AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 575 produtos de "AChR"
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SCH 57790
CAS:<p>SCH 57790: selective muscarinic M2 blocker, boosts acetylcholine & cognition, may treat Alzheimer's.</p>Fórmula:C25H31N3O2SPureza:99% - 99.12%Cor e Forma:SolidPeso molecular:437.6TC-T 6000
CAS:<p>TC-T 6000 (hENT4-IN-1) is an ENT4 inhibitor with vasodilator activity that inhibits hENT1 and hENT2 for the study of cancer and cardiovascular damage.</p>Fórmula:C26H48N8O2Pureza:98.14%Cor e Forma:SolidPeso molecular:504.71Tarafenacin D-tartrate
CAS:<p>Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.</p>Fórmula:C25H26F4N2O8Pureza:99.86%Cor e Forma:SolidPeso molecular:558.48SIB-1553A hydrochloride
CAS:<p>SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand</p>Fórmula:C13H20ClNOSPureza:99.56% - 99.73%Cor e Forma:SolidPeso molecular:273.82JNJ-39393406
CAS:<p>JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.</p>Fórmula:C19H18F2N6O3Pureza:98.5%Cor e Forma:SolidPeso molecular:416.38PHA 543613
CAS:<p>PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.</p>Fórmula:C15H17N3O2Pureza:99.43% - 99.96%Cor e Forma:SolidPeso molecular:271.31Thonzylamine hydrochloride
CAS:<p>Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.</p>Fórmula:C16H23ClN4OPureza:99.67%Cor e Forma:White Crystalline PowderPeso molecular:322.83Desformylflustrabromine hydrochloride
CAS:<p>Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.</p>Fórmula:C17H12INO5Pureza:98.12%Cor e Forma:SolidPeso molecular:437.19AQW051
CAS:<p>AQW051 (VQW-765) is an oral α7-nAChR activator for cognitive impairments, used in anxiety disorder studies.</p>Fórmula:C19H22N2OPureza:99.94%Cor e Forma:SolidPeso molecular:294.39PF-03635659
CAS:<p>PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.</p>Fórmula:C28H32N2O3Pureza:98.39% - 99.83%Cor e Forma:SolidPeso molecular:444.57rel-(1R,2R)-Vesamicol Hydrochloride
CAS:<p>Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.</p>Fórmula:C17H26ClNOPureza:99.88%Cor e Forma:SolidPeso molecular:295.85SCH-900271
CAS:<p>SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.</p>Fórmula:C14H16N2O4Pureza:98.82% - 99.93%Cor e Forma:SolidPeso molecular:276.29CP-810123
CAS:<p>CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.</p>Fórmula:C14H18N4OPureza:98.63% - 99.60%Cor e Forma:SolidPeso molecular:258.32McN-A 343
CAS:<p>McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.</p>Fórmula:C14H18Cl2N2O2Pureza:99.65%Cor e Forma:SolidPeso molecular:317.21Tribendimidine
CAS:<p>Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.</p>Fórmula:C28H32N6Pureza:≥98%Cor e Forma:SolidPeso molecular:452.59Xanomeline
CAS:<p>Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.</p>Fórmula:C14H23N3OSPureza:99.61%Cor e Forma:SolidPeso molecular:281.42Dimethindene
CAS:<p>Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.</p>Fórmula:C20H24N2Pureza:98.3% - 98.99%Cor e Forma:SolidPeso molecular:292.42ASM-024
CAS:<p>ASM-024, a synthetic piperazine, activates nicotinic and β2-adrenergic receptors for potential asthma and bronchitis treatment with anti-inflammatory effects.</p>Fórmula:C15H25N2Pureza:99.74%Cor e Forma:SolidPeso molecular:233.37Otenzepad
CAS:<p>Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.</p>Fórmula:C24H31N5O2Pureza:99.79%Cor e Forma:SolidPeso molecular:421.54NB001
CAS:<p>NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.</p>Fórmula:C12H20N6OPureza:99.69%Cor e Forma:Off-White To Pale Pink SolidPeso molecular:264.33
