PDGFR
Os inibidores do receptor do fator de crescimento derivado de plaquetas (PDGFR) são compostos que bloqueiam a sinalização do PDGFR, um receptor envolvido no crescimento celular, proliferação e angiogênese. O PDGFR desempenha um papel significativo no desenvolvimento dos vasos sanguíneos que alimentam os tumores. Inibir o PDGFR pode, portanto, impedir a angiogênese, tornando esses inibidores valiosos na terapia contra o câncer. Na CymitQuimica, oferecemos uma seleção de inibidores de PDGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 131 produtos para "PDGFR".
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Regorafénib N-oxyde (M2)
CAS:Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.Fórmula:C21H15ClF4N4O4Pureza:98.03% - 98.26%Cor e Forma:White SolidPeso molecular:498.816,7-Dimethoxy-2-phenylquinoxaline
CAS:Fórmula:C16H14N2O2Pureza:98%Cor e Forma:SolidPeso molecular:266.2946AG 1295
CAS:AG 1295 is a selective PDGFR tyrosine-kinase inhibitor; it blocks PDGFR autophosphorylation without affecting EGF receptor.Fórmula:C16H14N2Pureza:99.93%Cor e Forma:SolidPeso molecular:234.3Axitinib
CAS:Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Fórmula:C22H18N4OSPureza:98.9% - 99.74%Cor e Forma:Off-White SolidPeso molecular:386.472-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Fórmula:C21H15ClF4N4O3Pureza:98%Cor e Forma:SolidPeso molecular:482.8154Ref: IN-DA00ICN3
100gA consultar10mg28,00€50mg43,00€100mg52,00€250mg65,00€500mg94,00€1g124,00€5g283,00€10g583,00€50g615,00€Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Fórmula:C21H19ClN4O4Pureza:98.46% - 99.96%Cor e Forma:White SolidPeso molecular:426.85N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Fórmula:C28H29N7OPureza:98.60%Cor e Forma:SolidPeso molecular:479.576Ref: TM-T11641
1mg87,00€5mg166,00€1mL*10mM (DMSO)170,00€10mg303,00€25mg512,00€50mg737,00€100mg1.018,00€3-(3,4-Dimethoxyphenyl)-2-(pyridin-3-yl)acrylonitrile
CAS:Fórmula:C16H14N2O2Pureza:98%Cor e Forma:SolidPeso molecular:266.2946Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Cor e Forma:SolidPeso molecular:437.518Sunitinib Malate
CAS:Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.Fórmula:C26H33FN4O7Pureza:98% - 99.26%Cor e Forma:SolidPeso molecular:532.56CT52923
CAS:CT52923: selective oral PDGFR blocker, ATP-inhibitor, used in research for various diseases including cancer.Fórmula:C23H25N5O4SPureza:99.92%Cor e Forma:SolidPeso molecular:467.54(Z)-SU14813
CAS:(Z)-SU14813 is a tyrosine kinase inhibitor with anticardiogenic and antitumor activity.Fórmula:C23H27FN4O4Pureza:98.96%Cor e Forma:Yellow SolidPeso molecular:442.48KG5
CAS:KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).Fórmula:C20H16F3N7OSPureza:98.32%Cor e Forma:SolidPeso molecular:459.45Ref: TM-T41003
1mg33,00€2mg44,00€5mg71,00€1mL*10mM (DMSO)85,00€10mg100,00€25mg193,00€50mg296,00€100mg425,00€200mg595,00€IMC-2C5
IMC-2C5 is a humanized monoclonal antibody targeting PDGFRB/CD140b.Pureza:>95%Cor e Forma:LiquidPeso molecular:145.06 kDaKN1022
CAS:KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.Fórmula:C21H22N6O5Pureza:99.68%Cor e Forma:SolidPeso molecular:438.44Rinucumab
CAS:Rinucumab (REGN 2176) is an anti-PDGF IgG4-like monoclonal antibody that can be used to study age-related macular degeneration.Pureza:99.2% (SDS-PAGE); 97.7% (SEC-HPLC) - 99.2% (SDS-PAGE); 97.7% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.58 kDaTyrosine Kinase Inhibitor Library
A unique collection of xnum HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;Cor e Forma:Odour SolidRef: TM-L2200
1mgA consultar10μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar
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