Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1492 produtos de "Autofagia"
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Nicardipine hydrochloride
CAS:Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.Fórmula:C26H30ClN3O6Pureza:99.58% - 99.89%Cor e Forma:Yellow SolidPeso molecular:515.99Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:99.41%Cor e Forma:Yellow SolidPeso molecular:925.46Sulfaguanidine
CAS:Sulfaguanidine (Guanicil), a sulfonamide, is served as an anti-infective agent.Fórmula:C7H10N4O2SPureza:97.78%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:214.24Quetmolimab
CAS:Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis.Pureza:SDS-PAGE:95% SEC-HPLC:97.59%Cor e Forma:LiquidPeso molecular:150 kDaNBDHEX
CAS:NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).Fórmula:C12H15N3O4SPureza:97.38%Cor e Forma:SolidPeso molecular:297.33Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Cor e Forma:Light Yellow Solid PowderPeso molecular:433.45Silmitasertib sodium salt
CAS:Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).Fórmula:C19H11ClN3NaO2Pureza:99.49% - 99.62%Cor e Forma:SolidPeso molecular:371.75Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Fórmula:C33H40N2O9Pureza:98.85% - 99.99%Cor e Forma:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Peso molecular:608.68BIX 02565
CAS:BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).Fórmula:C26H30N6O2Pureza:97.44% - 99.7%Cor e Forma:SolidPeso molecular:458.56Ref: TM-T5428
1mg56,00€2mg79,00€5mg118,00€10mg177,00€25mgA consultar50mgA consultar1mL*10mM (DMSO)145,00€Carboplatin
CAS:Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.
Fórmula:C6H12N2O4PtPureza:98% - 99.72%Cor e Forma:White Crystalline PowderPeso molecular:371.25Irinotecan Hydrochloride
CAS:Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.Fórmula:C33H39ClN4O6Pureza:98% - 99.94%Cor e Forma:Yellow Crystalline PowderPeso molecular:623.14Ref: TM-T0486L
10mg34,00€25mg49,00€50mg65,00€100mg89,00€200mg129,00€500mg254,00€1mL*10mM (DMSO)71,00€Acitretin
CAS:Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.Fórmula:C21H26O3Pureza:98.60% - 99.13%Cor e Forma:Crystals From Hexane SolidPeso molecular:326.43Dihydroartemisinin
CAS:Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!Fórmula:C15H24O5Pureza:98% - 99.41%Cor e Forma:White SolidPeso molecular:284.35EN6
CAS:EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.Fórmula:C19H14F2N4O2Pureza:95.74% - 97.04%Cor e Forma:SolidPeso molecular:368.34Ref: TM-T11191
1mg44,00€5mg84,00€10mg130,00€25mg195,00€50mg250,00€100mg379,00€500mg862,00€1mL*10mM (DMSO)66,00€Naringin
CAS:Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.Fórmula:C27H32O14Pureza:99.23%Cor e Forma:Beige Creamish Powder Solid Solid Particulate/PowderPeso molecular:580.53Fluoxetine
CAS:Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Fórmula:C17H18F3NOPureza:99.07% - 99.28%Cor e Forma:SolidPeso molecular:309.33Matrine
CAS:Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.Fórmula:C15H24N2OPureza:99.77% - >99.99%Cor e Forma:SolidPeso molecular:248.36Paclitaxel
CAS:Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.
Fórmula:C47H51NO14Pureza:98% - 99.92%Cor e Forma:White PowderPeso molecular:853.91Resveratrol
CAS:Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities.Fórmula:C14H12O3Pureza:99.82% - 99.96%Cor e Forma:Off-White To Tan PowderPeso molecular:228.24Ranolazine dihydrochloride
CAS:Ranolazine 2HCl, an antianginal, treats arrhythmia by inhibiting sodium current without changing blood pressure or heart rate.Fórmula:C24H35Cl2N3O4Pureza:99.30% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:500.46
