DPP-4
Os inibidores de DPP-4 são compostos que inibem a Dipeptidil Peptidase-4, uma enzima envolvida na inativação de hormonas incretinas, que regulam o metabolismo da glicose. Ao inibir a DPP-4, estes compostos ajudam a prolongar a ação das hormonas incretinas, aumentando a secreção de insulina e reduzindo os níveis de glicose no sangue. Os inibidores de DPP-4 são amplamente utilizados no tratamento do diabetes tipo 2 e em pesquisas focadas em distúrbios metabólicos. Na CymitQuimica, oferecemos inibidores de DPP-4 para apoiar sua pesquisa em endocrinologia, manejo do diabetes e doenças metabólicas.
Foram encontrados 94 produtos para "DPP-4".
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Retagliptin Phosphate
CAS:Retagliptin Phosphate (SP 2086) is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.Fórmula:C19H21F6N4O7PPureza:98.70%Cor e Forma:SolidPeso molecular:562.3568Begelomab
CAS:Begelomab (SAND-26) is a mouse-derived monoclonal antibody targeting DPP-4/CD26. Begelomab can be used to study severe refractory inflammatory myopathies.Pureza:97.8% (SDS-PAGE); 98.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:146.20 kDa (Predicted)DBPR108
CAS:DBPR108 is an orally bioavailable dipeptide-derived DPP4 inhibitor (IC50: 15 nM) and it has no inhibition on DDP8 and DPP9.Fórmula:C16H25FN4O2Pureza:99.68%Cor e Forma:SolidPeso molecular:324.3937Denagliptin
CAS:Denagliptin is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor for the treatment of endocrine Ü metabolic diseases and can be used in the study ofFórmula:C20H18F3N3OPureza:99.12%Cor e Forma:SolidPeso molecular:373.3716Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Fórmula:C18H27N3O3Pureza:99.52%Cor e Forma:SolidPeso molecular:333.4253Trelagliptin
CAS:Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.Fórmula:C18H20FN5O2Pureza:98.88%Cor e Forma:SolidPeso molecular:357.3821Fotagliptin
CAS:Fotagliptin is a dipeptidyl peptidase IV inhibitor.Fórmula:C17H19FN6OCor e Forma:SolidPeso molecular:342.37Linagliptin Methyldimer
CAS:Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.Fórmula:C50H56N16O4Pureza:99.91%Cor e Forma:SolidPeso molecular:945.0844AMG-222
CAS:AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.Fórmula:C32H39N9O3Cor e Forma:SolidPeso molecular:597.71(-)-Sitagliptin Carbamoyl Glucuronide
CAS:Minor phase II metabolite of DPP-4 inhibitor sitagliptin, found in rat and dog plasma.Fórmula:C23H23F6N5O9Cor e Forma:SolidPeso molecular:627.453DPP-4/GPR119 modulator 1
CAS:Orally active DPP-4 inhibitor/GPR119 agonist, Compound 22 lowers glucose, moderate hERG inhibition, IC50 4.9 µM, for diabetes research.Fórmula:C30H39ClN10O3Cor e Forma:SolidPeso molecular:623.15Sitagliptin fenilalanil hydrochloride
CAS:Sitagliptin fenilalanil hydrochloride is an orally active DPP-4 inhibitor. Sitagliptin fenilalanil hydrochloride is used in diabetes research.Fórmula:C25H25ClF6N6O2Pureza:98.32%Cor e Forma:White SolidPeso molecular:590.955-Hydroxy saxagliptin hydrochloride
5-Hydroxy saxagliptin hydrochloride is the active metabolite of Saxagliptin and serves as a potent and selective DPP-4 inhibitor. The Ki values for 5-Hydroxy saxagliptin hydrochloride are 2.6 nM in humans and 2.9 nM in cynomolgus monkeys. This compound is applicable in the research of type 2 diabetes.Talabostat isomer mesylate
Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).Fórmula:C10H23BN2O6SPureza:98%Cor e Forma:SolidPeso molecular:310.18SGLT2-IN-6
SGLT2-IN-6 (Compound 101) is an orally active SGLT2 inhibitor with IC₅₀ values of 0.8 nM, 6.7 nM, and 72 nM for SGLT2, SGLT1, and DPP4, respectively. In diabetic rat models, SGLT2-IN-6 controls blood glucose levels and increases active GLP-1 levels. It is suitable for research on type 2 diabetes.HAEGT
CAS:HAEGT is the first N-terminal 1-5 residues of GLP-1 peptide.Fórmula:C20H31N7O9Pureza:98%Cor e Forma:SolidPeso molecular:513.5016SGLT2-IN-5
SGLT2-IN-5 (Compound 99) is an orally active SGLT2 inhibitor with IC₅₀ values of 0.8 nM for SGLT2, 23 nM for SGLT1, and 58 nM for DPP4. In diabetic rat models, SGLT2-IN-5 effectively regulates blood glucose and increases the levels of active GLP-1. It is suitable for research on type 2 diabetes.Dutogliptin tartrate
CAS:Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Fórmula:C14H26BN3O9Pureza:98%Cor e Forma:SolidPeso molecular:391.18Ellipyrone A
Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).Fórmula:C25H34O8Cor e Forma:SolidPeso molecular:462.53Camegliptin
CAS:Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.Fórmula:C20H28FN3O3Cor e Forma:SolidPeso molecular:377.45
