AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 636 produtos de "AChR"
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Heliosupine N-oxide
Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.Fórmula:C20H31NO8Cor e Forma:SolidPeso molecular:413.467(R)-(+)-Anatabine
CAS:(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.Fórmula:C10H12N2Pureza:98%Cor e Forma:SolidPeso molecular:160.22Angiopeptin
CAS:Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.Fórmula:C54H71N11O10S2Cor e Forma:SolidPeso molecular:1098.34nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Fórmula:C18H20Cl2N4OCor e Forma:SolidPeso molecular:379.29Metixene
CAS:Metixene is an anticholinergic drug. It was developed as a treatment against Parkinson's disease.Fórmula:C20H23NSCor e Forma:LiquidPeso molecular:309.47PDE4-IN-4
CAS:PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment ofFórmula:C36H37Cl2N3O7SCor e Forma:SolidPeso molecular:726.675-AAM-2-CP
CAS:5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.Fórmula:C8H9ClN2OPureza:99.58%Cor e Forma:SolidPeso molecular:184.62TC-2216
CAS:TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.Fórmula:C12H17N3Pureza:99.81%Cor e Forma:SolidPeso molecular:203.28(S)-UFR2709 hydrochloride
CAS:(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.Fórmula:C13H18ClNO2Pureza:98.94%Cor e Forma:SolidPeso molecular:255.74Tiquizium
CAS:Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.
Fórmula:C19H24NS2Pureza:99.82%Cor e Forma:SolidPeso molecular:330.53α-Conotoxin PIA TFA
α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.Fórmula:C81H126F3N27O27S4Pureza:98.81%Cor e Forma:SolidPeso molecular:2095.3α-Muricholic acid
CAS:α-Muricholic acid is the most abundant primary bile acid in rodents.Fórmula:C24H40O5Pureza:98%Cor e Forma:SolidPeso molecular:408.57[Ala2,8,9,11,19,22,24,25,27,28]-VIP
CAS:[Ala2,8,9,11,19,22,24,25,27,28]-VIP can be used for related research in the field of life sciences. Its product number is T36637 and CAS number is 866552-34-3.Fórmula:C131H219N41O33SCor e Forma:SolidPeso molecular:2928.51R-(+)-Cotinine
CAS:R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.Fórmula:C10H12N2OCor e Forma:SolidPeso molecular:176.223-hydroxy Darifenacin
CAS:3-hydroxy Darifenacin, darifenacin metabolite, blocks M1-5 muscarinic receptors with varying potency (Kis: 2.24-79.43 nM) in CHO cells.Fórmula:C28H30N2O3Cor e Forma:SolidPeso molecular:442.559LtIA-F
LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.Fórmula:C86H121N25O22S4Cor e Forma:SolidPeso molecular:1985.31(S)-Dinotefuran
CAS:(S)-Dinotefuran, a neonicotinoid, more toxic to bees than its R-isomer, targets α8 nAChR.Fórmula:C7H14N4O3Cor e Forma:SolidPeso molecular:202.21Imidafenacin Metabolite M4
CAS:Imidafenacin M4 is a CYP3A4-formed metabolite of the muscarinic antagonist imidafenacin.Fórmula:C18H19N3O3Cor e Forma:SolidPeso molecular:325.368ANQ-9040
CAS:ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.Fórmula:C36H58N2O5SCor e Forma:SolidPeso molecular:630.92Octamylamine
CAS:Octamylamine is a bioactive chemical.Fórmula:C13H29NCor e Forma:SolidPeso molecular:199.3761Epiboxidine hydrochloride
CAS:Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.Fórmula:C10H15ClN2OCor e Forma:SolidPeso molecular:214.69M1/M4 muscarinic agonist 2
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].Cor e Forma:Odour SolidFlupyradifurone
CAS:Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.Fórmula:C12H11ClF2N2O2Pureza:99.83%Cor e Forma:SolidPeso molecular:288.68Navafenterol
CAS:AZD-8871, a potential COPD and asthma treatment, may work well with ICS.Fórmula:C38H42N6O6S2Cor e Forma:SolidPeso molecular:742.91sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Fórmula:C10H15N3OCor e Forma:SolidPeso molecular:193.25Atracurium
CAS:Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.Fórmula:C53H72N2O122Cor e Forma:SolidPeso molecular:929.14Lupanine hydrochloride
CAS:Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.Fórmula:C15H25ClN2OCor e Forma:SolidPeso molecular:284.83Small Cardioactive Peptide B (SCPB)
CAS:SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).Fórmula:C52H80N14O11S2Pureza:98%Cor e Forma:SolidPeso molecular:1141.41Methylatropine (nitrate)
CAS:Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.Fórmula:C18H26N2O6Cor e Forma:SolidPeso molecular:366.414CDD0102 HCl
CAS:CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.Fórmula:C8H13ClN4OPureza:99.7%Cor e Forma:SoildPeso molecular:216.67Destomycin A
CAS:Destomycin A, an aminoglycoside antibiotic, exhibits activity against bacterial (Gram-positive and Gram-negative), antifungal, and anthelmintic agents. It inhibits peptide synthesis in Escherichia coli cells and stimulates adenylate cyclase in animal tissues.Fórmula:C20H37N3O13Cor e Forma:SolidPeso molecular:527.52(+)-Coclaurine hydrochloride
CAS:(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.Fórmula:C17H20ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:321.8Fentonium bromide
CAS:Fentonium bromide is a biochemical.Fórmula:C31H34BrNO4Cor e Forma:SolidPeso molecular:564.51nAChR modulator-2
CAS:nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.66α-Conotoxin PIA
CAS:Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nMFórmula:C79H125N27O25S4Pureza:98%Cor e Forma:SolidPeso molecular:1981.3Ebiratide
CAS:Ebiratide is an analog of ACTH 4-9.Fórmula:C48H73N11O10SPureza:98%Cor e Forma:SolidPeso molecular:996.23[D-Trp7,9,10]-Substance P
CAS:Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
Fórmula:C79H105N21O13SPureza:98%Cor e Forma:SolidPeso molecular:1588.89Pozanicline hydrochloride
Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.Fórmula:C11H17ClN2OPureza:97.13% - 99.81%Cor e Forma:SolidPeso molecular:228.72Ref: TM-T16563L
1mg77,00€5mg155,00€10mg220,00€25mg338,00€50mg472,00€100mg632,00€200mg853,00€1mL*10mM (DMSO)134,00€Desfesoterodine
CAS:Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.Fórmula:C22H31NO2Pureza:99.77%Cor e Forma:SolidPeso molecular:341.49Ref: TM-T6364
1mg63,00€5mg137,00€10mg205,00€25mg353,00€50mg520,00€100mg750,00€500mg1.521,00€1mL*10mM (DMSO)150,00€Oxotremorine
CAS:Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.Fórmula:C12H18N2OCor e Forma:SolidPeso molecular:206.28PF-06827443
PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.Fórmula:C24H24N2O4Cor e Forma:SolidPeso molecular:404.47N,N-Dicyclohexylcarbodiimide
CAS:N,N-Dicyclohexylcarbodiimide (Dicyclohexylcarbodiimide) is a cross-linking agent used in the synthesis of active ester-containing reagents.Fórmula:C13H22N2Pureza:98.28% - 99.73%Cor e Forma:SolidPeso molecular:206.335-Hydroxymethyl tolterodine formate
CAS:5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.Fórmula:C23H33NO4Cor e Forma:SolidPeso molecular:387.515-AMAM-2-CP
CAS:5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].Fórmula:C9H11ClN2OCor e Forma:SolidPeso molecular:198.65(Rac)-5-Carboxy tolterodine
CAS:(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.Fórmula:C22H29NO3Cor e Forma:SolidPeso molecular:355.47Thiothixene
CAS:Thiothixene has a wide range of applications in life science related research.Fórmula:C23H29N3O2S2Cor e Forma:SolidPeso molecular:443.62bPiDDB
CAS:bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Fórmula:C24H38Br2N2Pureza:98.72%Cor e Forma:SolidPeso molecular:514.38RuBi-Nicotine
CAS:Nicotinic receptor agonistFórmula:C40H44Cl2N8RuPureza:98%Cor e Forma:SolidPeso molecular:808.81M4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Fórmula:C14H18N4OSPureza:99.14%Cor e Forma:SolidPeso molecular:290.38(R)-Dinotefuran
CAS:(R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.Fórmula:C7H14N4O3Cor e Forma:SolidPeso molecular:202.21NNC 11-1607
CAS:NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.Fórmula:C30H32N6O2S2Cor e Forma:SolidPeso molecular:572.74Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Fórmula:C10H14N2OCor e Forma:SolidPeso molecular:178.23Navafenterol saccharinate
CAS:AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).Fórmula:C45H47N7O9S3Cor e Forma:SolidPeso molecular:926.09α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFórmula:C83H125N27O27S5Pureza:98%Cor e Forma:SolidPeso molecular:2093.37DSPE-PEG5000-RVG29
DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.Cor e Forma:Odour SolidTC-2559 difumarate
CAS:TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.Fórmula:C20H26N2O9Cor e Forma:SolidPeso molecular:438.43Lobeline sulfate
CAS:Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.Fórmula:C22H29NO6SPureza:98%Cor e Forma:White PowderPeso molecular:435.54Mant-GTPγS
CAS:Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.Fórmula:C18H23N6O14P3SCor e Forma:SolidPeso molecular:672.39Hydroxybupropion
CAS:Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).Fórmula:C13H18ClNO2Pureza:99.73%Cor e Forma:Off-White SolidPeso molecular:255.74Ref: TM-T11588
1mg89,00€5mg204,00€10mg331,00€25mg545,00€50mg777,00€100mg1.063,00€1mL*10mM (DMSO)232,00€Irsogladine maleate
CAS:Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C9H7Cl2N5Cor e Forma:SolidPeso molecular:256.09(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.
Fórmula:C22H32ClNO2Cor e Forma:SolidPeso molecular:377.95Bensultap
CAS:Bensultap is an agricultural chemical typically used as a pesticide.Fórmula:C17H21NO4S4Pureza:98%Cor e Forma:SolidPeso molecular:431.61Aceclidine (hydrochloride)
CAS:agonist of muscarinic receptorsFórmula:C9H16ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:205.68Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Fórmula:C10H12N2Cor e Forma:SolidPeso molecular:160.22Ebiratide TFA
Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.Fórmula:C48H73N11O10S·xC2HF3O2Cor e Forma:SolidPeso molecular:996.23 (free base)Perindoprilat
CAS:Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.Fórmula:C17H28N2O5Pureza:99.21%Cor e Forma:SolidPeso molecular:340.41trans-Cevimeline hydrochloride
CAS:AF 102A hydrochloride is a biochemical.Fórmula:C10H18ClNOSCor e Forma:SolidPeso molecular:235.77Lu AE51090
CAS:Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.Fórmula:C24H29N3O3Pureza:99.57%Cor e Forma:SolidPeso molecular:407.51G-Protein antagonist peptide
CAS:Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.Fórmula:C57H64N12O9SPureza:98%Cor e Forma:SolidPeso molecular:1093.27nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.66Soclenicant
CAS:Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFórmula:C24H26N4O3Pureza:99.57%Cor e Forma:SoildPeso molecular:418.49Muscarine
CAS:Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Fórmula:C9H20NO2Pureza:98%Cor e Forma:SolidPeso molecular:174.26β2AR/M-receptor agonist-1
CAS:β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor andFórmula:C43H56BrN3O7Cor e Forma:SolidPeso molecular:806.82(±)-Coniine
CAS:(±)-Coniine, a piperidine alkaloid, is a toxin found in poison hemlock.Fórmula:C8H17NCor e Forma:SolidPeso molecular:127.23N-Ethyl-N-(3-pyridylmethyl)amine
CAS:N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.Fórmula:C8H12N2Pureza:99.65%Cor e Forma:SolidPeso molecular:136.19LAS190792
CAS:LAS190792 (AZD8999) is a dual muscarinic antagonist/β2-agonist, pIC50s (M1-M5, β1-β3): 8.9-5.6; used as a bronchodilator.Fórmula:C39H43ClN4O9S2Cor e Forma:SolidPeso molecular:811.36TIP 39, Tuberoinfundibular Neuropeptide
CAS:TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.Fórmula:C202H325N61O54SPureza:98%Cor e Forma:SolidPeso molecular:4504.2Biperiden Hydrochloride
CAS:Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.Fórmula:C21H30ClNOPureza:98%Cor e Forma:SolidPeso molecular:347.92nAChR agonist 2
CAS:Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,Fórmula:C11H16N2Cor e Forma:SolidPeso molecular:176.263TDI-10229
CAS:TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.Fórmula:C16H16ClN5Pureza:99.85% - 99.89%Cor e Forma:SoildPeso molecular:313.78Ref: TM-T64355
1mg39,00€5mg157,00€10mg224,00€25mg409,00€50mg615,00€100mg888,00€200mg1.198,00€1mL*10mM (DMSO)167,00€Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Fórmula:C20H21F3N4OPureza:99.96%Cor e Forma:SolidPeso molecular:390.4Ref: TM-T9694
1mg127,00€2mgA consultar5mg305,00€10mg494,00€25mg882,00€50mg1.198,00€100mg1.586,00€1mL*10mM (DMSO)338,00€BTMPS
CAS:BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.Fórmula:C28H52N2O4Pureza:98.1%Cor e Forma:SolidPeso molecular:480.72M3/PDE4 modulator-1
M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.Fórmula:C38H41Cl2N3O8SCor e Forma:SolidPeso molecular:770.72Migrastatin
CAS:Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinicFórmula:C27H39NO7Cor e Forma:SolidPeso molecular:489.609Bencycloquidium Bromide
CAS:Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.Fórmula:C21H32BrNO2Cor e Forma:SolidPeso molecular:410.39DSPE-PEG2000-RVG29
DSPE-PEG2000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and can traverse the BBB.Cor e Forma:Odour SolidBis-Br-ANT-ATP tetrasodium
Bis-Br-ANT-ATP(tetrasodium) is a fluorescent derivative of adenosine-5'-triphosphate (ATP). It selectively inhibits the adenylyl cyclase toxin CyaA of Bordetella pertussis with a Ki of 12.6 nM. This compound is utilized in research related to whooping cough.Cor e Forma:Odour SolidDoxacurium Chloride
CAS:Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.Fórmula:C56H78ClN2O16Pureza:98%Cor e Forma:SolidPeso molecular:1070.69VU6028418
CAS:VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).Cor e Forma:Solid(rel)-Asperparaline A
CAS:Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.
Fórmula:C20H29N3O3Cor e Forma:SolidPeso molecular:359.47Guanylyl Imidodiphosphate (lithium salt)
CAS:Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.Fórmula:C10H13Li4N6O13P3Cor e Forma:SolidPeso molecular:545.93Br-PBTC
CAS:Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.Fórmula:C14H15BrN2OSCor e Forma:SolidPeso molecular:339.25Rivanicline 2HCl
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.Fórmula:C10H16Cl2N2Pureza:99.4%Cor e Forma:SoildPeso molecular:235.15Ref: TM-T12738L1
1mg35,00€5mg74,00€10mg105,00€25mg246,00€50mg444,00€100mg650,00€1mL*10mM (DMSO)116,00€Proadrenomedullin (1-20), human
CAS:Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.Fórmula:C112H178N36O27Pureza:98%Cor e Forma:SolidPeso molecular:2460.84Albanin A
Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.Fórmula:C20H18O6Cor e Forma:SolidPeso molecular:354.358α-Bungarotoxin
CAS:Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).Fórmula:C338H529N97O105S11Pureza:98%Cor e Forma:SolidPeso molecular:7984.14Rocuronium
CAS:Rocuronium is an blocker of aminosteroid non-depolarizing neuromuscular.Fórmula:C32H53N2O4Pureza:98%Cor e Forma:SolidPeso molecular:529.77(-)-Coclaurine hydrochloride
CAS:(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.Fórmula:C17H20ClNO3Pureza:99.07%Cor e Forma:SoildPeso molecular:321.8Ref: TM-TN1519L
1mg115,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)249,00€ABT-107
CAS:ABT-107: α7 neuronal receptor agonist; protects rats' brains from 6-OHDA-induced damage.Fórmula:C19H20N4OCor e Forma:SolidPeso molecular:320.396
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