Protease serina
Os inibidores de serina protease são compostos que inibem as serina proteases, um grupo de enzimas caracterizado por um resíduo de serina no seu sítio ativo. Essas proteases estão envolvidas em vários processos fisiológicos, incluindo digestão, resposta imunológica, coagulação sanguínea e inflamação. Os inibidores de serina protease são importantes para o estudo de doenças onde essas enzimas estão desreguladas, como doenças cardiovasculares, câncer e condições inflamatórias. Na CymitQuimica, oferecemos inibidores de serina protease para apoiar sua pesquisa em enzimologia, mecanismos de doenças e intervenções terapêuticas.
Foram encontrados 70 produtos para "Protease serina".
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Alvelestat
CAS:Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.Fórmula:C25H22F3N5O4SPureza:98% - >99.99%Cor e Forma:White SolidPeso molecular:545.53Ref: TM-T3107
1mg34,00€2mg43,00€5mg56,00€1mL*10mM (DMSO)74,00€10mg84,00€25mg148,00€50mg219,00€100mg349,00€500mg830,00€KKI-5 acetate(97145-43-2 free base)
KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.Fórmula:C37H59N11O11Pureza:99.74%Cor e Forma:White SolidPeso molecular:833.95Benzamidine hydrochloride
CAS:Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.Fórmula:C7H9ClN2Pureza:99.64% - 99.97%Cor e Forma:SolidPeso molecular:156.612-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one
CAS:2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.Fórmula:C14H7BrClNO2Pureza:97.36%Cor e Forma:SolidPeso molecular:336.57ML281
CAS:ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.Fórmula:C22H19N3O2SPureza:99.12% - 99.87%Cor e Forma:SolidPeso molecular:389.47Ref: TM-T3423
1mg34,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg92,00€25mg178,00€50mg295,00€100mg474,00€500mg1.035,00€2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
CAS:2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urineFórmula:C13H16O3Pureza:99.53% - 99.81%Cor e Forma:SolidPeso molecular:220.26Ref: TM-T8802
1mg82,00€1mL*10mM (DMSO)146,00€5mg168,00€10mg244,00€25mg404,00€50mg567,00€100mg767,00€500mg1.521,00€Cetraxate hydrochloride
CAS:Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.Fórmula:C17H24ClNO4Pureza:99.75%Cor e Forma:SolidPeso molecular:341.83Galegenimab
CAS:Galegenimab (RG 6147) is an Fab targeting HtrA1, capable of blocking proteolytic cleavage of biglycan (an HtrA1 substrate), suitable for AMD research.Pureza:95% - 95.8% (SDS-PAGE); 99.7% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:46.87 kDaLanadelumab
CAS:Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.Pureza:95% - 97.4% (SDS-PAGE); 99.2% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.70 kDaAnti-Matriptase Antibody
Anti-Matriptase Antibody is a human antibody expressed in CHO cells.Pureza:95.8% (SDS-PAGE); 99.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.2% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:144.27 kDaMEGA-9
CAS:MEGA-9 (Nonanoyl-N-Methylglucamide) solubilizes membrane protein and can be used as a nonionic detergent.Fórmula:C16H33NO6Pureza:99.9%Cor e Forma:White SolidPeso molecular:335.44BMS-363131
CAS:BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.Fórmula:C28H40N6O5Pureza:97.99%Cor e Forma:SolidPeso molecular:540.65APC 366
CAS:APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Fórmula:C22H28N6O4Pureza:99.8%Cor e Forma:Yellow SolidPeso molecular:440.5WNK-IN-11-D3
CAS:WNK-IN-12 is an effective, selective, and orally active WNK1 kinase inhibitor.Fórmula:C21H18Cl2D3N5OSCor e Forma:SolidPeso molecular:465.42ZD-0892
CAS:ZD-0892: potent, selective neutrophil elastase inhibitor; Ki 6.7 nM (human), 200 nM (porcine).Fórmula:C24H32F3N3O5Pureza:95% - 99.53%Cor e Forma:SolidPeso molecular:499.52ZD8321
CAS:ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).Fórmula:C18H28F3N3O5Pureza:98%Cor e Forma:SolidPeso molecular:423.43AGLME
CAS:AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.Fórmula:C11H21N3O4Cor e Forma:SolidPeso molecular:259.3ZM223 hydrochloride (2031177-48-5 free base)
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.Fórmula:C23H18ClF3N4O2S2Pureza:98%Cor e Forma:SolidPeso molecular:538.99IPR-803
CAS:IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.Fórmula:C27H23N3O4Pureza:95% - 98%Cor e Forma:Red SolidPeso molecular:453.49WNK1-IN-1
CAS:WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Fórmula:C13H15BrCl2N2O4SPureza:98.09%Cor e Forma:SolidPeso molecular:446.14Ref: TM-T73295
1mg71,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg236,00€25mg485,00€50mg782,00€100mg1.305,00€
