VEGFR
Os inibidores do Receptor do Fator de Crescimento Endotelial Vascular (VEGFR) são compostos que bloqueiam a sinalização do VEGFR, um receptor chave na via VEGF, crucial para a angiogênese. Os inibidores de VEGFR impedem a formação de novos vasos sanguíneos que fornecem nutrientes e oxigênio aos tumores, inibindo assim o crescimento tumoral. Esses inibidores são amplamente utilizados na terapia contra o câncer e na pesquisa para estudar os mecanismos da angiogênese e desenvolver tratamentos anticâncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de VEGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 245 produtos de "VEGFR"
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Acrizanib
CAS:Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2.Fórmula:C20H18F3N7O2Pureza:98.71% - 99.64%Cor e Forma:SolidPeso molecular:445.4Ref: TM-T5373
1mg111,00€5mg274,00€10mg424,00€25mg723,00€50mg1.008,00€100mg1.311,00€1mL*10mM (DMSO)303,00€Arginyl-Glutamine
CAS:Arginyl-Glutamine (Arg-Gln) is a dipeptide nutritional supplement that protects neonatal mice from hyperoxia-induced lung injury, lowering VEGF levels.Fórmula:C11H22N6O4Pureza:95.2%Cor e Forma:SolidPeso molecular:302.33VEGFR-2-IN-32
VEGFR-2-IN-32 (Comp 3a) is an inhibitor of VEGFR-2, exhibiting an inhibitory concentration (IC 50) of 8.93 nM, and demonstrates cytotoxic activity towards PC-3Fórmula:C15H12N4OPureza:98%Cor e Forma:SolidPeso molecular:264.285Z-7-Oxozeaenol
CAS:5Z-7-Oxozeaenol: TGF-β-activated kinase 1 inhibitor, IC50 8.1 nM; VEGF-R2 inhibitor, IC50 52 nM; weak MEK1 inhibitor, IC50 411 nM.Fórmula:C19H22O7Pureza:99%Cor e Forma:SolidPeso molecular:362.37Tyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedCor e Forma:Odour SolidRef: TM-L2200
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarKinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Cor e Forma:Odour SolidRef: TM-L1600
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarAngiogenesis related Compound Library
A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and highCor e Forma:Odour SolidRef: TM-L4800
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarFDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
Cor e Forma:LiquidVEGF-IN-1
VEGF-IN-1 (compound 6) reduces the release of VEGF in U87-MG cells and inhibits angiogenesis in vitro. Additionally, it suppresses cell proliferation by inducing autophagy in tumor cells, with an IC50 value of 28.35 μM against U87-MG cells.Fórmula:C27H22Cl2N4RuCor e Forma:SolidPeso molecular:574.47VEGFR-2-IN-55
VEGFR-2-IN-55 (Compound 30) is an effective VEGFR-2 kinase inhibitor with an IC50 of 1.24 nM and exhibits anti-tumor activity.Cor e Forma:Odour SolidTovecimig
Tovecimig is a G1-scFvlh_L-κ type bispecific antibody targeting VEGFA/DLL4.Cor e Forma:Odour LiquidVEGFR-2-IN-29
CAS:VEGFR-2-IN-29 is a VEGFR2 inhibitor.Fórmula:C16H11N3O3Pureza:99.59%Cor e Forma:SolidPeso molecular:293.28Sozinibercept
CAS:Sozinibercept (OPT 302; VGX-300), a VEGFR-3 inhibitor, blocks VEGF-C/D to curb angiogenesis and vascular leakage, and treats rat diabetic retinal edema.Cor e Forma:LiquidPulocimab
CAS:Pulocimab, an anti-VEGFR2 monoclonal antibody (mAb), is utilized in cancer research [1].Cor e Forma:LiquidVEGFR-2-IN-59
VEGFR-2-IN-59 (Compound 3h) is an inhibitor of VEGFR2 with an IC50 of 3.73 µM. It exhibits cytotoxicity in cancer cell lines A549, HT-29, A375, MCF7, and NHDF, with IC50 values of 20.91, 19.70, 9.63, 17.43, and 20.71 μM, respectively. VEGFR-2-IN-59 also inhibits tubular structure formation and demonstrates anti-angiogenic properties.Fórmula:C19H20N6O4Cor e Forma:SolidPeso molecular:396.4KLTWQELYQLKYKGI
CAS:KLTWQELYQLKYKGI (QK) is a VEGF-mimicking peptide that competes with VEGF by binding to its receptors.Fórmula:C92H143N21O23Pureza:98%Cor e Forma:SolidPeso molecular:1911.25GNQWFI
CAS:GNQWFI, an anti-Flt1 peptide, functions as a VEGFR1-specific antagonist. It inhibits interactions between VEGFR1 and various ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF), and suppresses VEGF-induced endothelial cell migration and tubulogenesis. GNQWFI holds potential for research in cancer, asthma, and other ocular diseases.Fórmula:C37H49N9O9Cor e Forma:SolidPeso molecular:763.84T-1-MCPAB
T-1-MCPAB, a VEGFR-2 inhibitor with an IC50 of 0.135 µM, effectively suppresses MCF7 cell migration and has applications in cancer research [1].Pureza:98%Cor e Forma:Odour SolidRanibizumab
CAS:Ranibizumab is a humanized monoclonal antibody fragment designed to target and inhibit vascular endothelial growth factor (VEGF), including VEGF110, VEGF121,Pureza:98%Cor e Forma:LiquidPeso molecular:149.19KDProtein LMWP
CAS:Protein LMWP, a cell-penetrating peptide, exhibits inhibitory activity against vascular endothelial growth factor (VEGF), and is utilized in cancer research forFórmula:C72H142N44O16Pureza:98%Cor e Forma:SolidPeso molecular:1880.18
