Acetil- CoA Carboxilase
Os inibidores da Acetil-CoA Carboxilase (ACC) são compostos que inibem a atividade da ACC, uma enzima que desempenha um papel crucial na biossíntese de ácidos graxos, convertendo acetil-CoA em malonil-CoA. A inibição da ACC pode reduzir a síntese de lipídios, tornando esses inibidores valiosos na pesquisa de distúrbios metabólicos, obesidade e câncer. Na CymitQuimica, oferecemos uma gama de inibidores da ACC para apoiar sua pesquisa em vias metabólicas, metabolismo de lipídios e desenvolvimento terapêutico.
Foram encontrados 41 produtos para "Acetil- CoA Carboxilase".
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CMS-121
CAS:CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor.Fórmula:C20H19NO3Pureza:98.71%Cor e Forma:SolidPeso molecular:321.37Spiromesifen
CAS:Spiromesifen is a useful miticide and insecticide in plant breeding. It is particuarly useful against spider mites and whiteflies in vitro.Fórmula:C23H30O4Pureza:98%Cor e Forma:SolidPeso molecular:370.48PROTAC ACC degrader-1
PROTAC ACC degrader-1 (Compound 9b), an Acetyl-CoA Carboxylase degrader, demonstrates remarkable effectiveness, with a potent activity characterized by an IC 50 of 107.8 μg/mL against Aphis craccivora.Fórmula:C37H42N4O8Cor e Forma:SolidPeso molecular:670.75Lipid Metabolism Compound Library
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Cor e Forma:Odour SolidMK-4074
CAS:MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).Fórmula:C33H31N3O6Cor e Forma:SolidPeso molecular:565.62CP-610431
CAS:CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.Fórmula:C30H37N3O2Cor e Forma:SolidPeso molecular:471.645Sethoxydim
CAS:Sethoxydim is an effective herbicide.Fórmula:C17H29NO3SCor e Forma:SolidPeso molecular:327.48Cycloxydim
CAS:Cycloxydim is a cyclohexene oxime herbicide that is used for the control of grass weeds of many agricultural and horticultural broad-leaved crops.Fórmula:C17H27NO3SCor e Forma:SolidPeso molecular:325.47(Rac)-Spirotetramat-enol
CAS:(Rac)-Spirotetramat-enol (Compound 8) serves as a ligand for target proteins, utilized in the synthesis of PROTAC ACC degrader.Fórmula:C18H23NO3Cor e Forma:SolidPeso molecular:301.38Fluazifop-P-butyl
CAS:Fluazifop-P-butyl is an arylophenoxypropionate group graminicide that functions as an inhibitor of acetyl-CoA carboxylase (ACCase)[1].Fórmula:C19H20F3NO4Cor e Forma:SolidPeso molecular:383.36Quizalofop-p-ethyl
CAS:Quizalofop-p-ethyl ((R)-Quizalofop ethyl) is a selective post-emergent herbicide for annual and perennial weeds, acetyl-CoA carboxylase (ACCase) inhibitor.Fórmula:C19H17ClN2O4Pureza:97.87%Cor e Forma:SolidPeso molecular:372.80Clodinafop-propargyl
CAS:Clodinafop-propargyl is used to control grass weeds in cereals postemergence, targeting species like Avena and Lolium.Fórmula:C17H13ClFNO4Pureza:98.85%Cor e Forma:SolidPeso molecular:349.74Cyhalofop-butyl
CAS:Cyhalofop-butyl is an ACCase (acetyl-coenzyme A carboxylase) inhibitor and herbicide that suppresses plant lipid synthesis at the meristematic level.Fórmula:C20H20FNO4Pureza:99.83%Cor e Forma:White SolidPeso molecular:357.38Olumacostat Glasaretil
CAS:Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.Fórmula:C26H43NO7Pureza:97.79% - 99.34%Cor e Forma:SolidPeso molecular:481.62Haloxyfop
CAS:(±)-Haloxyfop (Haloxyfop Acid) is a herbicide.Fórmula:C15H11ClF3NO4Pureza:99.96% - >99.99%Cor e Forma:SolidPeso molecular:361.7ND-646
CAS:ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2,Fórmula:C28H32N4O7SPureza:98.64%Cor e Forma:White SolidPeso molecular:568.64Ref: TM-TQ0243
1mg62,00€5mg177,00€1mL*10mM (DMSO)222,00€10mg289,00€25mg492,00€50mg708,00€100mg954,00€200mg1.288,00€VY-3-135
CAS:VY-3-135 is an orally active, stable and specific acetyl-CoA synthetase 2 (ACSS2) inhibitor.Cost-effective and quality-assured.Fórmula:C26H27N3O3Pureza:98.74% - 99.79%Cor e Forma:White SolidPeso molecular:429.51PF-05221304
CAS:PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.Fórmula:C28H30N4O5Pureza:98.82% - 99.50%Cor e Forma:SolidPeso molecular:502.56Ref: TM-T9209
1mg89,00€5mg164,00€10mg239,00€1mL*10mM (DMSO)241,00€25mg414,00€50mg538,00€100mg783,00€200mg1.054,00€CP-640186
CAS:CP-640186 is an isozyme-nonselective ACCase inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.Fórmula:C30H35N3O3Pureza:99.87%Cor e Forma:White SolidPeso molecular:485.62TOFA
CAS:TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).Fórmula:C19H32O4Pureza:97.52% - 98.98%Cor e Forma:Yellow SolidPeso molecular:324.45
