Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1431 produtos de "Autofagia"
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Urolithin A
CAS:<p>Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.</p>Fórmula:C13H8O4Pureza:99.14% - 99.67%Cor e Forma:SolidPeso molecular:228.2ZLN005
CAS:<p>ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.</p>Fórmula:C17H18N2Pureza:98.59% - >99.99%Cor e Forma:SolidPeso molecular:250.34TWS119
CAS:<p>TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation</p>Fórmula:C18H14N4O2Pureza:98.14% - 99.63%Cor e Forma:SolidPeso molecular:318.33Rutin hydrate
CAS:<p>Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.</p>Fórmula:C27H32O17Pureza:97.23%Cor e Forma:SolidPeso molecular:628.53Liensinine diperchlorate
CAS:<p>Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.</p>Fórmula:C37H44Cl2N2O14Pureza:99.8% - ≥95%Cor e Forma:SolidPeso molecular:811.67Entrectinib
CAS:<p>Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C31H34F2N6O2Pureza:98.03% - 99.61%Cor e Forma:SolidPeso molecular:560.64Quercetin
CAS:Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Fórmula:C15H10O7Pureza:96.29% - 98.05%Cor e Forma:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Peso molecular:302.24Bafilomycin A1
CAS:<p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>Fórmula:C35H58O9Pureza:95.87% - 99.36%Cor e Forma:SolidPeso molecular:622.83Dronedarone
CAS:<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Fórmula:C31H44N2O5SPureza:98.85% - 99.58%Cor e Forma:SolidPeso molecular:556.76PF-04457845
CAS:<p>PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).</p>Fórmula:C23H20F3N5O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:455.43MRT68921
CAS:<p>MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.</p>Fórmula:C25H34N6OPureza:99.23%Cor e Forma:SolidPeso molecular:434.58KU-55933
CAS:<p>KU-55933 (ATM Kinase Inhibitor) is an ATM inhibitor that is selective and ATP-competitive. KU-55933 has antitumor effects. Cost-effective and quality-assured.</p>Fórmula:C21H17NO3S2Pureza:97.21% - >99.99%Cor e Forma:SolidPeso molecular:395.49CGI-1746
CAS:<p>CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.</p>Fórmula:C34H37N5O4Pureza:97.69% - 97.88%Cor e Forma:SolidPeso molecular:579.69Tolvaptan
CAS:<p>Tolvaptan (OPC-41061) is an orally bioavailable, selective, arginine vasopressin receptor 2 (V2, AVPR2) antagonist that can be used to treat hyponatremia.</p>Fórmula:C26H25ClN2O3Pureza:99.78% - >99.99%Cor e Forma:SolidPeso molecular:448.94Telaglenastat hydrochloride
CAS:<p>Telaglenastat (CB-839) HCl: First-in-class, oral GLS1 inhibitor, targets KGA/GAC, IC50 23-28 nM, triggers autophagy, anticancer.</p>Fórmula:C26H25ClF3N7O3SCor e Forma:SolidPeso molecular:608.04Belinostat
CAS:Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.Fórmula:C15H14N2O4SPureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:318.35Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Fórmula:C21H26N6O2Pureza:96.01% - ≥98%Cor e Forma:SolidPeso molecular:394.47SBE13
CAS:<p>SBE13 is a selective and potent inhibitor of Plk1 (IC50: 200 pM). SBE13 has a weak effect on Plk2 or Plk3 with IC50 values of >66 μM and 875 nM respectively.</p>Fórmula:C24H27ClN2O4Cor e Forma:SolidPeso molecular:442.94Biochanin A
CAS:<p>Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.</p>Fórmula:C16H12O5Pureza:97.1% - 98.97%Cor e Forma:SolidPeso molecular:284.26Isodeoxyelephantopin
CAS:<p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>Fórmula:C19H20O6Pureza:99.88%Cor e Forma:SolidPeso molecular:344.36
