PDGFR
Os inibidores do receptor do fator de crescimento derivado de plaquetas (PDGFR) são compostos que bloqueiam a sinalização do PDGFR, um receptor envolvido no crescimento celular, proliferação e angiogênese. O PDGFR desempenha um papel significativo no desenvolvimento dos vasos sanguíneos que alimentam os tumores. Inibir o PDGFR pode, portanto, impedir a angiogênese, tornando esses inibidores valiosos na terapia contra o câncer. Na CymitQuimica, oferecemos uma seleção de inibidores de PDGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 126 produtos de "PDGFR"
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SU4312
CAS:<p>SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.</p>Fórmula:C17H16N2OPureza:>99.99%Cor e Forma:SolidPeso molecular:264.32PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Fórmula:C17H17N7Pureza:98.45% - 99.67%Cor e Forma:SolidPeso molecular:319.36Masitinib mesylate
CAS:<p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>Fórmula:C29H34N6O4S2Pureza:97.67% - 98.44%Cor e Forma:SolidPeso molecular:594.75TAK-593
CAS:<p>TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).</p>Fórmula:C23H23N7O3Pureza:99.37%Cor e Forma:SolidPeso molecular:445.47Seralutinib
CAS:<p>Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.</p>Fórmula:C27H27N5O3Pureza:99.09%Cor e Forma:SolidPeso molecular:469.54Amuvatinib
CAS:<p>Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.</p>Fórmula:C23H21N5O3SPureza:99.38% - >99.99%Cor e Forma:SolidPeso molecular:447.51PD-089828
CAS:<p>PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).</p>Fórmula:C18H18Cl2N6OPureza:97.39%Cor e Forma:SolidPeso molecular:405.28Crenolanib
CAS:<p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>Fórmula:C26H29N5O2Pureza:98.40% - 99.73%Cor e Forma:SolidPeso molecular:443.54Vorolanib
CAS:<p>Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.</p>Fórmula:C23H26FN5O3Pureza:97.35%Cor e Forma:SolidPeso molecular:439.48Masitinib
CAS:<p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>Fórmula:C28H30N6OSPureza:97.56% - >99.99%Cor e Forma:SolidPeso molecular:498.64Avapritinib
CAS:<p>Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.</p>Fórmula:C26H27FN10Pureza:96.59% - 99.7%Cor e Forma:SolidPeso molecular:498.56Nintedanib esylate
CAS:<p>Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β</p>Fórmula:C31H33N5O4·C2H6O3SPureza:99.43% - 99.96%Cor e Forma:SolidPeso molecular:649.76Multi-kinase inhibitor 1
CAS:<p>Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.</p>Fórmula:C20H17F3N4O3Pureza:99.34%Cor e Forma:SolidPeso molecular:418.37Ki20227
CAS:<p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Cor e Forma:SolidPeso molecular:480.54Toceranib Phosphate
CAS:<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Fórmula:C22H28FN4O6PPureza:98.56%Cor e Forma:SolidPeso molecular:494.45Flumatinib
CAS:<p>Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.</p>Fórmula:C29H29F3N8OPureza:99.39% - 99.95%Cor e Forma:SolidPeso molecular:562.59Tyrphostin A9
CAS:<p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>Fórmula:C18H22N2OPureza:98.21% - 99.87%Cor e Forma:Yellow SolidPeso molecular:282.38N-(p-Coumaroyl) serotonin
CAS:<p>N-(p-Coumaroyl) Serotonin, from safflower seeds, has antioxidant, antitumor properties and improves vascular health.</p>Fórmula:C19H18N2O3Pureza:98.10% - 98.89%Cor e Forma:SolidPeso molecular:322.36SU 5402
CAS:<p>SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.</p>Fórmula:C17H16N2O3Pureza:98.91% - 99.64%Cor e Forma:Yellow-Green SolidPeso molecular:296.32AZD2932
CAS:<p>AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.</p>Fórmula:C24H25N5O4Pureza:97.71% - 98.37%Cor e Forma:SolidPeso molecular:447.49
