AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 575 produtos de "AChR"
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Perlapine
CAS:<p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>Fórmula:C19H21N3Cor e Forma:SolidPeso molecular:291.39Octamylamine
CAS:<p>Octamylamine is a bioactive chemical.</p>Fórmula:C13H29NCor e Forma:SolidPeso molecular:199.3761Destomycin A
CAS:<p>Destomycin A, an aminoglycoside antibiotic, exhibits activity against bacterial (Gram-positive and Gram-negative), antifungal, and anthelmintic agents. It inhibits peptide synthesis in Escherichia coli cells and stimulates adenylate cyclase in animal tissues.</p>Fórmula:C20H37N3O13Cor e Forma:SolidPeso molecular:527.52G-Protein antagonist peptide
CAS:<p>Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.</p>Fórmula:C57H64N12O9SPureza:98%Cor e Forma:SolidPeso molecular:1093.27Irsogladine maleate
CAS:<p>Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H7Cl2N5Cor e Forma:SolidPeso molecular:256.09M 8218
CAS:<p>M 8218 is a bioactive chemical.</p>Fórmula:C20H29NO2Cor e Forma:SolidPeso molecular:315.45nAChR modulator-2
CAS:<p>nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.66nAChR agonist 2
CAS:<p>Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,</p>Fórmula:C11H16N2Cor e Forma:SolidPeso molecular:176.263Fentonium bromide
CAS:<p>Fentonium bromide is a biochemical.</p>Fórmula:C31H34BrNO4Cor e Forma:SolidPeso molecular:564.51bPiDDB
CAS:<p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>Fórmula:C24H38Br2N2Pureza:98.72%Cor e Forma:SolidPeso molecular:514.38Guanylyl Imidodiphosphate (lithium salt)
CAS:<p>Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.</p>Fórmula:C10H13Li4N6O13P3Cor e Forma:SolidPeso molecular:545.93VU6028418
CAS:<p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>Cor e Forma:Solid5-AMAM-2-CP
CAS:<p>5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].</p>Fórmula:C9H11ClN2OCor e Forma:SolidPeso molecular:198.65R-(+)-Cotinine
CAS:<p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>Fórmula:C10H12N2OCor e Forma:SolidPeso molecular:176.22PDE4-IN-4
CAS:<p>PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment of</p>Fórmula:C36H37Cl2N3O7SCor e Forma:SolidPeso molecular:726.67DSPE-PEG5000-RVG29
<p>DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.</p>Cor e Forma:Odour SolidnAChR modulator-1
CAS:<p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Fórmula:C12H8ClN3O2Cor e Forma:SolidPeso molecular:261.66PF-06827443
<p>PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.</p>Fórmula:C24H24N2O4Cor e Forma:SolidPeso molecular:404.47Soclenicant
CAS:<p>Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availability</p>Fórmula:C24H26N4O3Pureza:99.57%Cor e Forma:SoildPeso molecular:418.49Bencycloquidium Bromide
CAS:<p>Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.</p>Fórmula:C21H32BrNO2Cor e Forma:SolidPeso molecular:410.39
