Cisteína Protease
Os inibidores de protease de cisteína são compostos que visam e inibem as proteases de cisteína, uma classe de enzimas que degradam proteínas ao clivar ligações peptídicas nas quais um resíduo de cisteína atua como nucleófilo. Essas enzimas estão envolvidas em vários processos fisiológicos, incluindo apoptose, resposta imune e renovação proteica. Os inibidores de protease de cisteína são cruciais para o estudo de doenças como câncer, distúrbios neurodegenerativos e infecções parasitárias. Na CymitQuimica, oferecemos inibidores de protease de cisteína para apoiar sua pesquisa em proteólise, regulação celular e descoberta de medicamentos.
Foram encontrados 110 produtos de "Cisteína Protease"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Mpro/Cathepsin L-IN-1
Mpro/Cathepsin L-IN-1 (Compound 4d) is an inhibitor of SARS-CoV-2 Mpro and hCatL, with Ki values of 5.54 μM and 0.701 μM, respectively.Fórmula:C24H32FN3O4Peso molecular:445.23768Ac-PLVE-FMK
CAS:Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl fluoromethylketone (FMKs), serves as a cathepsin inhibitor. It is utilized in cancer research [1].Fórmula:C25H41FN4O7Pureza:98%Cor e Forma:SolidPeso molecular:528.61Z-Phe-Tyr(tBu)-diazomethylketone
CAS:Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.Fórmula:C31H34N4O5Cor e Forma:SolidPeso molecular:542.636Z-L(D-Val)G-CHN2
Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase.Fórmula:C22H31N5O5Pureza:98%Cor e Forma:SolidPeso molecular:445.51Relacatib
CAS:Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.Fórmula:C27H32N4O6SCor e Forma:SolidPeso molecular:540.64Cathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastaseFórmula:C24H35N5O4·xC2HF3O2Cor e Forma:SolidLeupeptin
CAS:Leupeptin, from actinomycetes, inhibits various proteases (e.g., trypsin, plasmin, kallikrein, papain, cathepsin B) but not α-chymotrypsin/thrombin.Fórmula:C20H38N6O4Pureza:98%Cor e Forma:SolidPeso molecular:426.562Z-FG-NHO-Bz
CAS:Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].Fórmula:C26H25N3O6Cor e Forma:SolidPeso molecular:475.49Cathepsin D and E FRET Substrate acetate
Fluorogenic substrate for cathepsins D & E, not B/H/L; useful in their mechanistic studies.Fórmula:C86H124N22O21Pureza:95.63%Cor e Forma:SolidPeso molecular:1802.04LN5P45
LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1Fórmula:C13H15ClN2O2Cor e Forma:SolidPeso molecular:266.72L-006235
CAS:L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.Fórmula:C24H30N6O2SPureza:99.37%Cor e Forma:SolidPeso molecular:466.6Ref: TM-T21616
2mg42,00€5mg64,00€10mg97,00€25mg187,00€50mg316,00€100mg455,00€200mg635,00€1mL*10mM (DMSO)65,00€Aloxistatin
CAS:Aloxistatin (E64d) inhibits cysteine proteases, blocks calpain in platelets, and prevents blood clotting.Fórmula:C17H30N2O5Pureza:99.46% - 99.69%Cor e Forma:SolidPeso molecular:342.43Ref: TM-T6040
1mg43,00€2mg56,00€5mg88,00€10mg119,00€25mg188,00€50mg311,00€100mg502,00€500mg1.130,00€1mL*10mM (DMSO)70,00€Balicatib
CAS:Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.Fórmula:C23H33N5O2Pureza:97.78% - 98.17%Cor e Forma:White To Off-White Solid PowderPeso molecular:411.54Ref: TM-T1850
2mg42,00€5mg62,00€10mg99,00€25mg224,00€50mg378,00€100mg605,00€200mg848,00€1mL*10mM (DMSO)67,00€MDL-28170
CAS:MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.Fórmula:C22H26N2O4Pureza:95.06%Cor e Forma:SolidPeso molecular:382.45Ref: TM-T2470
1mg35,00€2mg52,00€5mg74,00€10mg96,00€25mg135,00€50mg177,00€100mg299,00€1mL*10mM (DMSO)80,00€Odanacatib
CAS:Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.Fórmula:C25H27F4N3O3SPureza:98.53% - 99.53%Cor e Forma:SolidPeso molecular:525.56Ref: TM-T6035
2mg35,00€5mg52,00€10mg80,00€25mg120,00€50mg188,00€100mg354,00€200mgA consultar1mL*10mM (DMSO)60,00€KGP94
CAS:KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.Fórmula:C14H12BrN3OSPureza:99.6%Cor e Forma:SolidPeso molecular:350.23Ref: TM-T27730
1mg65,00€5mg138,00€10mg215,00€25mg359,00€50mg510,00€100mg692,00€200mg928,00€1mL*10mM (DMSO)152,00€2-Cyanopyrimidine
CAS:2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)Fórmula:C5H3N3Pureza:99.27%Cor e Forma:Crystalline SolidPeso molecular:105.1LY 3000328
CAS:LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.Fórmula:C25H29FN4O5Pureza:97.83% - 99.54%Cor e Forma:SolidPeso molecular:484.52Ref: TM-TQ0116
1mg90,00€2mg130,00€5mg198,00€10mg263,00€25mg462,00€50mg672,00€100mg945,00€1mL*10mM (DMSO)207,00€CA-074 methyl ester
CAS:CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!Fórmula:C19H31N3O6Pureza:97.26% - 99.58%Cor e Forma:SolidPeso molecular:397.47E 64c
CAS:E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.Fórmula:C15H26N2O5Pureza:98.73%Cor e Forma:SolidPeso molecular:314.38
