VEGFR
Os inibidores do Receptor do Fator de Crescimento Endotelial Vascular (VEGFR) são compostos que bloqueiam a sinalização do VEGFR, um receptor chave na via VEGF, crucial para a angiogênese. Os inibidores de VEGFR impedem a formação de novos vasos sanguíneos que fornecem nutrientes e oxigênio aos tumores, inibindo assim o crescimento tumoral. Esses inibidores são amplamente utilizados na terapia contra o câncer e na pesquisa para estudar os mecanismos da angiogênese e desenvolver tratamentos anticâncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de VEGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 245 produtos de "VEGFR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFórmula:C18H22N2OPureza:98.21% - 99.87%Cor e Forma:Yellow SolidPeso molecular:282.38Telatinib
CAS:Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Fórmula:C20H16ClN5O3Pureza:97.61% - 99.81%Cor e Forma:SolidPeso molecular:409.83Altiratinib
CAS:Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,Fórmula:C26H21F3N4O4Pureza:99.67% - 99.75%Cor e Forma:SolidPeso molecular:510.46SU5408
CAS:SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.Fórmula:C18H18N2O3Pureza:99.35%Cor e Forma:SolidPeso molecular:310.35Ref: TM-T4026
1mg70,00€5mg187,00€10mg283,00€25mg518,00€50mg700,00€100mg905,00€500mg1.786,00€1mL*10mM (DMSO)207,00€Gamabufotalin
CAS:Gamabufotalin, a Chansu bufadienolide, treats COX-2 diseases and cancer with high stability and low side effects.Fórmula:C24H34O5Pureza:99.18% - 99.51%Cor e Forma:SolidPeso molecular:402.52WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Fórmula:C16H15N3O3Pureza:99.21%Cor e Forma:SolidPeso molecular:297.31SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Fórmula:C17H16N2O3Pureza:98.91% - 99.64%Cor e Forma:Yellow-Green SolidPeso molecular:296.32SKLB 610
CAS:SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively,
Fórmula:C21H16F3N3O3Pureza:99.33% - 99.83%Cor e Forma:SolidPeso molecular:415.37SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFórmula:C17H15NO2Pureza:99.46%Cor e Forma:SolidPeso molecular:265.31Tivozanib
CAS:Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Fórmula:C22H19ClN4O5Pureza:98.08% - 99.67%Cor e Forma:SolidPeso molecular:454.86Ref: TM-T2456
2mg38,00€5mg57,00€10mg79,00€25mg135,00€50mg226,00€100mg405,00€200mg597,00€1mL*10mM (DMSO)63,00€MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Fórmula:C21H18N2OPureza:98.53%Cor e Forma:SolidPeso molecular:314.38AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Fórmula:C24H25N5O4Pureza:97.71% - 98.37%Cor e Forma:SolidPeso molecular:447.49AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Fórmula:C29H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:535.56Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Fórmula:C15H18O3Pureza:98.48% - 99.96%Cor e Forma:SolidPeso molecular:246.3Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Fórmula:C24H27FN6O4Pureza:99.54% - 99.77%Cor e Forma:SolidPeso molecular:482.51Ref: TM-T7104
5mg51,00€10mg79,00€25mg129,00€50mg213,00€100mg358,00€200mg535,00€500mg843,00€1mL*10mM (DMSO)57,00€AAL-993
CAS:AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.Fórmula:C20H16F3N3OPureza:99.65%Cor e Forma:SolidPeso molecular:371.36Ref: TM-T21593
1mg43,00€5mg93,00€10mg138,00€25mg260,00€50mg409,00€100mg605,00€500mg1.288,00€1mL*10mM (DMSO)92,00€RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Fórmula:C24H16F6N6OPureza:99.56%Cor e Forma:SolidPeso molecular:518.41Ref: TM-T6296
1mg44,00€2mg59,00€5mg93,00€10mg140,00€25mg253,00€50mg413,00€100mg605,00€1mL*10mM (DMSO)94,00€NVP-BAW2881
CAS:NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and acute skin inflammation.Fórmula:C22H15F3N4O2Pureza:98.19% - 99.97%Cor e Forma:SolidPeso molecular:424.38Ref: TM-T3641
1mg34,00€2mg48,00€5mg71,00€10mg109,00€25mg200,00€50mg324,00€100mg470,00€500mg1.054,00€1mL*10mM (DMSO)69,00€SU5205
CAS:SU5205 is a VEGFR2 inhibitor.
Fórmula:C15H10FNOPureza:99.62% - 99.67%Cor e Forma:SolidPeso molecular:239.24Foretinib
CAS:Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.Fórmula:C34H34F2N4O6Pureza:98.07% - 99.68%Cor e Forma:SolidPeso molecular:632.65Ref: TM-T3113
2mg39,00€5mg57,00€10mg79,00€25mg133,00€50mg207,00€100mg354,00€500mg848,00€1mL*10mM (DMSO)79,00€Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Fórmula:C23H26FN5O3Pureza:97.35%Cor e Forma:SolidPeso molecular:439.48Ref: TM-T8491
1mg101,00€2mg142,00€5mg215,00€10mg340,00€25mg583,00€50mg842,00€100mg1.144,00€200mg1.521,00€1mL*10mM (DMSO)236,00€Fruquintinib
CAS:Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-Fórmula:C21H19N3O5Pureza:98.84% - 99.89%Cor e Forma:SolidPeso molecular:393.39Ref: TM-T2656
2mg35,00€5mg52,00€10mg85,00€25mg117,00€50mg147,00€100mg250,00€500mg620,00€1mL*10mM (DMSO)58,00€Orantinib
CAS:Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.Fórmula:C18H18N2O3Pureza:98.92% - 99.52%Cor e Forma:SolidPeso molecular:310.35AG-13958
CAS:AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.Fórmula:C26H22FN7OPureza:99.4%Cor e Forma:SolidPeso molecular:467.5Ref: TM-T7493
1mg92,00€5mg250,00€10mg385,00€25mg620,00€50mg893,00€100mg1.189,00€1mL*10mM (DMSO)260,00€Motesanib
CAS:Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.Fórmula:C22H23N5OPureza:98% - 99.09%Cor e Forma:SolidPeso molecular:373.45Ref: TM-T2288
5mg34,00€10mg49,00€25mg81,00€50mg114,00€100mg160,00€200mg230,00€500mg389,00€1mL*10mM (DMSO)39,00€KRN-633
CAS:KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.Fórmula:C20H21ClN4O4Pureza:99.53% - 99.73%Cor e Forma:SolidPeso molecular:416.86JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Fórmula:C22H20BrN5O2Pureza:99.41% - 99.97%Cor e Forma:SolidPeso molecular:466.33Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Fórmula:C25H21FN6O2SPureza:96.17% - 97.49%Cor e Forma:SolidPeso molecular:488.54Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Fórmula:C25H27FN4O3Pureza:97.21% - 99.94%Cor e Forma:SolidPeso molecular:450.51Ref: TM-T2500
2mg42,00€5mg63,00€10mg92,00€25mg136,00€50mg177,00€100mg254,00€200mg462,00€500mg742,00€1mL*10mM (DMSO)69,00€SCR-1481B1
CAS:SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFórmula:C32H40ClF2N6O13PPureza:98.07%Cor e Forma:SolidPeso molecular:821.12Ref: TM-T5349
1mg35,00€2mg50,00€5mg74,00€10mg113,00€25mg200,00€50mg333,00€100mg495,00€1mL*10mM (DMSO)102,00€Oglufanide
CAS:Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).Fórmula:C16H19N3O5Pureza:99.80%Cor e Forma:SolidPeso molecular:333.34EOC317
CAS:EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).Fórmula:C27H26F5N7O3Pureza:98.00% - 99.26%Cor e Forma:SolidPeso molecular:591.53SU5208
CAS:SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).Fórmula:C13H9NOSPureza:99.62%Cor e Forma:SolidPeso molecular:227.28Ref: TM-T22432
1mg46,00€5mg94,00€10mg148,00€25mg225,00€50mg310,00€100mg434,00€200mg583,00€1mL*10mM (DMSO)95,00€Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFórmula:C21H18FN5OPureza:98% - 98.24%Cor e Forma:SolidPeso molecular:375.4Ref: TM-T2514
5mg48,00€10mg80,00€25mg119,00€50mg178,00€100mg259,00€200mg477,00€500mg772,00€1mL*10mM (DMSO)50,00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Fórmula:C21H23N7O2S·HClPureza:99.87%Cor e Forma:SolidPeso molecular:473.98Ref: TM-T6930
10mg44,00€25mg70,00€50mg96,00€100mg140,00€200mg229,00€500mg329,00€1mL*10mM (DMSO)34,00€KI8751
CAS:KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Fórmula:C24H18F3N3O4Pureza:99.22% - 99.9%Cor e Forma:SolidPeso molecular:469.41Ref: TM-T2446
2mg37,00€5mg52,00€10mg86,00€25mg156,00€50mg294,00€100mg472,00€200mg670,00€1mL*10mM (DMSO)56,00€Vatalanib dihydrochloride
CAS:Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.Fórmula:C20H15ClN4·2HClPureza:99.16%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:419.73Golvatinib
CAS:Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factorFórmula:C33H37F2N7O4Pureza:98.24% - ≥95%Cor e Forma:SolidPeso molecular:633.69Ref: TM-T6517
1mgA consultar2mg46,00€5mg66,00€10mg92,00€25mg149,00€50mg197,00€100mg350,00€1mL*10mM (DMSO)A consultarNingetinib Tosylate
CAS:Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Fórmula:C38H37FN4O8SPureza:99.93%Cor e Forma:SolidPeso molecular:728.79Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFórmula:C29H27F3N6OPureza:98% - 99.60%Cor e Forma:SolidPeso molecular:532.56SU5214
CAS:SU5214 is a modulator of tyrosine kinase signal transduction.Fórmula:C16H13NO2Pureza:99.45% - 99.55%Cor e Forma:SolidPeso molecular:251.28UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Fórmula:C19H25ClN8Pureza:99.52%Cor e Forma:SolidPeso molecular:400.91Ref: TM-T2056L
1mg84,00€5mg168,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€1mL*10mM (DMSO)185,00€Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Fórmula:C22H28FN4O6PPureza:98.56%Cor e Forma:SolidPeso molecular:494.45Ramucirumab
CAS:Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
Fórmula:C285H434N74O88S2Pureza:98.2% (SDS-PAGE); 99.2% (SEC-HPLC) - 99.20%Cor e Forma:LiquidPeso molecular:143.77 kDaNingetinib
CAS:Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Fórmula:C31H29FN4O5Pureza:99.95% - 99.98%Cor e Forma:SolidPeso molecular:556.58Orobol
CAS:Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.Fórmula:C15H10O6Pureza:98% - 98%Cor e Forma:SolidPeso molecular:286.24XL 999
CAS:Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）Fórmula:C26H28FN5OPureza:98.24% - 99.55%Cor e Forma:SolidPeso molecular:445.53Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Fórmula:C28H24FN3O5Pureza:99.68% - 99.88%Cor e Forma:SolidPeso molecular:501.51BFH772
CAS:BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).Fórmula:C23H16F3N3O3Pureza:97.71% - 99.89%Cor e Forma:SolidPeso molecular:439.39Su1498
CAS:Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the VEGF receptor 2, having negligible activity at several other serine/threonine and tyrosine kinases.
Fórmula:C25H30N2O2Pureza:99.54%Cor e Forma:SolidPeso molecular:390.52
