CSF-1R
Os inibidores de CSF-1R são compostos que visam e inibem o receptor do Fator Estimulante de Colônias 1 (CSF-1R), uma tirosina quinase receptora envolvida na regulação de macrófagos e outras células imunológicas. A inibição de CSF-1R tem potencial terapêutico em doenças caracterizadas por atividade excessiva de macrófagos, como câncer, inflamação e distúrbios autoimunes. Na CymitQuimica, oferecemos inibidores de CSF-1R para apoiar sua pesquisa em imunologia, oncologia e inflamação.
Foram encontrados 42 produtos de "CSF-1R"
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Edicotinib
CAS:Edicotinib (JNJ-527) is a blood-brain permeable, selective CSF-1R inhibitor, with lesser inhibitory effects on KIT and FLT3.Cost-effective and quality-assured.
Fórmula:C27H35N5O2Pureza:98.58% - 99.72%Cor e Forma:SolidPeso molecular:461.6CSF1R-IN-2
CAS:CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Fórmula:C20H20FN7O2Pureza:99.29%Cor e Forma:SolidPeso molecular:409.42CSF1R-IN-1
CAS:CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Fórmula:C25H20F3N5O2Pureza:97.02% - 98.56%Cor e Forma:SolidPeso molecular:479.45Ref: TM-T10894
1mg88,00€5mg200,00€10mg309,00€25mg522,00€50mg747,00€100mg1.035,00€200mg1.378,00€1mL*10mM (DMSO)219,00€Anti-CSF1R Antibody (8O797)
Anti-CSF1R Antibody (8O797) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (8O797) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CSF1R Antibody (4Y587)
Anti-CSF1R Antibody (4Y587) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (4Y587) can be used in FCM.Cor e Forma:Odour LiquidPLX647
CAS:PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Fórmula:C21H17F3N4Pureza:99.38%Cor e Forma:SolidPeso molecular:382.38Ref: TM-T1925
2mg39,00€5mg57,00€10mg86,00€25mg127,00€50mg178,00€100mg264,00€200mg389,00€1mL*10mM (DMSO)60,00€CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:83.04 kDa (predicted); 110.87 kDa (reducing conditions)CSF1R Protein, Human, Recombinant (mFc)
CSF1R Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.Cor e Forma:Lyophilized PowderPeso molecular:81.5 kDa (predicted)Ref: TM-TMPY-05264
1mg2.099,00€5µg47,00€10µg65,00€20µg94,00€50µg167,00€100µg334,00€200µg499,00€500µg1.046,00€CSF1R Protein, Human, Recombinant (His & GST)
CSF1R Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.Cor e Forma:Lyophilized PowderPeso molecular:76 kDa (predicted); 75 kDa (reducing conditions)CSF1R Protein, Cynomolgus, Recombinant (hFc)
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCFCor e Forma:Lyophilized PowderPeso molecular:105-130 KDa (reducing condition)Ref: TM-TMPJ-01418
1mg2.071,00€5µg77,00€10µg111,00€20µg171,00€50µg303,00€100µg479,00€200µg786,00€500µg1.506,00€CSF1R Protein, Mouse, Recombinant (hFc)
CSF1R Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:81.9 kDa (predicted)Ref: TM-TMPY-05436
1mg4.207,00€5µg77,00€10µg109,00€20µg174,00€50µg350,00€100µg668,00€200µg1.017,00€500µg2.071,00€CSF1R Protein, Human, Recombinant
CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1.Cor e Forma:Lyophilized PowderPeso molecular:55.1 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation)CSF1R Protein, Human, Recombinant (hFc)
CSF1R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:81.2 kDa (predicted)Ref: TM-TMPY-05429
1mg2.931,00€5µg57,00€10µg90,00€20µg126,00€50µg244,00€100µg472,00€200µg691,00€500µg1.488,00€CSF1R Protein, Mouse, Recombinant (His)
CSF1R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:56.8 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-01833
1mg3.037,00€5µg67,00€10µg95,00€20µg153,00€50µg290,00€100µg486,00€200µg837,00€500µg1.718,00€CSF1R Protein, Mouse, Recombinant (His), Biotinylated
CSF1R Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:56.8 kDa (predicted)CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:SDS-PAGE: 97.7%; SEC-HPLC: 99.7%Cor e Forma:Lyophilized PowderPeso molecular:56 kDa (predicted); 85-95 kDa (reducing condition, due to glycosylation)CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)
CSF1R Protein (Ala299-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:25.3 kDa (predicted)CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:31.1 kDa (predicted)CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:57.76 kDa (predicted); 82.52 kDa (reducing conditions)CSF1R Protein, Cynomolgus, Recombinant (His)
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCFCor e Forma:Lyophilized PowderPeso molecular:80-120 KDa (reducing condition)Ref: TM-TMPJ-01419
1mg2.535,00€5µg90,00€10µg130,00€20µg193,00€50µg381,00€100µg600,00€200µg947,00€500µg1.765,00€Anti-CSF1R Antibody (5C535)
Anti-CSF1R Antibody (5C535) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (5C535) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CSF1R Antibody (1R707)
Anti-CSF1R Antibody (1R707) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (1R707) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CSF1R Antibody (2I506)
Anti-CSF1R Antibody (2I506) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (2I506) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CSF1R Antibody-FITC (4Y587)
Anti-CSF1R Antibody-FITC (4Y587) is a FITC-conjugated Mouse antibody targeting CSF1R. Anti-CSF1R Antibody-FITC (4Y587) can be used in FCM.Cor e Forma:Odour LiquidAnti-CSF1R Antibody (7V18)
Anti-CSF1R Antibody (7V18) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (7V18) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CSF1R Antibody (5B661)
Anti-CSF1R Antibody (5B661) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (5B661) can be used in ELISA,ELISA(Cap).Cor e Forma:Odour LiquidPLX5622
CAS:PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.Fórmula:C21H19F2N5OPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:395.41Ref: TM-T7100
1mg43,00€5mg81,00€10mg118,00€25mg230,00€50mg385,00€100mg502,00€200mg710,00€1mL*10mM (DMSO)77,00€Sotuletinib
CAS:Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.Fórmula:C20H22N4O3SPureza:97.43% - 99.82%Cor e Forma:SolidPeso molecular:398.48Ref: TM-T6119
1mg37,00€5mg79,00€10mg111,00€25mg172,00€50mg216,00€100mg378,00€500mg868,00€1mL*10mM (DMSO)87,00€Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Cor e Forma:SolidPeso molecular:480.54Ref: TM-T4315
1mg44,00€5mg90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€1mL*10mM (DMSO)90,00€cFMS Receptor Inhibitor II
CAS:cFMS Receptor Inhibitor II is a CSF1R kinase inhibitorFórmula:C23H20N4OPureza:99.8%Cor e Forma:SolidPeso molecular:368.43Ref: TM-T5586
1mg49,00€2mg65,00€5mg97,00€10mg154,00€25mg255,00€50mg376,00€100mg547,00€1mL*10mM (DMSO)106,00€AZD7507
CAS:AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Fórmula:C23H27FN6O3Pureza:99.55% - 99.78%Cor e Forma:SolidPeso molecular:454.5Ref: TM-T14380
1mg50,00€5mg110,00€10mg161,00€25mg289,00€50mg419,00€100mg583,00€200mg787,00€1mL*10mM (DMSO)127,00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Cor e Forma:SolidPeso molecular:419.48GW2580
CAS:GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Fórmula:C20H22N4O3Pureza:99.48% - >99.99%Cor e Forma:SolidPeso molecular:366.41OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Fórmula:C22H16F3N3O2SPureza:99.67%Cor e Forma:SolidPeso molecular:443.44Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Fórmula:C21H21FN6OPureza:99.35% - 99.92%Cor e Forma:SolidPeso molecular:392.43Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFórmula:C21H18FN5OPureza:98% - 98.24%Cor e Forma:SolidPeso molecular:375.4Ref: TM-T2514
5mg48,00€10mg80,00€25mg119,00€50mg178,00€100mg259,00€200mg477,00€500mg772,00€1mL*10mM (DMSO)50,00€Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFórmula:C20H15ClF3N5Pureza:98.34% - 99.45%Cor e Forma:SolidPeso molecular:417.81Ref: TM-T2115
5mg46,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€1mL*10mM (DMSO)49,00€PRN1371
CAS:PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Fórmula:C26H30Cl2N6O4Pureza:98.65%Cor e Forma:SolidPeso molecular:561.46Ref: TM-TQ0015
1mg77,00€2mg100,00€5mg166,00€10mg289,00€25mg492,00€50mg710,00€100mg973,00€1mL*10mM (DMSO)200,00€Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Fórmula:C23H25N7O2Pureza:99.05% - 99.57%Cor e Forma:SolidPeso molecular:431.49Ref: TM-T10652
1mg87,00€5mg178,00€10mg295,00€25mg505,00€50mg690,00€100mg888,00€1mL*10mM (DMSO)203,00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Fórmula:C21H23N7O2S·HClPureza:99.87%Cor e Forma:SolidPeso molecular:473.98CSF1R Protein, Feline, Recombinant (His & SUMO)
CSF1R Protein, Feline, Recombinant (His & SUMO) is expressed in E.Cor e Forma:Lyophilized PowderPeso molecular:70.8 kDa (predicted)Ref: TM-TMPH-00354
1mg2.277,00€5µg120,00€10µg195,00€20µg324,00€50µg489,00€100µg670,00€200µg964,00€500µg1.558,00€Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.
Fórmula:C27H21N3O3Pureza:99.22%Cor e Forma:SolidPeso molecular:435.47
