PDGFR
Os inibidores do receptor do fator de crescimento derivado de plaquetas (PDGFR) são compostos que bloqueiam a sinalização do PDGFR, um receptor envolvido no crescimento celular, proliferação e angiogênese. O PDGFR desempenha um papel significativo no desenvolvimento dos vasos sanguíneos que alimentam os tumores. Inibir o PDGFR pode, portanto, impedir a angiogênese, tornando esses inibidores valiosos na terapia contra o câncer. Na CymitQuimica, oferecemos uma seleção de inibidores de PDGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 131 produtos para "PDGFR".
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Anti-PDGFRB Antibody (8J167)
Anti-PDGFRB Antibody (8J167) is an antibody targeting PDGFRB. Anti-PDGFRB Antibody (8J167) can be used in ELISA, IHC.Cor e Forma:Odour LiquidON123300
CAS:ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Fórmula:C24H27N7OPureza:99.53% - 99.7%Cor e Forma:SolidPeso molecular:429.52Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFórmula:C21H15ClF4N4O3Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:482.82Ref: TM-T1792
5mg34,00€1mL*10mM (DMSO)35,00€10mg49,00€25mg75,00€50mg90,00€100mg137,00€200mg175,00€500mg294,00€PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Cor e Forma:SolidPeso molecular:369.22Ref: TM-T6932
1mg37,00€2mg50,00€1mL*10mM (DMSO)52,00€5mg63,00€10mg94,00€25mg146,00€50mg210,00€100mg294,00€Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Fórmula:C22H23ClN4O7SPureza:99.03% - 99.79%Cor e Forma:SolidPeso molecular:522.96Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFórmula:C21H17ClF4N4O4Pureza:99.69%Cor e Forma:SolidPeso molecular:500.83Ref: TM-T1792L
5mg34,00€1mL*10mM (DMSO)37,00€10mg46,00€25mg65,00€50mg94,00€100mg133,00€200mg197,00€500mg329,00€Methylnissolin
CAS:Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.Fórmula:C17H16O5Pureza:99.68% - 99.98%Cor e Forma:SolidPeso molecular:300.31Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Fórmula:C16H14N2O2Pureza:99.94% - >99.99%Cor e Forma:SolidPeso molecular:266.29Ref: TM-T6711
2mg38,00€5mg55,00€1mL*10mM (DMSO)77,00€10mg95,00€25mg172,00€50mg264,00€100mg389,00€200mg555,00€Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Fórmula:C25H27FN4O3Pureza:97.21% - 99.94%Cor e Forma:SolidPeso molecular:450.51Ref: TM-T2500
2mg39,00€5mg59,00€1mL*10mM (DMSO)65,00€10mg87,00€25mg129,00€50mg168,00€100mg240,00€200mg439,00€500mg703,00€Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Fórmula:C24H27FN6O4Pureza:99.82%Cor e Forma:Black SolidPeso molecular:482.51Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Fórmula:C23H21N5O3SPureza:99.38% - >99.99%Cor e Forma:SolidPeso molecular:447.51TAK-593
CAS:TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Fórmula:C23H23N7O3Pureza:99.37%Cor e Forma:SolidPeso molecular:445.47Ref: TM-T16975
2mg42,00€5mg62,00€1mL*10mM (DMSO)73,00€10mg96,00€25mg182,00€50mg284,00€100mg409,00€200mg575,00€Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Fórmula:C29H34N6O4S2Pureza:97.67% - 98.44%Cor e Forma:SolidPeso molecular:594.75PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Fórmula:C17H17N7Pureza:98.45% - 99.93%Cor e Forma:SolidPeso molecular:319.36SU4312
CAS:SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.Fórmula:C17H16N2OPureza:>99.99%Cor e Forma:SolidPeso molecular:264.32N-(p-Coumaroyl) serotonin
CAS:N-(p-Coumaroyl) Serotonin, from safflower seeds, has antioxidant, antitumor properties and improves vascular health.Fórmula:C19H18N2O3Pureza:98.10% - 98.89%Cor e Forma:SolidPeso molecular:322.36Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Fórmula:C22H28FN4O6PPureza:98.56%Cor e Forma:SolidPeso molecular:494.45Crenolanib
CAS:Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).Fórmula:C26H29N5O2Pureza:98.40% - 99.98%Cor e Forma:White SolidPeso molecular:443.54SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Fórmula:C23H27FN4O4Pureza:98.13%Cor e Forma:Yellow SolidPeso molecular:442.48Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Fórmula:C26H27FN10Pureza:96.59% - 99.7%Cor e Forma:SolidPeso molecular:498.56Ref: TM-T5109
1mg35,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg222,00€50mg334,00€100mg557,00€200mg790,00€
