Receptor do Factor de Crescimento Fibroblasto (FGFR)
Os inibidores de FGFR (receptores do fator de crescimento de fibroblastos) são terapias direcionadas que bloqueiam a atividade dos FGFRs, que estão envolvidos na proliferação celular, diferenciação e angiogênese. A sinalização de FGFR contribui para a formação de novos vasos sanguíneos em tumores, promovendo seu crescimento e sobrevivência. Inibir FGFR pode, portanto, reduzir a angiogênese e a progressão tumoral. Na CymitQuimica, oferecemos uma gama de inibidores de FGFR de alta qualidade para apoiar sua pesquisa em câncer, biologia do desenvolvimento e angiogênese.
Foram encontrados 185 produtos para "Receptor do Factor de Crescimento Fibroblasto (FGFR)".
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Regorafenib
CAS:Fórmula:C21H15ClF4N4O3Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:482.82PD-161570
CAS:Fórmula:C26H35Cl2N7OPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:532.51Methyl 1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylate
CAS:Fórmula:C21H19NO5Pureza:>95.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:365.39Nintedanib
CAS:Fórmula:C31H33N5O4Pureza:>95.0%(HPLC)(T)Cor e Forma:White to Yellow to Yellow green powder to crystalPeso molecular:539.64PD 173074
CAS:Fórmula:C28H41N7O3Pureza:>95.0%(HPLC)Cor e Forma:White to Yellow to Orange powder to crystalPeso molecular:523.682-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Fórmula:C21H15ClF4N4O3Pureza:98%Cor e Forma:SolidPeso molecular:482.8154Ref: IN-DA00ICN3
100gA consultar10mg28,00€50mg43,00€100mg52,00€250mg65,00€500mg94,00€1g124,00€5g283,00€10g583,00€50g615,00€2,5-Dihydroxybenzoic acid
CAS:2,5-Dihydroxybenzoic acid (Gentisic acid) is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity.Fórmula:C7H6O4Pureza:99.63%Cor e Forma:White SolidPeso molecular:154.1201LC-MB12
CAS:LC-MB12 is a PROTAC FGFR2 compound that degrades FGFR2 and can be used to study gastric cancer.Fórmula:C43H44Cl2N10O8Pureza:99.16%Cor e Forma:SolidPeso molecular:899.78Pemigatinib
CAS:Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).Fórmula:C24H27F2N5O4Pureza:99.57% - 99.95%Cor e Forma:White SolidPeso molecular:487.4991Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Fórmula:C21H19ClN4O4Pureza:98.46% - 99.96%Cor e Forma:White SolidPeso molecular:426.85Lucitanib
CAS:Lucitanib (E-3810) is a VEGFR/FGFR inhibitor targeting VEGFR1-3 and FGFR1-2 with IC50s 7-82.5 nM.Fórmula:C26H25N3O4Pureza:97.33%Cor e Forma:SolidPeso molecular:443.4944Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
CAS:Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist.Fórmula:C26H32N4O8Pureza:99.83% - >99.99%Cor e Forma:SolidPeso molecular:528.5543Formononetin
CAS:Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.Fórmula:C16H12O4Pureza:97.39% - 99.94%Cor e Forma:SolidPeso molecular:268.2641Gunagratinib
CAS:Gunagratinib (ICP-192) is a pan-FGFR inhibitor, useful in research on FGFR-related diseases.Fórmula:C22H25N5O4Pureza:99.68%Cor e Forma:SolidPeso molecular:423.465Ferulic Acid
CAS:Ferulic Acid (Coniferic acid) is a highly abundant phenolic phytochemical and a organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong.Fórmula:C10H10O4Pureza:99.72%Cor e Forma:SolidPeso molecular:194.184FGFR1/DDR2 inhibitor 1
CAS:FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108Fórmula:C28H22F3N5OPureza:99.43%Cor e Forma:White SolidPeso molecular:501.5024Amlexanox
CAS:Amlexanox (AA673) treats ulcers by blocking leukotrienes, histamine, reducing inflammation, pain, and healing time.Fórmula:C16H14N2O4Pureza:99.67% - ≥95%Cor e Forma:SolidPeso molecular:298.29Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Cor e Forma:SolidPeso molecular:437.518FGFR1/VEGFR2-IN-1
FGFR1/VEGFR2-IN-1 (compound 2b) is an inhibitor of both FGFR1 and VEGFR2, applicable in cancer research [1].Fórmula:C26H27N4O6PPureza:98%Cor e Forma:SolidPeso molecular:522.49E7090
CAS:E-7090 is a fibroblast growth factor receptor inhibitor. E-7090 is a selective inhibitor of the tyrosine kinase activities of FGFR1, -2, and -3.Fórmula:C32H37N5O6Cor e Forma:SolidPeso molecular:587.6661
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