Células - tronco
Os inibidores de células-tronco são compostos que atuam especificamente nas células-tronco e em suas vias de sinalização, afetando sua capacidade de autorrenovação e diferenciação. Esses inibidores são cruciais em pesquisas focadas no controle do comportamento das células-tronco, na compreensão dos processos de desenvolvimento e no desenvolvimento de terapias para doenças como o câncer, onde se acredita que as células-tronco desempenhem um papel fundamental. Na CymitQuimica, oferecemos uma variedade de inibidores de células-tronco para apoiar sua pesquisa em medicina regenerativa, biologia do desenvolvimento e oncologia.
Foram encontrados 485 produtos de "Células - tronco"
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SB-772077B dihydrochloride
CAS:<p>SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).</p>Fórmula:C15H20Cl2N8O2Pureza:98%Cor e Forma:SolidPeso molecular:415.28inS3-54-A26
CAS:<p>inS3-54-A26 is an inhibitor of the DNA-binding domain of STAT3. inS3-54-A26 suppresses tumor growth, metastasis and the gene expression of STAT3.</p>Fórmula:C25H19ClN2O2Pureza:99.57%Cor e Forma:SolidPeso molecular:414.88TEAD-IN-6
CAS:<p>TEAD-IN-6 (Example 11-1) is a TEAD modulator that inhibits the YAP1/TAZ-TEAD interaction, and has applications in cancer research [1].</p>Fórmula:C19H17F3N4O3SPureza:98%Cor e Forma:SolidPeso molecular:438.42VT103
CAS:<p>VT103, an oral TEAD1 palmitoylation inhibitor, shows promise against various cancers by disrupting YAP/TAZ-TEAD interactions.</p>Fórmula:C18H17F3N4O2SPureza:99.58%Cor e Forma:SolidPeso molecular:410.41γ-secretase modulator 1
CAS:<p>gamma-secretase modulator 1 is a modulator of γ secretase and can be used in studies about the treatment of Alzheimer's disease.</p>Fórmula:C24H24N4OSPureza:99.75% - 99.96%Cor e Forma:SolidPeso molecular:416.54GSK3-IN-2
CAS:<p>GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.</p>Fórmula:C17H19N3OSPureza:98.8%Cor e Forma:SolidPeso molecular:313.42JAK3i
CAS:<p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>Fórmula:C18H15FN4O3Pureza:98.61% - 99.81%Cor e Forma:SolidPeso molecular:354.34BRD0209
CAS:<p>BRD0209 is a highly selective and potent GSK3 inhibitor.</p>Fórmula:C22H25N3OPureza:99.92%Cor e Forma:SolidPeso molecular:347.45CAY10746
CAS:<p>CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.</p>Fórmula:C26H23N3O5Pureza:99.04%Cor e Forma:SolidPeso molecular:457.48CJJ300
CAS:<p>CJJ300 is a TGF-β inhibitor disrupting TGF-β-TβR complex formation, with an IC50 of 5.3 μM, and halts cell migration.</p>Fórmula:C30H33N3Pureza:99.80%Cor e Forma:SolidPeso molecular:435.6JAK3/BTK-IN-1
CAS:<p>JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important</p>Fórmula:C25H28N8OPureza:97.89%Cor e Forma:SolidPeso molecular:456.54AF-2112
<p>AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2.</p>Fórmula:C21H18FNO3Pureza:98%Cor e Forma:SolidPeso molecular:351.37Aβ42-IN-2
CAS:<p>Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].</p>Fórmula:C24H26N6O2Pureza:98.09% - 99.87%Cor e Forma:SolidPeso molecular:430.5JA310
CAS:<p>JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].</p>Fórmula:C17H19N7OCor e Forma:SolidPeso molecular:337.383F8
CAS:<p>3F8 is a selective GSK-3β inhibitor that can be used as a new tool and potential therapeutic candidate compound for GSK3-related diseases, and can be used in</p>Fórmula:C15H14N2O4Pureza:98.14% - 98.25%Cor e Forma:SolidPeso molecular:286.28TGFβRI-IN-1
CAS:<p>TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII,</p>Fórmula:C20H14D3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:362.4JAK1-IN-4
CAS:<p>JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).</p>Fórmula:C26H32FN9O2Pureza:98%Cor e Forma:SolidPeso molecular:521.59JAK-IN-11
CAS:<p>JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.</p>Fórmula:C23H22FN5O4SPureza:99.75%Cor e Forma:SolidPeso molecular:483.52JAK3/BTK-IN-2
CAS:<p>JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.</p>Fórmula:C25H32N8O2Pureza:99.64% - 99.87%Cor e Forma:SolidPeso molecular:476.57Chromenone 1
CAS:<p>Chromenone 1 is a potent potentiator of osteogenic bone morphogenetic protein (BMP).</p>Fórmula:C18H10F3N3O2Pureza:99.83% - 99.93%Cor e Forma:SolidPeso molecular:357.29
