Receptor do Factor de Crescimento Fibroblasto (FGFR)
Os inibidores de FGFR (receptores do fator de crescimento de fibroblastos) são terapias direcionadas que bloqueiam a atividade dos FGFRs, que estão envolvidos na proliferação celular, diferenciação e angiogênese. A sinalização de FGFR contribui para a formação de novos vasos sanguíneos em tumores, promovendo seu crescimento e sobrevivência. Inibir FGFR pode, portanto, reduzir a angiogênese e a progressão tumoral. Na CymitQuimica, oferecemos uma gama de inibidores de FGFR de alta qualidade para apoiar sua pesquisa em câncer, biologia do desenvolvimento e angiogênese.
Foram encontrados 183 produtos para "Receptor do Factor de Crescimento Fibroblasto (FGFR)".
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FGFR1/DDR2 inhibitor 1
CAS:FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108Fórmula:C28H22F3N5OPureza:99.43%Cor e Forma:White SolidPeso molecular:501.5Ref: TM-T11279
1mg96,00€5mg205,00€1mL*10mM (DMSO)227,00€10mg334,00€25mg550,00€50mg760,00€100mg1.108,00€Lucitanib
CAS:Lucitanib (E-3810) is a VEGFR/FGFR inhibitor targeting VEGFR1-3 and FGFR1-2 with IC50s 7-82.5 nM.Fórmula:C26H25N3O4Pureza:96.13%Cor e Forma:SolidPeso molecular:443.49Ref: TM-T15185
1mg46,00€2mg59,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg255,00€50mg462,00€100mg672,00€2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Fórmula:C21H15ClF4N4O3Pureza:98%Cor e Forma:SolidPeso molecular:482.8154Ref: IN-DA00ICN3
100gA consultar10mg30,00€50mg46,00€100mg56,00€250mg69,00€500mg100,00€1g131,00€5g255,00€50g617,00€10g619,00€Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Cor e Forma:SolidPeso molecular:437.52Aprutumab
CAS:Aprutumab, a human FGFR2 monoclonal antibody, targets FGFR2-IIIB/C and is used in antibody-drug conjugates.Pureza:98.69% (SEC-HPLC) - 98.69% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:150 kDaAmlexanox
CAS:Amlexanox (AA673) treats ulcers by blocking leukotrienes, histamine, reducing inflammation, pain, and healing time.Fórmula:C16H14N2O4Pureza:99.67% - ≥95%Cor e Forma:SolidPeso molecular:298.29Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Fórmula:C21H19ClN4O4Pureza:98.46% - 99.96%Cor e Forma:White SolidPeso molecular:426.85Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
CAS:Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist.Fórmula:C26H32N4O8Pureza:99.83% - >99.99%Cor e Forma:SolidPeso molecular:528.55Gunagratinib
CAS:Gunagratinib (ICP-192) is a pan-FGFR inhibitor, useful in research on FGFR-related diseases.Fórmula:C22H25N5O4Pureza:99.68%Cor e Forma:SolidPeso molecular:423.47Ref: TM-T39682
1mg69,00€5mg147,00€1mL*10mM (DMSO)164,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€Triamcinolone acetonide
CAS:Triamcinolone acetonide (Azmacort) is a Corticosteroid.Fórmula:C24H31FO6Pureza:99.61% - 99.91%Cor e Forma:SolidPeso molecular:434.50Formononetin
CAS:Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.Fórmula:C16H12O4Pureza:97.39% - 99.94%Cor e Forma:SolidPeso molecular:268.26Ferulic Acid
CAS:Ferulic Acid (Coniferic acid) is a highly abundant phenolic phytochemical and a organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong.Fórmula:C10H10O4Pureza:99.72%Cor e Forma:SolidPeso molecular:194.18LC-MB12
CAS:LC-MB12 is a PROTAC FGFR2 compound that degrades FGFR2 and can be used to study gastric cancer.Fórmula:C43H44Cl2N10O8Pureza:99.16%Cor e Forma:SolidPeso molecular:899.78Pemigatinib
CAS:Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).Fórmula:C24H27F2N5O4Pureza:99.57% - 99.95%Cor e Forma:White SolidPeso molecular:487.52,5-Dihydroxybenzoic acid
CAS:2,5-Dihydroxybenzoic acid (Gentisic acid) is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity.Fórmula:C7H6O4Pureza:99.63%Cor e Forma:White SolidPeso molecular:154.12bFGF (119-126)
CAS:bFGF (119-126) is a biologically active peptide corresponding to the residues of human, bovine (119-126), mouse, rat (118-125), and Heparin-Binding GrowthFórmula:C44H76N14O12Cor e Forma:SolidPeso molecular:993.16FGFR1/VEGFR2-IN-1
FGFR1/VEGFR2-IN-1 (compound 2b) is an inhibitor of both FGFR1 and VEGFR2, applicable in cancer research [1].Fórmula:C26H27N4O6PPureza:98%Cor e Forma:SolidPeso molecular:522.49E7090
CAS:E-7090 is a fibroblast growth factor receptor inhibitor. E-7090 is a selective inhibitor of the tyrosine kinase activities of FGFR1, -2, and -3.Fórmula:C32H37N5O6Cor e Forma:SolidPeso molecular:587.67IMC-D11
IMC-D11 is a fully human anti-FGFR3 mAb that inhibits tumor cell proliferation by blocking ligand binding and receptor phosphorylation.Cor e Forma:Odour Liquid
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