PAI-1
O Plasminogen Activator Inhibitor-1 (PAI-1) é um inibidor de serina protease que regula a fibrinólise ao inibir o ativador de plasminogênio tecidual (tPA) e a uroquinase (uPA). Níveis elevados de PAI-1 estão associados a um aumento do risco de trombose, doenças cardiovasculares e síndrome metabólica. Inibidores de PAI-1 estão sendo investigados por seu potencial no tratamento dessas condições. Na CymitQuimica, oferecemos inibidores de PAI-1 para apoiar sua pesquisa em hematologia, saúde cardiovascular e doenças metabólicas.
Foram encontrados 31 produtos para "PAI-1".
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Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Fórmula:C32H47N5O6SPureza:99.41%Cor e Forma:White SolidPeso molecular:629.81Ref: TM-T13257
1mg60,00€2mg89,00€5mg138,00€1mL*10mM (DMSO)155,00€10mg215,00€25mg359,00€50mg510,00€100mg692,00€D-Val-Leu-Lys-AMC TFA
D-Val-Leu-Lys-AMC TFA is a selective fluorescent peptide substrate for plasmin. It is employed for the quantitative assessment of plasmin enzymatic activity. The excitation wavelength is 360-380 nm, and the emission wavelength is 440-460 nm.PAI-1-IN-2
CAS:5-Chloro-2-[[[2-[[3-(furan-2-yl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid is an oral PAI-1 inhibitor improving metabolism and hepatic steatosis.Fórmula:C21H17ClN2O6Pureza:98.78%Peso molecular:428.82UK140
UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.Fórmula:C72H105N19O25S3Cor e Forma:SolidPeso molecular:1732.91Angstrom6
CAS:Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFórmula:C39H62N10O15Pureza:99.97%Cor e Forma:SolidPeso molecular:910.97Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Fórmula:C77H118N26O25S3Cor e Forma:SolidPeso molecular:1904.11Nattokinase
CAS:Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Cor e Forma:Yellow SolidStromab
Stromab (DS9231; TS-23; CSL-301) is a human-derived IgG1 monoclonal antibody (mAb) that targets SerpinF2. It can be utilized for research in ischemic stroke, pulmonary embolism, myocardial infarction, and thrombosis. The suggested isotype control is Human IgG1 lambda, Isotype Control.6-Aminocaproic acid (Standard)
CAS:6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Fórmula:C6H13NO2Cor e Forma:SolidPeso molecular:131.173CDE-096
CAS:CDE-096 is a potent inhibitor of plasminogen activator inhibitor-1 that prevents PAI-1–mediated inactivation of tissue plasminogen activator and urokinase plasminogen activator with nanomolar potency, while maintaining activity against glycosylated and multispecies PAI-1, enabling translational research in fibrinolysis and thrombosis regulation.Fórmula:C25H20F3NO12Pureza:99.08%Cor e Forma:Yellow SolidPeso molecular:583.42Ref: TM-T25217
1mg57,00€5mg123,00€1mL*10mM (DMSO)158,00€10mg200,00€25mg423,00€50mg677,00€100mg1.063,00€Anti-SERPINE1 Antibody
Anti-SERPINE1 Antibody targets PAI-1, promoting fibrinolysis and reducing fibrosis by neutralizing its activity, and blocks PAI-1-mediated tumor immune evasion.Pureza:95%Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Fórmula:C18H20O5Pureza:99.33% - 99.86%Cor e Forma:White SolidPeso molecular:316.35Tiplaxtinin
CAS:Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Fórmula:C24H16F3NO4Pureza:99.16% - 99.93%Cor e Forma:SolidPeso molecular:439.38Ref: TM-T2030
2mg42,00€5mg62,00€1mL*10mM (DMSO)69,00€10mg90,00€25mg145,00€50mg245,00€100mg485,00€500mg1.035,00€TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Fórmula:C24H20N2O6S4Pureza:96.91%Cor e Forma:SolidPeso molecular:560.69TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Fórmula:C28H27ClN3NaO5Pureza:98.8% - 99.74%Cor e Forma:SolidPeso molecular:543.98Ref: TM-T4255
2mg39,00€5mg62,00€1mL*10mM (DMSO)67,00€10mg93,00€25mg160,00€50mg231,00€100mg334,00€200mg465,00€Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Fórmula:C16H20O6Pureza:99.8% - 99.85%Cor e Forma:SolidPeso molecular:308.33Ref: TM-T4S0592
2mg37,00€5mg52,00€1mL*10mM (DMSO)63,00€10mg73,00€25mg105,00€50mg152,00€100mg215,00€200mg320,00€UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Fórmula:C14H16ClN5O4SPureza:95.81% - 99.77%Cor e Forma:SolidPeso molecular:385.83TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Fórmula:C21H17ClN2O6Pureza:0.998% - 99.23%Cor e Forma:White SolidPeso molecular:428.82MDI-2268
CAS:MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Fórmula:C10H10F3N3O3Cor e Forma:SolidPeso molecular:277.20SK-216
CAS:SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.Fórmula:C29H29NNa2O6Pureza:98.29%Cor e Forma:SolidPeso molecular:533.52
