VEGFR
Os inibidores do Receptor do Fator de Crescimento Endotelial Vascular (VEGFR) são compostos que bloqueiam a sinalização do VEGFR, um receptor chave na via VEGF, crucial para a angiogênese. Os inibidores de VEGFR impedem a formação de novos vasos sanguíneos que fornecem nutrientes e oxigênio aos tumores, inibindo assim o crescimento tumoral. Esses inibidores são amplamente utilizados na terapia contra o câncer e na pesquisa para estudar os mecanismos da angiogênese e desenvolver tratamentos anticâncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de VEGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 239 produtos de "VEGFR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
JK-P3
CAS:Fórmula:C18H17N3O3Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:323.35Nintedanib
CAS:Fórmula:C31H33N5O4Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Yellow to Yellow green powder to crystalPeso molecular:539.64Sunitinib Malate
CAS:Fórmula:C22H27FN4O2·C4H6O5Pureza:>98.0%(HPLC)Cor e Forma:Light yellow to Brown powder to crystalPeso molecular:532.57Cediranib
CAS:Fórmula:C25H27FN4O3Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:450.51Pazopanib
CAS:Fórmula:C21H23N7O2SPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:437.52Linifanib
CAS:Fórmula:C21H18FN5OPureza:>95.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:375.41Pazopanib Hydrochloride
CAS:Fórmula:C21H23N7O2S·HClPureza:>95.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:473.98SU5408
CAS:SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.Fórmula:C18H18N2O3Pureza:99.35%Cor e Forma:SolidPeso molecular:310.35Ref: TM-T4026
1mg70,00€5mg187,00€10mg283,00€25mg518,00€50mg700,00€100mg905,00€500mg1.786,00€1mL*10mM (DMSO)207,00€Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFórmula:C21H15ClF4N4O3Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:482.82Ref: TM-T1792
5mg35,00€10mg51,00€25mg80,00€50mg96,00€100mg144,00€200mg185,00€500mg309,00€1mL*10mM (DMSO)57,00€JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Fórmula:C15H17ClN6O3Pureza:97.08%Cor e Forma:SolidPeso molecular:364.79Ref: TM-T22349
1mg38,00€5mg78,00€10mg103,00€25mg172,00€50mg250,00€100mg338,00€200mg464,00€1mL*10mM (DMSO)84,00€VEGFR-2-IN-5
CAS:VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Fórmula:C19H24N8Pureza:99.92%Cor e Forma:SolidPeso molecular:364.45Ref: TM-T2056
1mg96,00€5mg235,00€10mg350,00€25mg590,00€50mg840,00€100mg1.130,00€1mL*10mM (DMSO)235,00€BMS-794833
CAS:BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.Fórmula:C23H15ClF2N4O3Pureza:98% - 99.69%Cor e Forma:SolidPeso molecular:468.84Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Fórmula:C23H25ClFN7OPureza:99.33% - 99.86%Cor e Forma:SolidPeso molecular:469.94ZD-4190
CAS:ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.
Fórmula:C19H16BrFN6O2Pureza:99.12%Cor e Forma:SolidPeso molecular:459.27SKLB1002
CAS:SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.Fórmula:C13H12N4O2S2Pureza:98.51% - >99.99%Cor e Forma:SolidPeso molecular:320.39Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Fórmula:C22H23ClN4O7SPureza:99.03% - 99.79%Cor e Forma:SolidPeso molecular:522.96PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Cor e Forma:SolidPeso molecular:419.48OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Fórmula:C22H16F3N3O2SPureza:99.67%Cor e Forma:SolidPeso molecular:443.44Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFórmula:C21H17ClF4N4O4Pureza:99.69%Cor e Forma:SolidPeso molecular:500.83Ref: TM-T1792L
5mg35,00€10mg48,00€25mg69,00€50mg88,00€100mg140,00€200mg207,00€500mg348,00€1mL*10mM (DMSO)58,00€VEGFR2-IN-2
CAS:VEGFR2-IN-2 has anti-inflammatory and analgesic activities.Fórmula:C15H11BrN2OPureza:99.504%Cor e Forma:SolidPeso molecular:315.16Ref: TM-T9724
1mg35,00€5mg73,00€10mg105,00€25mg195,00€50mg311,00€100mg445,00€200mg617,00€1mL*10mM (DMSO)93,00€Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Fórmula:C24H21BrFN5O2Pureza:99.07% - 99.62%Cor e Forma:SolidPeso molecular:510.36Ref: TM-T8482
1mg74,00€2mg97,00€5mg165,00€10mg274,00€25mg432,00€50mg692,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)202,00€XL092
CAS:XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
Fórmula:C29H25FN4O5Pureza:98.60%Cor e Forma:SolidPeso molecular:528.53(Z)-Guggulsterone
CAS:(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Fórmula:C21H28O2Pureza:98.93% - 99.72%Cor e Forma:SolidPeso molecular:312.45Tanshinone IIA
CAS:Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.Fórmula:C19H18O3Pureza:99.04% - >99.99%Cor e Forma:Cherry CrystalPeso molecular:294.34Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Fórmula:C24H27FN6O4Pureza:99.82%Cor e Forma:SolidPeso molecular:482.51Takeda-6d
CAS:Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Fórmula:C27H19ClFN5O3SPureza:98.27%Cor e Forma:SolidPeso molecular:547.99Ref: TM-T22436
1mg92,00€2mg128,00€5mg178,00€10mg268,00€25mg439,00€50mg610,00€100mg820,00€200mg1.099,00€1mL*10mM (DMSO)243,00€Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Fórmula:C22H24BrFN4O2Pureza:99.7% - >99.99%Cor e Forma:White SolidPeso molecular:475.35Ref: TM-T1656
10mg50,00€25mg65,00€50mg92,00€100mg166,00€200mg224,00€500mg359,00€1mL*10mM (DMSO)52,00€PD173074
CAS:PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Fórmula:C28H41N7O3Pureza:98.15% - 98.21%Cor e Forma:Yellow SolidPeso molecular:523.67Ref: TM-T2642
5mg40,00€10mg54,00€25mg94,00€50mg133,00€100mg210,00€200mg371,00€500mg620,00€1mL*10mM (DMSO)56,00€TAK-593
CAS:TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Fórmula:C23H23N7O3Pureza:99.37%Cor e Forma:SolidPeso molecular:445.47Ref: TM-T16975
2mg42,00€5mg62,00€10mg96,00€25mg182,00€50mg284,00€100mg409,00€200mg575,00€1mL*10mM (DMSO)73,00€Bevacizumab
CAS:Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Pureza:95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Cor e Forma:LiquidPeso molecular:146.53 kDaRef: TM-T9904
1mg127,00€2mg202,00€5mg376,00€10mg560,00€25mg895,00€50mg1.216,00€100mg1.634,00€200mg2.213,00€Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Fórmula:C15H16O3Pureza:98.76%Cor e Forma:SolidPeso molecular:244.29PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Fórmula:C17H17N7Pureza:98.45% - 99.93%Cor e Forma:SolidPeso molecular:319.36SU4312
CAS:SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.
Fórmula:C17H16N2OPureza:>99.99%Cor e Forma:SolidPeso molecular:264.32Semaxinib
CAS:Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.
Fórmula:C15H14N2OPureza:99.84%Cor e Forma:Yellow To Yellow OrangePeso molecular:238.28ZM 306416
CAS:ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
Fórmula:C16H13ClFN3O2Pureza:99.37% - ≥95%Cor e Forma:SolidPeso molecular:333.74Vatalanib free base
CAS:Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).Fórmula:C20H15ClN4Pureza:99.52%Cor e Forma:SolidPeso molecular:346.81Sodium taurocholate
CAS:Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.Fórmula:C26H44NO7S·NaPureza:95% - 99.64%Cor e Forma:White PowderPeso molecular:537.69Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Cor e Forma:SolidPeso molecular:570.64Ref: TM-T3211
1mg51,00€5mg88,00€10mg126,00€25mg216,00€50mg328,00€100mg487,00€500mg1.093,00€1mL*10mM (DMSO)96,00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Fórmula:C23H27FN4O4Pureza:98.13%Cor e Forma:SolidPeso molecular:442.48MGCD-265 analog
CAS:Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Fórmula:C26H20FN5O2S2Pureza:98.06% - 98.68%Cor e Forma:SolidPeso molecular:517.6Ref: TM-T6351
2mg35,00€5mg52,00€10mg85,00€25mg164,00€50mg255,00€100mgA consultar1mL*10mM (DMSO)62,00€R1530
CAS:R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.Fórmula:C18H14ClFN4OPureza:98.422%Cor e Forma:SolidPeso molecular:356.78Ref: TM-TQ0317
1mg39,00€2mg52,00€5mg84,00€10mg130,00€25mg264,00€50mg423,00€100mg640,00€1mL*10mM (DMSO)93,00€SAR131675
CAS:SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Fórmula:C18H22N4O4Pureza:99.74%Cor e Forma:SolidPeso molecular:358.39Ref: TM-T6012
1mg34,00€2mg46,00€5mg70,00€10mg105,00€25mg215,00€50mg304,00€100mg427,00€200mg587,00€1mL*10mM (DMSO)79,00€Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFórmula:C31H33N5O4·C2H6O3SPureza:99.43% - 99.98%Cor e Forma:SolidPeso molecular:649.76Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Cor e Forma:SolidPeso molecular:480.54Ref: TM-T4315
1mg44,00€5mg90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€1mL*10mM (DMSO)90,00€Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFórmula:C18H22N2OPureza:98.21% - 99.87%Cor e Forma:Yellow SolidPeso molecular:282.38Telatinib
CAS:Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Fórmula:C20H16ClN5O3Pureza:97.61% - 99.81%Cor e Forma:SolidPeso molecular:409.83Altiratinib
CAS:Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,Fórmula:C26H21F3N4O4Pureza:99.67% - 99.75%Cor e Forma:SolidPeso molecular:510.46Gamabufotalin
CAS:Gamabufotalin, a Chansu bufadienolide, treats COX-2 diseases and cancer with high stability and low side effects.Fórmula:C24H34O5Pureza:99.18% - 99.51%Cor e Forma:SolidPeso molecular:402.52WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Fórmula:C16H15N3O3Pureza:99.21%Cor e Forma:SolidPeso molecular:297.31SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Fórmula:C17H16N2O3Pureza:98.91% - 99.64%Cor e Forma:Yellow-Green SolidPeso molecular:296.32
