Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1424 produtos de "Autofagia"
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KAN0438757
CAS:<p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>Fórmula:C21H18FNO7SPureza:99.34%Cor e Forma:SolidPeso molecular:447.43Pravastatin sodium
CAS:<p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>Fórmula:C23H35NaO7Pureza:97.14%Cor e Forma:White Crystalline PowderPeso molecular:446.52Raloxifene hydrochloride
CAS:<p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>Fórmula:C28H28ClNO4SPureza:98% - 99.97%Cor e Forma:Light Yellow SolidPeso molecular:510.044LY2183240
CAS:<p>LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM).</p>Fórmula:C17H17N5OPureza:99.26%Cor e Forma:SolidPeso molecular:307.35Ivermectin
CAS:<p>Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.</p>Fórmula:C48H74O14Pureza:94.11% - 99.71%Cor e Forma:SolidPeso molecular:875.09Clemastine fumarate
CAS:<p>Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.</p>Fórmula:C25H30ClNO5Pureza:99.52% - >99.99%Cor e Forma:Colorless To Faintly Yellow Crystalline Powder Appearance White Or Almost White Crystalline PowderPeso molecular:459.97Naringin
CAS:<p>Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.</p>Fórmula:C27H32O14Pureza:99.23%Cor e Forma:Beige Creamish Powder Solid Solid Particulate/PowderPeso molecular:580.53Sorafenib
CAS:<p>Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57</p>Fórmula:C21H16ClF3N4O3Pureza:98% - 99.89%Cor e Forma:SolidPeso molecular:464.82Aumitin
CAS:<p>Aumitin inhibits autophagy (IC50: 0.12-0.24μM), targets complex I, and blocks mitochondrial respiration.</p>Fórmula:C24H20ClN5OPureza:99.13%Cor e Forma:SolidPeso molecular:429.9Deferoxamine Mesylate
CAS:<p>Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.</p>Fórmula:C26H52N6O11SPureza:94.68% - 99.8%Cor e Forma:SolidPeso molecular:656.79Oxidopamine hydrochloride
CAS:<p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>Fórmula:C8H12ClNO3Pureza:98.34% - 99.85%Cor e Forma:Physical Description Beige Solid (Ntp 1992)Peso molecular:205.64Isoliquiritigenin
CAS:<p>Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.</p>Fórmula:C15H12O4Pureza:97.61% - 99.44%Cor e Forma:PowderPeso molecular:256.25Letrozole
CAS:<p>Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.</p>Fórmula:C17H11N5Pureza:98.67% - 99.84%Cor e Forma:White To Off-Whitecrystalline PowderPeso molecular:285.3Luteolin
CAS:<p>Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor.</p>Fórmula:C15H10O6Pureza:96.61% - 99.71%Cor e Forma:SolidPeso molecular:286.24Erlotinib
CAS:<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Fórmula:C22H23N3O4Pureza:98.19% - 99.98%Cor e Forma:White To Off-White PowderPeso molecular:393.44Theophylline
CAS:<p>Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central</p>Fórmula:C7H8N4O2Pureza:99.65% - 99.98%Cor e Forma:White Solid PowderPeso molecular:180.16Rhein
CAS:<p>Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.</p>Fórmula:C15H8O6Pureza:99.04%Cor e Forma:Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)Peso molecular:284.22Bergenin
CAS:<p>Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.</p>Fórmula:C14H16O9Pureza:99.55% - 99.60%Cor e Forma:The Loose White Needle Crystal Powder Or CrystallinePeso molecular:328.27Carvedilol phosphate hemihydrate
CAS:<p>Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.</p>Fórmula:C24H26N2O4·5H2O·H3O4PPureza:99.24% - 99.98%Cor e Forma:SolidPeso molecular:513.49Rosuvastatin calcium
CAS:<p>Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic</p>Fórmula:(C22H27FN3O6S)CaPureza:98.21% - 99.68%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:1001.14
