloride
CAS:Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.Fórmula:C19H27NO5·HClPureza:99.22% - 99.92%Cor e Forma:Less Gas With A Sweet Odor Colorless Gas With A Sweet OdorPeso molecular:387.9V-11-0711 HCl
V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.Fórmula:C27H36ClNO3Pureza:99.87%Cor e Forma:SolidPeso molecular:458.03Trospium chloride
CAS:Trospium chloride treats urinary incontinence without causing liver damage.Fórmula:C25H30ClNO3Pureza:99.84% - >99.99%Cor e Forma:White To Off-White PowderPeso molecular:427.964Solifenacin succinate
CAS:Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 muscarinic antagonist, which is used as a urologic agent.Fórmula:C23H26N2O2·C4H6O4Pureza:99.85% - 99.98%Cor e Forma:SolidPeso molecular:480.56Pyrantel pamoate
CAS:Pyrantel pamoate (Pyrantel embonate) is a depolarizing neuromuscular blocking agent.Fórmula:C34H30N2O6SPureza:99.71%Peso molecular:594.69Primidone
CAS:Primidone (NCI-C56360) is a potent anticonvulsant agent.Fórmula:C12H14N2O2Pureza:99.91%Cor e Forma:Crystals (Ntp 1992)Peso molecular:218.25Pancuronium dibromide
CAS:Pancuronium dibromide (Pavulon), a competitive AChR antagonist, acts as a skeletal muscle relaxant. Pancuronium dibromide blocks neuromuscular transmission.Fórmula:C35H60Br2N2O4Pureza:99.86%Cor e Forma:solidPeso molecular:732.67Temephos
CAS:Temephos is an organothiophosphate insecticide and cholinesterase inhibitor for treating water with disease-carrying insects.
Fórmula:C16H20O6P2S3Pureza:≥95%Cor e Forma:White Crystalline Solid Or LiquidPeso molecular:466.47Tiotropium bromide
CAS:Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).Fórmula:C19H22BrNO4S2Pureza:96.82% - 99.97%Cor e Forma:White SolidPeso molecular:472.42Meclofenoxate hydrochloride
CAS:Meclofenoxate HCl (Lucidril) boosts memory and cognition; it's a DIMETHYLAMINOETHANOL and p-chlorophenoxyacetic acid ester.Fórmula:C12H16ClNO3·HClPureza:97.05%Cor e Forma:White Crystal PowderPeso molecular:294.17PF-4348235 2HCl
PF-4348235 2HCl is an adrenergic agonist and muscarinic receptor antagonist, and is a bronchodilator.Fórmula:C36H51Cl3N4O7SPureza:99.85%Cor e Forma:SolidPeso molecular:790.24Fipexide
CAS:Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983.Fórmula:C20H21ClN2O4Pureza:97.6% - 99.95%Cor e Forma:SolidPeso molecular:388.84Oxybutynin
CAS:Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.Fórmula:C22H31NO3Pureza:97.81% - 99.57%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:357.49Vecuronium bromide
CAS:Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscleFórmula:C34H57BrN2O4Pureza:99.63% - 99.92%Cor e Forma:White PowderPeso molecular:637.73Tolterodine tartrate
CAS:Tolterodine tartrate (PNU-200583E) is a potent antagonist for muscarinic receptor. It show selectivity for the urinary bladder and salivary glands in vivo.Fórmula:C22H31NO·C4H6O6Pureza:99.95%Cor e Forma:White-To-Off-White Crystalline PowderPeso molecular:475.58Methacholine Chloride
CAS:Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of acetylcholine.
Fórmula:C8H18ClNO2Pureza:99.37% - 99.74%Cor e Forma:White Hygroscopic Crystals With Slight Odor Of Dead FishPeso molecular:195.69Pirenzepine dihydrochloride
CAS:Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion.Fórmula:C19H21N5O2·2HClPureza:99.48% - 99.62%Cor e Forma:White PowderPeso molecular:424.32Benztropine mesylate
CAS:Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON
Fórmula:C21H25NO·CH4SO3Pureza:98.41% - 99.96%Cor e Forma:White Crystalline Powder; Odourless Or Almost OdourlessPeso molecular:403.53Bethanechol chloride
CAS:Bethanechol chloride: muscarinic agonist, boosts smooth muscle tone, used post-abdominal surgery & for urinary retention; may cause hypotension & bronchospasm.Fórmula:C7H17N2O2·ClPureza:95% - 99.73%Cor e Forma:White CrystallinePeso molecular:196.68Ribavirin
CAS:Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.Fórmula:C8H12N4O5Pureza:99.09% - 99.83%Cor e Forma:Less Solid Colourless SolidPeso molecular:244.20Pyrantel tartrate
CAS:Pyrantel tartrate (Banminth) is broad spectrum anthelmintic for livestock.Fórmula:C15H20N2O6SPureza:99.96%Cor e Forma:White CrystalsPeso molecular:356.39Droperidol
CAS:Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.Fórmula:C22H22FN3O2Pureza:97.16% - 98%Cor e Forma:SolidPeso molecular:379.43Ipratropium bromide monohydrate
CAS:Ipratropium bromide, safer than atropine, treats bronchial disorders, rhinitis, and irregular heartbeat via inhalation.Fórmula:C20H32BrNO4Pureza:97.85%Cor e Forma:SolidPeso molecular:430.389-Cyclopentyladenine
CAS:9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signalingFórmula:C10H13N5Pureza:99.98%Cor e Forma:SolidPeso molecular:203.24Nefiracetam
CAS:Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.Fórmula:C14H18N2O2Pureza:97.37%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:246.3Gallamine triethiodide
CAS:Gallamine triethiodide (Benzkurin), a synthetic inhibiting drug, is nondepolarizing.Fórmula:C30H60I3N3O3Pureza:98.90%Cor e Forma:White Amorphous Powder SolidPeso molecular:891.53Valethamate bromide
CAS:Valethamate bromide (Resitan) is an anticholinergic agent that has antispasmodic effects and inhibits glandular secretion.Fórmula:C19H32BrNO2Pureza:>99.99%Cor e Forma:SolidPeso molecular:386.37Methscopolamine
CAS:Methscopolamine (Hyoscine methyl bromide) (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.Fórmula:C18H24BrNO4Pureza:99.12% - ≥98%Cor e Forma:SolidPeso molecular:398.29Cotinine
CAS:Cotinine (NIH-10498) is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.Fórmula:C10H12N2OPureza:98% - 99.89%Cor e Forma:Viscous Oil SolidPeso molecular:176.22Dibucaine
CAS:Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.Fórmula:C20H29N3O2Pureza:99.698% - 99.88%Cor e Forma:Colorless Or Almost Colorless Powder SolidPeso molecular:343.46Disopyramide
CAS:Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Fórmula:C21H29N3OPureza:99.62%Cor e Forma:SolidPeso molecular:339.47Clevidipine
CAS:Clevidipine (Clevidipine butyrate) is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for bloodFórmula:C21H23Cl2NO6Pureza:99.40%Cor e Forma:PowderPeso molecular:456.32Bambuterol hydrochloride
CAS:Bambuterol hydrochloride (KWD-2183 hydrochloride) , a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma.Fórmula:C18H30ClN3O5Pureza:99.53% - 99.61%Cor e Forma:White SolidPeso molecular:403.912',5'-Dideoxyadenosine
CAS:2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).Fórmula:C10H13N5O2Pureza:99.55%Cor e Forma:White SolidPeso molecular:235.24Ref: TM-T10066
1mg39,00€5mg84,00€10mg119,00€25mg210,00€50mg354,00€100mg562,00€500mg1.225,00€1mL*10mM (DMSO)92,00€Clidinium bromide
CAS:Clidinium bromide (Ro 2-3773), a synthetic anticholinergic, treats peptic ulcers and alleviates abdominal cramps and IBS symptoms.Fórmula:C22H26BrNO3Pureza:98.89% - 99.86%Cor e Forma:White Crystalline SolidPeso molecular:432.35Flavoxate hydrochloride
CAS:Flavoxate hydrochloride (DW61) , a muscarinic AChR antagonist, is used in the therapy of various urinary syndromes and as an antispasmodic.Fórmula:C24H26ClNO4Pureza:99.78%Cor e Forma:White SolidPeso molecular:427.92nAChR agonist 1
CAS:nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.
Fórmula:C20H18ClNO3S2Pureza:97.59%Cor e Forma:SolidPeso molecular:419.94Homatropine Methylbromide
CAS:Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.Fórmula:C17H24BrNO3Pureza:98.97%Cor e Forma:SolidPeso molecular:370.29Deschloroclozapine
CAS:Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist.Fórmula:C18H20N4Pureza:99.61% - 99.98%Cor e Forma:SolidPeso molecular:292.38Darifenacin hydrobromide
CAS:Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Fórmula:C28H31BrN2O2Pureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:505.45Propantheline bromide
CAS:Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscleFórmula:C23H30BrNO3Pureza:98% - ≥98%Peso molecular:448.4MK-7622
CAS:MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.
Fórmula:C25H25N3O2Pureza:99.77% - 99.8%Cor e Forma:SolidPeso molecular:399.48Procainamide hydrochloride
CAS:Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analogFórmula:C13H21N3O·HClPureza:99.83% - 99.97%Cor e Forma:White To Slightly Yellow PowderPeso molecular:271.79Hexamethonium Bromide
CAS:Hexamethonium Bromide blocks neural nicotinic AChR, poorly absorbed in the gut, doesn't pass the blood-brain barrier.Fórmula:C12H30Br2N2Pureza:99.76%Cor e Forma:White Crystalline Powder And AgglomeratesPeso molecular:362.19Nicardipine hydrochloride
CAS:Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.Fórmula:C26H30ClN3O6Pureza:99.58% - 99.89%Cor e Forma:Yellow SolidPeso molecular:515.99Diphenmanil methylsulfate
CAS:Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors.Fórmula:C20H24N·CH3O4SPureza:98% - 99.27%Cor e Forma:SolidPeso molecular:389.51MN58b
CAS:MN58b is a selective inhibitor of choline kinase α (CHKα).Fórmula:C32H40Br2N4Pureza:97.23%Cor e Forma:SolidPeso molecular:640.49Ref: TM-T12085
1mg279,00€5mg683,00€10mg888,00€25mg1.395,00€50mg1.783,00€100mg2.512,00€1mL*10mM (DMSO)862,00€Dequalinium chloride
CAS:Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.
Fórmula:C30H40Cl2N4Pureza:99.79% - 99.9%Cor e Forma:SolidPeso molecular:527.59(Rac)-ABT-202 dihydrochloride
CAS:(Rac)-ABT-202 dihydrochloride is a racemate of ABT-202. ABT-202 is an nicotinic acetylcholine receptors (nAChRs) agonist and can be used as an analgesic.Fórmula:C9H15Cl2N3Pureza:97.4%Cor e Forma:SolidPeso molecular:236.142Nebracetam hydrochloride
CAS:Nebracetam HCl (WEB 1881 FU) is an M1-muscarinic agonist nootropic, increasing intracellular Ca2+ with an EC50 of 1.59 mM.Fórmula:C12H17ClN2OPureza:99.23%Cor e Forma:SolidPeso molecular:240.729(Rac)-Sabcomeline HCl
CAS:Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.Fórmula:C10H16ClN3OPureza:99.58%Cor e Forma:SoildPeso molecular:229.71DL-trihexyphenidyl hydrochloride
CAS:DL-trihexyphenidyl hydrochloride (Trihexyphenidyl HCl) is a muscarinic antagonist.Fórmula:C20H32ClNOPureza:99.63% - 99.71%Cor e Forma:SolidPeso molecular:337.93Carbachol
CAS:Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.Fórmula:C6H15ClN2O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:182.65TAK-071
CAS:TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).
Fórmula:C24H24FN3O3Pureza:98.02%Cor e Forma:SolidPeso molecular:421.46Acetamiprid
CAS:Acetamiprid: nAChR agonist, global neonicotinoid insecticide linked to neuromuscular/reproductive issues.Fórmula:C10H11ClN4Pureza:99.66%Cor e Forma:White PowderPeso molecular:222.67Adiphenine hydrochloride
CAS:Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.Fórmula:C20H25NO2·HClPureza:97.76% - 99.53%Cor e Forma:White Or Almost White PowderPeso molecular:347.88Rocuronium bromide
CAS:Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker, which is used to provide skeletal muscle relaxation.Fórmula:C32H53BrN2O4Pureza:99.77% - >99.99%Cor e Forma:White Or Off-White PowderPeso molecular:609.68Benzethonium chloride
CAS:Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.Fórmula:C27H42ClNO2Pureza:99.91%Cor e Forma:White To Off-White Solid Solid Particulate/PowderPeso molecular:448.09Dicyclomine hydrochloride
CAS:Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.Fórmula:C19H36ClNO2Pureza:99.81%Cor e Forma:SolidPeso molecular:345.95Lysipressin acetate(50-57-7(fb_acetate))
CAS:Lysipressin acetate (50-57-7), triggers rabbit bladder contraction & activates adenylate cyclase, is an antidiuretic in pigs & marsupials.
Fórmula:C48H69N13O14S2Pureza:98.08%Cor e Forma:SolidPeso molecular:1116.28VU 0365114
CAS:VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).Fórmula:C22H14F3NO3Pureza:99.86%Cor e Forma:SolidPeso molecular:397.35Ref: TM-T13325
2mg38,00€5mg58,00€10mg82,00€25mg137,00€50mg224,00€100mg335,00€200mg469,00€1mL*10mM (DMSO)65,00€Fesoterodine fumarate
CAS:Fesoterodine fumarate (Toviaz) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.Fórmula:C26H37NO3·C4H4O4Pureza:99.16%Cor e Forma:White SolidPeso molecular:527.65Ref: TM-T1475
2mg35,00€5mg49,00€10mg74,00€25mg105,00€50mg144,00€100mg215,00€500mg419,00€1mL*10mM (DMSO)57,00€Lupanine hydrochloride
CAS:Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.Fórmula:C15H25ClN2OCor e Forma:SolidPeso molecular:284.83β2AR/M-receptor agonist-1
CAS:β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor andFórmula:C43H56BrN3O7Cor e Forma:SolidPeso molecular:806.82nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.66nAChR modulator-2
CAS:nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.66Perindoprilat
CAS:Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.Fórmula:C17H28N2O5Pureza:99.21%Cor e Forma:SolidPeso molecular:340.41Navafenterol saccharinate
CAS:AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).Fórmula:C45H47N7O9S3Cor e Forma:SolidPeso molecular:926.09Irsogladine maleate
CAS:Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C9H7Cl2N5Cor e Forma:SolidPeso molecular:256.09Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Fórmula:C10H14N2OCor e Forma:SolidPeso molecular:178.23Methylatropine (nitrate)
CAS:Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.Fórmula:C18H26N2O6Cor e Forma:SolidPeso molecular:366.414Atracurium
CAS:Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.Fórmula:C53H72N2O122Cor e Forma:SolidPeso molecular:929.14(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.
Fórmula:C22H32ClNO2Cor e Forma:SolidPeso molecular:377.95(R)-Dinotefuran
CAS:(R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.Fórmula:C7H14N4O3Cor e Forma:SolidPeso molecular:202.21DSPE-PEG1000-RVG29
DSPE-PEG1000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 can specifically bind to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and cross the BBB.Cor e Forma:Odour SolidMuscarine
CAS:Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Fórmula:C9H20NO2Pureza:98%Cor e Forma:SolidPeso molecular:174.26(rel)-Asperparaline A
CAS:Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.
Fórmula:C20H29N3O3Cor e Forma:SolidPeso molecular:359.47Lobeline sulfate
CAS:Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.Fórmula:C22H29NO6SPureza:98%Cor e Forma:White PowderPeso molecular:435.54MK-0969
CAS:MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.Fórmula:C24H30F2N4O2Cor e Forma:SolidPeso molecular:444.52TMPH
CAS:TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.Fórmula:C16H31NO2Pureza:99.78%Cor e Forma:SoildPeso molecular:269.42Ref: TM-T60080
2mg38,00€5mg58,00€10mg88,00€25mg140,00€50mg215,00€100mg319,00€200mg449,00€1mL*10mM (DMSO)57,00€8-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Fórmula:C5H6N6Pureza:99.82%Cor e Forma:SolidPeso molecular:150.14TC-2559 difumarate
CAS:TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.Fórmula:C20H26N2O9Cor e Forma:SolidPeso molecular:438.43M3/PDE4 modulator-1
M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.Fórmula:C38H41Cl2N3O8SCor e Forma:SolidPeso molecular:770.72Octamylamine
CAS:Octamylamine is a bioactive chemical.Fórmula:C13H29NCor e Forma:SolidPeso molecular:199.3761nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Fórmula:C18H20Cl2N4OCor e Forma:SolidPeso molecular:379.29Dicloromezotiaz
CAS:Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.Fórmula:C19H12Cl3N3O2SCor e Forma:SolidPeso molecular:452.74(R)-(+)-Anatabine
CAS:(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.Fórmula:C10H12N2Pureza:98%Cor e Forma:SolidPeso molecular:160.22Heliosupine N-oxide
Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.Fórmula:C20H31NO8Cor e Forma:SolidPeso molecular:413.467rac-Desethyl Oxybutynin (hydrochloride)
CAS:rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.Fórmula:C20H28ClNO3Cor e Forma:SolidPeso molecular:365.89α-Bungarotoxin
CAS:Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).Fórmula:C338H529N97O105S11Pureza:98%Cor e Forma:SolidPeso molecular:7984.14AC1-IN-1
CAS:AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).
Fórmula:C18H18FN5O2Pureza:99.89%Cor e Forma:SolidPeso molecular:355.37Doxacurium Chloride
CAS:Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.Fórmula:C56H78ClN2O16Pureza:98%Cor e Forma:SolidPeso molecular:1070.69
