Cisteína Protease
Os inibidores de protease de cisteína são compostos que visam e inibem as proteases de cisteína, uma classe de enzimas que degradam proteínas ao clivar ligações peptídicas nas quais um resíduo de cisteína atua como nucleófilo. Essas enzimas estão envolvidas em vários processos fisiológicos, incluindo apoptose, resposta imune e renovação proteica. Os inibidores de protease de cisteína são cruciais para o estudo de doenças como câncer, distúrbios neurodegenerativos e infecções parasitárias. Na CymitQuimica, oferecemos inibidores de protease de cisteína para apoiar sua pesquisa em proteólise, regulação celular e descoberta de medicamentos.
Foram encontrados 110 produtos de "Cisteína Protease"
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PMSF
CAS:PMSF (Phenylmethylsulfonyl fluoride) is an irreversible inhibitor of serine/cysteine protease , preparation of cell lysates. High-Quality, Low-Cost!Fórmula:C7H7FO2SPureza:97.75% - 99.88%Cor e Forma:White To Cream SolidPeso molecular:174.19N-CBZ-Phe-Arg-AMC TFA
N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.Fórmula:C35H37F3N6O8Pureza:99.88%Cor e Forma:SolidPeso molecular:726.7Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Cor e Forma:Odour SolidRef: TM-L1100
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarCathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastaseFórmula:C24H35N5O4·xC2HF3O2Cor e Forma:SolidLeupeptin
CAS:Leupeptin, from actinomycetes, inhibits various proteases (e.g., trypsin, plasmin, kallikrein, papain, cathepsin B) but not α-chymotrypsin/thrombin.Fórmula:C20H38N6O4Pureza:98%Cor e Forma:SolidPeso molecular:426.5626,6′-Dihydroxythiobinupharidine
CAS:6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-foldFórmula:C30H42N2O4SCor e Forma:SolidPeso molecular:526.73VK13
VK13 (Compound 6) is a potent inhibitor of human cathepsin L (hCatL) and SARS-CoV-2 3CLpro (3CL-PR), with Ki values of 2.6 nM and 0.55 nM, respectively. It also exhibits activity against CoV-2, with an EC50 value of 1.25 μM.Fórmula:C24H28N4O5Cor e Forma:SolidPeso molecular:452.503Z-Phe-Tyr(tBu)-diazomethylketone
CAS:Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.Fórmula:C31H34N4O5Cor e Forma:SolidPeso molecular:542.636Z-L(D-Val)G-CHN2
Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase.Fórmula:C22H31N5O5Pureza:98%Cor e Forma:SolidPeso molecular:445.51Relacatib
CAS:Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.Fórmula:C27H32N4O6SCor e Forma:SolidPeso molecular:540.64FGA139
<p>FGA139 is an inhibitor of cysteine proteases, specifically targeting cathepsin B and L with IC50 values of 4.98 μM and 3.14 μM, respectively. It reduces the production of NO in LPS-induced RAW264.7 cells and lowers TNFα levels in microglia, demonstrating antioxidant and anti-inflammatory properties. Additionally, FGA139 enhances the secretion of neuroprotective metabolites such as purines and linoleic acid in LPS-stimulated microglia. This compound is applicable in the study of neuroinflammatory diseases.</p>Fórmula:C48H58BF2N7O5Cor e Forma:SolidPeso molecular:861.45605N-CBZ-Phe-Arg-AMC
CAS:Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.Fórmula:C33H36N6O6Pureza:98%Cor e Forma:White To Off-White PowderPeso molecular:612.68Hepcidin-1 (mouse)
CAS:Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion.Fórmula:C111H169N31O35S8Cor e Forma:SolidPeso molecular:2754.24Z-FG-NHO-Bz
CAS:Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].Fórmula:C26H25N3O6Cor e Forma:SolidPeso molecular:475.49Cathepsin D and E FRET Substrate
CAS:Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A.Fórmula:C85H122N22O19Cor e Forma:SolidPeso molecular:1756.046Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
Fluorogenic substrate for cathepsins D & E; cleaves at Phe-Phe bond; not for B, H, L. Useful for assays and studies.Cor e Forma:Odour SolidZ-Arg-Arg-βNA acetate
CAS:Z-Arg-Arg-βNA acetate serves as a sensitive dipeptide substrate for Cathepsin B protease, while demonstrating resistance to proteases H and L. This compound is crucial for differentiating non-Cathepsin B type proteins.Fórmula:C32H43N9O6Cor e Forma:SolidPeso molecular:649.74Gallinamide A TFA
CAS:Gallinamide A TFA is a peptide that exhibits linear deposition and serves as a potent inhibitor of cathepsin L (CatL) with an IC50 of 17.6 pM. It inhibits SARS-CoV-2 infection by targeting CatL (EC50: 28 nM) and also inhibits Plasmodium falciparum with an IC50 of 50 nM [1] [2].Fórmula:C33H53F3N4O9Cor e Forma:SolidPeso molecular:706.79Z-Leu-Tyr-Chloromethylketone
CAS:Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor [1].Fórmula:C24H29ClN2O5Cor e Forma:SolidPeso molecular:460.95Cathepsin L-IN-3
CAS:Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.Fórmula:C41H49N7O4SCor e Forma:SolidPeso molecular:735.94Cathepsin K inhibitor 7
Cathepsin K Inhibitor7 (compound 7) is an inhibitor of Cathepsin K, exhibiting a pKi value of 7.3. It is utilized in research on osteoporosis.Cor e Forma:Odour SolidCathepsin Inhibitor 4
<p>Cathepsin Inhibitor 4 (Compound 45) is a selective inhibitor of Cathepsin S, with a Ki value of 0.04 nM.</p>Fórmula:C24H35N3O5Peso molecular:445.25767Mpro/Cathepsin L-IN-1
Mpro/Cathepsin L-IN-1 (Compound 4d) is an inhibitor of SARS-CoV-2 Mpro and hCatL, with Ki values of 5.54 μM and 0.701 μM, respectively.Fórmula:C24H32FN3O4Peso molecular:445.23768Ac-PLVE-FMK
CAS:Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl fluoromethylketone (FMKs), serves as a cathepsin inhibitor. It is utilized in cancer research [1].Fórmula:C25H41FN4O7Pureza:98%Cor e Forma:SolidPeso molecular:528.61Dazcapistat
CAS:Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively.Fórmula:C21H18FN3O4Pureza:99.11%Cor e Forma:SolidPeso molecular:395.38Ref: TM-T9710
1mg96,00€5mg202,00€10mg305,00€25mg550,00€50mg772,00€100mg1.074,00€1mL*10mM (DMSO)224,00€Tacalcitol monohydrate
CAS:Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.Fórmula:C27H46O4Pureza:99.284%Cor e Forma:SolidPeso molecular:434.65Mpro/Cathepsin L-IN-2
Mpro/Cathepsin L-IN-2 (Compound 1) is an irreversible dual inhibitor targeting the main protease of SARS-CoV-2 (Mpro, pIC50=8.61) and human cathepsin L (hCTSL, pIC50=7.64). Mpro/Cathepsin L-IN-2 shows potential for use in research related to COVID-19 and other coronavirus infections.Cor e Forma:Odour SolidCathepsin D and E FRET Substrate acetate
Fluorogenic substrate for cathepsins D & E, not B/H/L; useful in their mechanistic studies.Fórmula:C86H124N22O21Pureza:95.63%Cor e Forma:SolidPeso molecular:1802.04PD150606
CAS:PD150606 is a calpain inhibitor with neuroprotective activity that inhibits μ-calpains and interferes with excitotoxicity-dependent motor neuron death.Fórmula:C9H7IO2SPureza:98.19%Cor e Forma:SolidPeso molecular:306.12LN5P45
LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1Fórmula:C13H15ClN2O2Cor e Forma:SolidPeso molecular:266.72JTE-607
CAS:JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.Fórmula:C25H33Cl4N3O5Pureza:97.88%Cor e Forma:SolidPeso molecular:597.36Ref: TM-T27695
1mg44,00€5mg87,00€10mg159,00€25mg328,00€50mg518,00€100mg747,00€200mg1.026,00€1mL*10mM (DMSO)115,00€E 64c
CAS:E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.Fórmula:C15H26N2O5Pureza:98.73%Cor e Forma:SolidPeso molecular:314.382-Cyanopyrimidine
CAS:2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)Fórmula:C5H3N3Pureza:99.27%Cor e Forma:Crystalline SolidPeso molecular:105.1Odanacatib
CAS:Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.Fórmula:C25H27F4N3O3SPureza:98.53% - 99.53%Cor e Forma:SolidPeso molecular:525.56Ref: TM-T6035
2mg35,00€5mg52,00€10mg80,00€25mg120,00€50mg188,00€100mg354,00€200mgA consultar1mL*10mM (DMSO)60,00€L-006235
CAS:L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.Fórmula:C24H30N6O2SPureza:99.37%Cor e Forma:SolidPeso molecular:466.6Ref: TM-T21616
2mg42,00€5mg64,00€10mg97,00€25mg187,00€50mg316,00€100mg455,00€200mg635,00€1mL*10mM (DMSO)65,00€MDL-28170
CAS:MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.Fórmula:C22H26N2O4Pureza:95.06%Cor e Forma:SolidPeso molecular:382.45Ref: TM-T2470
1mg35,00€2mg52,00€5mg74,00€10mg96,00€25mg135,00€50mg177,00€100mg299,00€1mL*10mM (DMSO)80,00€Aloxistatin
CAS:Aloxistatin (E64d) inhibits cysteine proteases, blocks calpain in platelets, and prevents blood clotting.Fórmula:C17H30N2O5Pureza:99.46% - 99.69%Cor e Forma:SolidPeso molecular:342.43Ref: TM-T6040
1mg43,00€2mg56,00€5mg88,00€10mg119,00€25mg188,00€50mg311,00€100mg502,00€500mg1.130,00€1mL*10mM (DMSO)70,00€Balicatib
CAS:Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.Fórmula:C23H33N5O2Pureza:97.78% - 98.17%Cor e Forma:White To Off-White Solid PowderPeso molecular:411.54Ref: TM-T1850
2mg42,00€5mg62,00€10mg99,00€25mg224,00€50mg378,00€100mg605,00€200mg848,00€1mL*10mM (DMSO)67,00€KGP94
CAS:KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.Fórmula:C14H12BrN3OSPureza:99.6%Cor e Forma:SolidPeso molecular:350.23Ref: TM-T27730
1mg69,00€5mg145,00€10mg226,00€25mg379,00€50mg538,00€100mg730,00€200mg979,00€1mL*10mM (DMSO)160,00€LY 3000328
CAS:LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.Fórmula:C25H29FN4O5Pureza:97.83% - 99.54%Cor e Forma:SolidPeso molecular:484.52Ref: TM-TQ0116
1mg90,00€2mg130,00€5mg198,00€10mg263,00€25mg462,00€50mg672,00€100mg945,00€1mL*10mM (DMSO)207,00€CA-074 methyl ester
CAS:CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!Fórmula:C19H31N3O6Pureza:97.26% - 99.58%Cor e Forma:SolidPeso molecular:397.47(1S,2R)-Alicapistat
CAS:(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.Fórmula:C25H27N3O4Pureza:99.60%Cor e Forma:SoildPeso molecular:433.5Ref: TM-T60150
1mg67,00€5mg150,00€10mg208,00€25mg316,00€50mg423,00€100mg567,00€1mL*10mM (DMSO)170,00€S 2160
CAS:S 2160 is a synthetic chromogenic substrate for thrombin.Fórmula:C33H40N8O6Cor e Forma:SolidPeso molecular:644.72Cathepsin Inhibitor 1
CAS:<p>Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.</p>Fórmula:C20H24ClN5O2Pureza:99.78%Cor e Forma:SolidPeso molecular:401.89DTS
CAS:DTS is a selective and isoform-specific RSK1 kinase inhibitor. It also has broad cancer therapeutic potential.Fórmula:C14H14S3Pureza:98%Cor e Forma:SolidPeso molecular:278.46JPM-OEt
CAS:JPM-OEt: broad-spectrum, covalent cysteine cathepsin inhibitor with antitumor effects.Fórmula:C20H28N2O6Pureza:98%Cor e Forma:SolidPeso molecular:392.45Calpain-2-IN-1
CAS:Calpain-2-IN-1 is a selective calpain-2 inhibitor with Ki values of 181 nM for calpain-1 and 7.8 nM for calpain-2, applicable for neurodegenerative diseases a.Fórmula:C28H37N3O7Cor e Forma:SolidPeso molecular:527.61MDL 27399
CAS:MDL 27399 suppresses human neutrophil cathepsin G.Fórmula:C26H36N4O8Cor e Forma:SolidPeso molecular:532.59AM 4299 B
CAS:AM 4299 B is a novel inhibitor of a thiol protease.Fórmula:C16H27N3O7Pureza:98%Cor e Forma:SolidPeso molecular:373.4GSK-2793660
CAS:GSK-2793660, an oral, irreversible CTSC inhibitor, aids bronchiectasis research.Fórmula:C20H27N3O3Pureza:98%Cor e Forma:SolidPeso molecular:357.45Cysteine Protease inhibitor hydrochloride
CAS:Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.Fórmula:C18H15ClN4OPureza:98%Cor e Forma:SolidPeso molecular:338.79Gü1303
CAS:Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).Fórmula:C20H22N4O3Cor e Forma:SolidPeso molecular:366.41NAAA-IN-2
CAS:<p>NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.</p>Fórmula:C11H13N3O2SCor e Forma:SolidPeso molecular:251.3SSAA09E1
CAS:SSAA09E1 blocks SARS-CoV entry, lowers ACE2-mediated HEK293T cell infection (EC50 = 6.7 μM), and inhibits cathepsin L (IC50 = 5.33 μM).Fórmula:C7H9N3S2Cor e Forma:SolidPeso molecular:199.3VEL-0230
CAS:VEL-0230 (NC-2300) is a cathespin K inhibitor boosting bone growth and reducing loss, targeting bone diseases and developed by Velcura Therapeutics.Fórmula:C14H24NNaO5Cor e Forma:SolidPeso molecular:309.33SQ 32602
CAS:SQ 32602 is a cathepsin E inhibitor.Fórmula:C32H52N3O7PCor e Forma:SolidPeso molecular:621.74GSK2793660 free base
CAS:GSK-2793660, a cathepsin C inhibitor, may treat cystic fibrosis and related lung conditions.Fórmula:C22H31N3O3Cor e Forma:SolidPeso molecular:385.5ASPER-29
CAS:ASPER-29, an Asperphenamate analog, inhibits cathepsins L/S with IC50s of 6.03/5.02 μM, useful in cancer migration/invasion research.Fórmula:C31H29BrN2O5SCor e Forma:SolidPeso molecular:621.54Dutacatib
CAS:<p>Dutacatib is an inhibitor of SARS-CoV-2 3CLpro and cathepsin K, offering antiviral properties and potential benefits in treating cancer-induced bone disease.</p>Fórmula:C23H31N7OCor e Forma:SolidPeso molecular:421.54JNJ-10329670
CAS:JNJ 10329670 is a highly potent (Ki of approximately 30 nM), nonpeptidic, noncovalent inhibitor of human cathepsin S with immunosuppressive activity.Fórmula:C30H34ClF3N6O3SCor e Forma:SolidPeso molecular:651.14Gü2602
CAS:Gü2602 inhibits the cathepsin K zymogen autocatalytic activation that is a potent, reversible inhibitor of cathepsin K (CatK) with a Ki of 0.013 nM for matureFórmula:C16H22N4O3Cor e Forma:SolidPeso molecular:318.37L-873724
CAS:L-873724: Selective, reversible cathepsin K inhibitor; IC50s—cat K: 0.2 nM, cat S: 178 nM, cat L: 264 nM, cat B: 5239 nM; inhibits bone resorption.Fórmula:C23H26F3N3O3SPureza:98%Cor e Forma:SolidPeso molecular:481.53CAA0225
CAS:CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.Fórmula:C28H29N3O5Cor e Forma:SolidPeso molecular:487.55GSK2793660 HCl
CAS:GSK2793660 is a irreversible covalent α,β-unsaturated amide based DPP1 inhibitor.Fórmula:C22H32ClN3O3Cor e Forma:SolidPeso molecular:421.96Cysteine protease inhibitor-2
CAS:Cysteine protease inhibitor from US20070032499A1; halts DCT116 at 6.5μM, PC3 at 4.4μM.Fórmula:C13H5N5OPureza:98%Cor e Forma:SolidPeso molecular:247.21Calpain Inhibitor XII
CAS:<p>Calpain Inhibitor XII (Z-L-Nva-CONH-CH2-2-Py) is a calpain I inhibitor that inhibits calpain II and cathepsin B.</p>Fórmula:C26H34N4O5Cor e Forma:SolidPeso molecular:482.57Cysteine Protease inhibitor
CAS:Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine ProteaseFórmula:C18H14N4OPureza:98%Cor e Forma:SolidPeso molecular:302.33Kgp-IN-1
CAS:Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.Fórmula:C19H24F4N4O3Pureza:98%Cor e Forma:SolidPeso molecular:432.41LHVS
CAS:<p>LHVS effectively blocks T.</p>Fórmula:C28H37N3O5SPureza:98%Cor e Forma:SolidPeso molecular:527.68CA 074
CAS:<p>CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates</p>Fórmula:C18H29N3O6Pureza:97.80%Cor e Forma:SolidPeso molecular:383.44Oxocarbazate
CAS:Oxocarbazate (CID23631927) is a subnanomolar, reversible cathepsin L inhibitor, also reducing SARS-CoV and Ebola virus entry into human cells.Fórmula:C28H33N5O6Cor e Forma:SolidPeso molecular:535.59LmCPB-IN-1
CAS:LmCPB-IN-1, compound 35, is a reversible inhibitor of LmCPB with strong binding (pKi 9.7).Fórmula:C18H30N6O2Cor e Forma:SolidPeso molecular:362.47Cathepsin L/S-IN-1
Cathepsin L/S-IN-1 inhibits Cathepsin L & S (IC50: 4.10 & 1.79 μM) and reduces metastasis in pancreatic cancer cells.Fórmula:C29H33BrN4O4SCor e Forma:SolidPeso molecular:613.57Cathepsin X-IN-1
CAS:<p>Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].</p>Fórmula:C15H13N3O3SPureza:99.34%Cor e Forma:SolidPeso molecular:315.35JNJ-10311795
CAS:JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.Fórmula:C40H35N2O6PPureza:97.43%Cor e Forma:SolidPeso molecular:670.69Z-LVG
CAS:Z-LVG, an irreversible cysteine protease inhibitor and a tripeptide derivative of cystatin C, serves as an inhibitor of viral replication and is utilized inFórmula:C21H31N3O6Cor e Forma:SolidPeso molecular:421.49Cathepsin K inhibitor 3
CAS:Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.Fórmula:C30H31FN4O4SCor e Forma:SolidPeso molecular:562.65Cathepsin Inhibitor 2
CAS:Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).Fórmula:C19H21F6N3OPureza:98%Cor e Forma:SolidPeso molecular:421.38Z-FG-NHO-BzOME
CAS:Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,Fórmula:C27H27N3O7Cor e Forma:SolidPeso molecular:505.52Z-DEVD-CMK
CAS:Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].Fórmula:C27H35ClN4O12Cor e Forma:SolidPeso molecular:643.04MeOSuc-AAPV-CMK
CAS:MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediatedFórmula:C22H35ClN4O7Cor e Forma:SolidPeso molecular:502.99SPR38
SPR38: SARS-CoV-2 protease inhibitor with Ki 0.260 μM; also blocks hCatL (Ki 1.92 μM) and hCatB (Ki 11.1 μM).Fórmula:C24H33N3O5Cor e Forma:SolidPeso molecular:443.54(Rac)-Neurodegenerative Disorder-Targeting Compound 1
CAS:(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.Fórmula:C28H28N4O4Cor e Forma:SolidPeso molecular:484.55Petesicatib
CAS:Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.Fórmula:C25H23F6N5O4SPureza:99.76%Cor e Forma:SolidPeso molecular:603.54Ref: TM-T16474
1mg105,00€5mg250,00€10mg393,00€25mg777,00€50mg1.198,00€100mg1.549,00€200mg2.080,00€1mL*10mM (DMSO)331,00€SQ 32056
CAS:SQ 32056 is a cathepsin E inhibitor.Fórmula:C37H56N4O5Pureza:98%Cor e Forma:SolidPeso molecular:636.86MPI8
CAS:MPI8 is a SARS-CoV-2 Protease inhibitor (IC50 = 105 nM).Fórmula:C32H48N4O7Cor e Forma:SolidPeso molecular:600.75ABP 25
CAS:ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.Fórmula:C55H66ClN5O3Cor e Forma:SolidPeso molecular:880.6SID 26681509
CAS:SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).Fórmula:C27H33N5O5SPureza:99.18%Cor e Forma:SolidPeso molecular:539.65Ref: TM-T12909
1mg66,00€5mg144,00€10mg216,00€25mg437,00€50mg652,00€100mg930,00€1mL*10mM (DMSO)172,00€MK-0674
CAS:MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.Fórmula:C26H27F6N3O2Pureza:97.3% - 99.91%Cor e Forma:SolidPeso molecular:527.5VBY-825
CAS:VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.Fórmula:C23H29F4N3O5SPureza:99.91%Cor e Forma:SolidPeso molecular:535.55SID 26681509 quarterhydrate
SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).Fórmula:C27H35N5O6SCor e Forma:SolidPeso molecular:544.16RO5461111
CAS:RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.Fórmula:C27H24F6N4O4SCor e Forma:SolidPeso molecular:614.56Cathepsin C-IN-3
Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).Fórmula:C28H21F3N6OSCor e Forma:SolidPeso molecular:546.57BI-1915
CAS:<p>BI-1915 is a selective inhibitor of Cathepsin S, with an IC50 of 17 nM. It is utilized in the research of autoimmune diseases.</p>Fórmula:C21H37N5O3Cor e Forma:SolidPeso molecular:407.55Cathepsin K inhibitor 2
CAS:Cathepsin K inhibitor 2 targets CTSK gene, may treat osteoporosis and osteoarthritis, detailed in patent WO2021147882A1.Fórmula:C30H33F4N5O3Cor e Forma:SolidPeso molecular:587.61ONO-5334
CAS:ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).Fórmula:C21H34N4O4SPureza:98.22% - 99.60%Cor e Forma:SolidPeso molecular:438.58Cathepsin C-IN-4
Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).Fórmula:C21H14ClF3N4SCor e Forma:SolidPeso molecular:446.88AEP-IN-1
APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.Fórmula:C18H27N3O3Cor e Forma:SolidPeso molecular:333.43CTSL/CAPN1-IN-2
CAS:CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].Fórmula:C34H40N4O6Cor e Forma:SolidPeso molecular:600.7SAR-114137
CAS:SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.Fórmula:C25H34N4O7SPureza:99.09% - 99.91%Cor e Forma:SolidPeso molecular:534.63
