PDGFR
Os inibidores do receptor do fator de crescimento derivado de plaquetas (PDGFR) são compostos que bloqueiam a sinalização do PDGFR, um receptor envolvido no crescimento celular, proliferação e angiogênese. O PDGFR desempenha um papel significativo no desenvolvimento dos vasos sanguíneos que alimentam os tumores. Inibir o PDGFR pode, portanto, impedir a angiogênese, tornando esses inibidores valiosos na terapia contra o câncer. Na CymitQuimica, oferecemos uma seleção de inibidores de PDGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 126 produtos de "PDGFR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Lenvatinib
CAS:<p>Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.</p>Fórmula:C21H19ClN4O4Pureza:98.46% - 99.69%Cor e Forma:SolidPeso molecular:426.852-(3,4-Dimethoxyphenylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS:Fórmula:C18H20N2O4SPureza:95%Cor e Forma:SolidPeso molecular:360.4274Trapidil
CAS:<p>Trapidil (Avantrin) is a coronary vasodilator agent.</p>Fórmula:C10H15N5Pureza:99.42%Cor e Forma:SolidPeso molecular:205.26CT52923
CAS:<p>CT52923: selective oral PDGFR blocker, ATP-inhibitor, used in research for various diseases including cancer.</p>Fórmula:C23H25N5O4SPureza:99.926%Cor e Forma:SoildPeso molecular:467.54KG5
CAS:<p>KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).</p>Fórmula:C20H16F3N7OSPureza:98.32%Cor e Forma:SolidPeso molecular:459.45IMC-2C5
<p>IMC-2C5 is a humanized monoclonal antibody targeting PDGFRB/CD140b.</p>Pureza:>95%Cor e Forma:Odour LiquidKN1022
CAS:<p>KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.</p>Fórmula:C21H22N6O5Pureza:99.68%Cor e Forma:SoildPeso molecular:438.44Rinucumab
CAS:<p>Rinucumab (REGN 2176) is an anti-PDGF IgG4-like monoclonal antibody that can be used to study age-related macular degeneration.</p>Pureza:99.2% (SDS-PAGE); 97.7% (SEC-HPLC) - 99.2% (SDS-PAGE); 97.7% (SEC-HPLC)Cor e Forma:LiquidTyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Cor e Forma:Odour SolidKIT/PDGFRA-IN-1
<p>KIT/PDGFRA-IN-1 (compound 19) is an inhibitor targeting the stem cell growth factor receptor (KIT) and platelet-derived growth factor receptor alpha (PDGFRA). Its IC50 values are 2.3 µM for KIT-wt, 12 µM for KIT-D816H, 492 µM for KIT-T670I, 0.8 µM for PDGFRA-wt, 99.9 µM for PDGFRA-D842V, 42.3 µM for PDGFRA-T674I, and 4.3 µM for PDGFRA-G680R. The GR50 values for GIST-T1, T1-a-D842V, and GIST-48B cell lines (gastrointestinal stromal tumor cell lines with PDGFR and KIT mutations) are 12 nM, 8900 nM, and ≥10,000 nM, respectively.</p>Fórmula:C26H18F3N5O2Cor e Forma:SolidPeso molecular:489.449Tyrphostin RG 13022
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Cor e Forma:White to Yellow to Green powder to crystalPeso molecular:266.30Anti-PDGFRB Antibody (4H405)
<p>Anti-PDGFRB Antibody (4H405) is a Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody (4H405) can be used in ELISA(Det).</p>Cor e Forma:Odour LiquidRegorafenib
CAS:Fórmula:C21H15ClF4N4O3Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:482.82Anti-PDGFRB Antibody-FITC (1A610)
<p>Anti-PDGFRB Antibody-FITC (1A610) is a FITC-conjugated Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody-FITC (1A610) can be used in FCM.</p>Cor e Forma:Odour LiquidTyrphostin A9
CAS:Fórmula:C18H22N2OPureza:>98.0%(GC)Cor e Forma:Light orange to Yellow to Green powder to crystalPeso molecular:282.39Anti-PDGFRB Antibody-PE (7C914)
<p>Anti-PDGFRB Antibody-PE (7C914) is a PE-conjugated Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody-PE (7C914) can be used in FCM.</p>Cor e Forma:Odour LiquidAnti-PDGFRB Antibody (4V910)
<p>Anti-PDGFRB Antibody (4V910) is a Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody (4V910) can be used in ELISA.</p>Cor e Forma:Odour LiquidAnti-PDGFRB Antibody (7C914)
<p>Anti-PDGFRB Antibody (7C914) is a Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody (7C914) can be used in FCM.</p>Cor e Forma:Odour LiquidAnti-Phospho-PDGFRB (Tyr740) Antibody (9D509)
<p>Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) is an antibody targeting Phospho-PDGFRB (Tyr740). Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) can be used in ELISA, WB.</p>Cor e Forma:Odour Liquid
