Células - tronco
Os inibidores de células-tronco são compostos que atuam especificamente nas células-tronco e em suas vias de sinalização, afetando sua capacidade de autorrenovação e diferenciação. Esses inibidores são cruciais em pesquisas focadas no controle do comportamento das células-tronco, na compreensão dos processos de desenvolvimento e no desenvolvimento de terapias para doenças como o câncer, onde se acredita que as células-tronco desempenhem um papel fundamental. Na CymitQuimica, oferecemos uma variedade de inibidores de células-tronco para apoiar sua pesquisa em medicina regenerativa, biologia do desenvolvimento e oncologia.
Foram encontrados 483 produtos de "Células - tronco"
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Verosudil
CAS:<p>Verosudil (AR-12286), a ROCK1/2 inhibitor (Ki: 2 nM), lowers intraocular pressure in mice by enhancing aqueous outflow.</p>Fórmula:C17H17N3O2SPureza:99.72%Cor e Forma:SolidPeso molecular:327.4IBS008738
CAS:<p>IBS008738 is a TAZ activator that stabilises TAZ and increases unphosphorylated TAZ levels in C2C12 cells, upregulates MyoD-dependent gene transcription.</p>Fórmula:C22H22N4O2Pureza:99.44%Cor e Forma:SolidPeso molecular:374.44Belumosudil mesylate
CAS:<p>Belumosudil mesylate (KD025 mesylate) is a ROCK2 inhibitor with antifibrotic activity, and can be used in chronic graft-versus-host disease research.</p>Fórmula:C27H28N6O5SPureza:98.73%Cor e Forma:SolidPeso molecular:548.61SGC-CK2-1
CAS:<p>SGC-CK2-1, a CK2 inhibitor, is a inducer of insulin production and secretion in pancreatic β-cells.</p>Fórmula:C20H21N7OPureza:99.41%Cor e Forma:SolidPeso molecular:375.43GSK269962A hydrochloride
CAS:<p>GSK269962A hydrochloride (GSK 269962 hydrochloride) is a ROCK inhibitor with anti-inflammatory and vasodilatory effects and inhibits ROCK1 and ROCK2.</p>Fórmula:C29H31ClN8O5Cor e Forma:SolidPeso molecular:607.06Stafib-1
CAS:Stafib-1 is a selective inhibitor of STAT5β targeting SH2 domain with an IC50 of 154 nM and a Ki of 44 nM.Fórmula:C26H24N2O11P2Pureza:97.18%Cor e Forma:SolidPeso molecular:602.42CMD178 TFA
<p>CMD178 (TFA) is a lead peptide that consistently reduces the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling.</p>Fórmula:C48H60F3N9O9Pureza:>99.99%Cor e Forma:SolidPeso molecular:964.05Teplinovivint
CAS:<p>Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathy</p>Fórmula:C25H26N6O2Pureza:97.21%Cor e Forma:SolidPeso molecular:442.51S3I-201
CAS:<p>S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.</p>Fórmula:C16H15NO7SPureza:97.83%Cor e Forma:SolidPeso molecular:365.36PF-670462
CAS:<p>PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.</p>Fórmula:C19H22Cl2FN5Pureza:99.42% - 99.72%Cor e Forma:SolidPeso molecular:410.32AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Fórmula:C19H18N4O2Pureza:97.72% - 99.75%Cor e Forma:SolidPeso molecular:334.372,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Fórmula:C16H13Cl2N3O2Pureza:98.77%Cor e Forma:SolidPeso molecular:350.2GSK429286A
CAS:<p>GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).</p>Fórmula:C21H16F4N4O2Pureza:97.68% - 98.49%Cor e Forma:SolidPeso molecular:432.37SH-4-54
CAS:SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.Fórmula:C29H27F5N2O5SPureza:98% - 99.12%Cor e Forma:SolidPeso molecular:610.59ROCK-IN-2
CAS:<p>ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.</p>Fórmula:C18H13ClF2N6OPureza:97.29%Cor e Forma:SolidPeso molecular:402.79Wnt pathway activator 1
CAS:Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.Fórmula:C18H16O4Pureza:99.93%Cor e Forma:SolidPeso molecular:296.32GS87
CAS:<p>GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.</p>Fórmula:C16H11N5O2SPureza:98.86%Cor e Forma:SolidPeso molecular:337.36FH535
CAS:<p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>Fórmula:C13H10Cl2N2O4SPureza:98.25% - 99.5%Cor e Forma:SolidPeso molecular:361.2Tegatrabetan
CAS:<p>Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.</p>Fórmula:C28H36N4O6S2Pureza:98.01% - 99.18%Cor e Forma:SolidPeso molecular:588.74IWP-O1
CAS:IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.Fórmula:C26H20N6OPureza:99.12%Cor e Forma:SolidPeso molecular:432.48
